1
Tanamachi Dawn M, Brams Peter, Black Amelia: Transgenic animals expressing chimeric antibodies for use in preparing human antibodies. Medarex, Tanamachi Dawn M, Brams Peter, Black Amelia, GAVIN Kimberley A, October 18, 2007: WO/2007/117410 (50 worldwide citation)

The invention provides transgene constructs for expressing chimeric antibodies, and transgenic non-human host animals carrying such constructs, wherein the chimeric antibodies comprise human variable regions and constant regions of the non-human transgenic host animal. The presence of immunoglobulin ...


2
Dawn M Tanamachi, Peter Brams, Amelia Black: Transgenic animals expressing chimeric antibodies for use in preparing human antibodies. Medarex, Baker Botts L, March 22, 2011: US07910798 (37 worldwide citation)

The invention provides transgene constructs for expressing chimeric antibodies, and transgenic non-human host animals carrying such constructs, wherein the chimeric antibodies comprise human variable regions and constant regions of the non-human transgenic host animal. The presence of immunoglobulin ...


3
Dawn M Tanamachi, Peter Brams, Amelia Black: Transgenic animals expressing chimeric antibodies for use in preparing human antibodies. Medarex, Baker Botts, July 31, 2012: US08232449 (1 worldwide citation)

The invention provides transgene constructs for expressing chimeric antibodies, and transgenic non-human host animals carrying such constructs, wherein the chimeric antibodies comprise human variable regions and constant regions of the non-human transgenic host animal. The presence of immunoglobulin ...


4
Tanamachi Dawn M, Brams Peter, Black Amelia: Transgenic animals expressing chimeric antibodies for use in preparing human antibodies. Medarex, December 24, 2008: EP2003960-A2 (1 worldwide citation)

The invention provides transgene constructs for expressing chimeric antibodies, and transgenic non-human host animals carrying such constructs, wherein the chimeric antibodies comprise human variable regions and constant regions of the non-human transgenic host animal. The presence of immunoglobulin ...


5
Dawn M Tanamachi, Peter Brams, Amelia Black: Transgenic animals expressing chimeric antibodies for use in preparing human antibodies. E R SQUIBB & SONS L L C, Baker Botts L, December 29, 2015: US09220244

The invention provides transgene constructs for expressing chimeric antibodies, and transgenic non-human host animals carrying such constructs, wherein the chimeric antibodies comprise human variable regions and constant regions of the non-human transgenic host animal. The presence of immunoglobulin ...


6
TANAMACHI DAWN M, BRAMS PETER, BLACK AMELIA: Animaux transgéniques exprimant des anticorps chimériques pour une utilisation dans la préparation danticorps humains, Chimäre Antikörper exprimierende transgene Tiere für die Zubereitung humaner Antikörper, Transgenic animals expressing chimeric antibodies for use in preparing human antibodies. MEDAREX, October 3, 2012: EP2505058-A1

The invention provides transgene constructs for expressing chimeric antibodies, and transgenic non-human host animals carrying such constructs, wherein the chimeric antibodies comprise human variable regions and constant regions of the non-human transgenic host animal. The presence of immunoglobulin ...


7
Dawn M Tanamachi, Peter Brams, Amelia Black: Transgenic animals expressing chimeric antibodies for use in preparing human antibodies. Medarex, June 9, 2011: US20110138489-A1

The invention provides transgene constructs for expressing chimeric antibodies, and transgenic non-human host animals carrying such constructs, wherein the chimeric antibodies comprise human variable regions and constant regions of the non-human transgenic host animal. The presence of immunoglobulin ...


8
Dawn M Tanamachi, Peter Brams, Amelia Black: Transgenic animals expressing chimeric antibodies for use in preparing human antibodies. Baker Botts, October 15, 2009: US20090260093-A1

The invention provides transgene constructs for expressing chimeric antibodies, and transgenic non-human host animals carrying such constructs, wherein the chimeric antibodies comprise human variable regions and constant regions of the non-human transgenic host animal. The presence of immunoglobulin ...


9
Dawn M Tanamachi, Peter Brams, Amelia Black: Transgenic animals expressing chimeric antibodies for use in preparing human antibodies. October 25, 2012: US20120272344-A1

The invention provides transgene constructs for expressing chimeric antibodies, and transgenic non-human host animals carrying such constructs, wherein the chimeric antibodies comprise human variable regions and constant regions of the non-human transgenic host animal. The presence of immunoglobulin ...