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Nalin Subasinghe, Ehab Khalil, Kristi A Leonard, Farah Ali, Heather Hufnagel, Jeremy M Travins, Shelley K Ballentine, Kenneth T Wilson, Maxwell D Cummings, Wenxi Pan, Joan Gushue, Sanath Meegalla, Mark Wall, Jinsheng Chen, Jonathan M Rudolph, Hui Huang: Thiophene amidines, compositions thereof, and methods of treating complement-mediated diseases and conditions. 3 Dimensional Pharmaceuticals, November 21, 2006: US07138530 (11 worldwide citation)

Disclosed is a method for treating the symptoms of an acute or chronic disorder mediated by the classical pathway of the complement cascade, comprising administering to a mammal in need of such treatment a therapeutically effective amount of a compound of Formula (I) or a solvate, hydrate or pharmac ...


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Nalin Subasinghe, Ehab Khalil, Kristi Leonard, Farah Ali, Heather Rae Hufnagel, Jeremy M Travins, Shelley K Ballentine, Kenneth T Wilson, Maxwell D Cummings, Wenxi Pan, Joan Gushue, Sanath Meegalla, Mark Wall, Jinsheng Chen, M Jonathan Rudolph, Hui Huang: Thiophene amidines, compositions thereof, and methods of treating complement-mediated diseases and conditions. 3 Dimensional Pharmaceuticals, September 19, 2006: US07109354 (6 worldwide citation)

Disclosed is a method for treating the symptoms of an acute or chronic disorder mediated by the classical pathway of the complement cascade, comprising administering to a mammal in need of such treatment a therapeutically effective amount of a compound of Formula I or a solvate, hydrate or pharmaceu ...


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Subasinghe Nalin, Khalil Ehab, Leonard Kristi, Ali Farah, Hufnagel Heather Rae, Travins Jeremy M, Ballentine Shelley K, Wilson Kenneth T, Cummings Maxwell D, Pan Wenxi, Gushue Joan, Meegalla Sanath, Wall Mark, Chen Jinsheng, Rudolph M Jonathan, Huang Hui: Novel thiophene amidines, compositions thereof, and methods of treating complement-mediated diseases and conditions. Dimensional Pharm, July 6, 2005: EP1549632-A1

Disclosed is a method for treating the symptoms of an acute or chronic disorder mediated by the classical pathway of the complement cascade, comprising administering to a mammal in need of such treatment a therapeutically effective amount of a compound of Formula (I) or a solvate, hydrate or pharmac ...


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Nalin Subasinghe, Ehab Khalil, Kristi Leonard, Farah Ali, Heather Rae Hufnagel, Jeremy M Travins, Shelley K Ballentine, Kenneth T Wilson, Maxwell D Cummings, Wenxi Pan, Joan Gushue, Sanath Meegalla, Mark Wall, Jinsheng Chen, M Jonathan Rudolph, Hui Huang: Novel thiophene amidines, compositions thereof, and methods of treating complement-mediated diseases and conditions. 3 Dimensional Pharmaceuticals, Sterne Kessler Goldstein & Fox Pllc, January 15, 2004: US20040009995-A1

Disclosed is a method for treating the symptoms of an acute or chronic disorder mediated by the classical pathway of the complement cascade, comprising administering to a mammal in need of such treatment a therapeutically effective amount of a compound of Formula I 1 or a solvate, hydrate or pharmac ...


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Nalin Subasinghe, Ehab Khalil, Kristi A Leonard, Farah Ali, Heather Hufnagel, Jeremy M Travins, Shelley K Ballentine, Kenneth T Wilson, Maxwell D Cummings, Wenxi Pan, Joan Gushue, Sanath Meegalla, Mark Wall, Jinsheng Chen: Novel thiophene amidines, compositions thereof, and methods of treating complement-mediated diseases and conditions. Philip S Johnson, Johnson & Johnson, October 20, 2005: US20050234081-A1

Disclosed is a method for treating the symptoms of an acute or chronic disorder mediated by the classical pathway of the complement cascade, comprising administering to a mammal in need of such treatment a therapeutically effective amount of a compound of Formula (I) or a solvate, hydrate or pharmac ...


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Subasinghe Nalin, Khalil Ehab, Leonard Kristi: Novel thiophene amidines, compositions thereof, and methods of treating complement-mediated diseases and conditions. Dimensional Pharm, guo jianxin, September 7, 2005: CN03816116

Disclosed is a method for treating the symptoms of an acute or chronic disorder mediated by the classical pathway of the complement cascade, comprising administering to a mammal in need of such treatment a therapeutically effective amount of a compound of Formula (I) or a solvate, hydrate or pharmac ...


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Subasinghe Nalin, Khalil Ehab, Leonard Kristi, Ali Farah, Hufnagel Heather Rae, Travins Jeremy M, Ballentine Shelley K, Wilson Kenneth K, Cummings Maxwell D, Pan Wenxi, Gushue Joan, Meegalla Sanath, Wall Mark, Chen Jinsheng, Rudolph M Jonathan, Huang Hui: Novel thiophene amidines, compositions thereof, and methods of treating complement-mediated diseases and conditions. 3 Dimensional Pharmaceuticals, January 25, 2005: KR1020047019227

Disclosed is a method for treating the symptoms of an acute or chronic disorder mediated by the classical pathway of the complement cascade, comprising administering to a mammal in need of such treatment a therapeutically effective amount of a compound of Formula (I) or a solvate, hydrate or pharmac ...


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