1
Reinhard Sarges, Rodney C Schnur: Thienohydantoin derivatives. Pfizer, Francis X Murphy, Charles J Knuth, Peter C Richardson, November 28, 1978: US04127665 (17 worldwide citation)

Novel spiro-thienohydantoin derivatives useful as aldose reductase inhibitors and as therapeutic agents for the treatment of chronic diabetic complications are disclosed. Preferred compounds include 6,7-dihydro-spiro-[benzo(b)thiophene-4(5H),4'-imidazolidine]-2',5'-dione, 2-chloro-spiro-[cyclopenta( ...


2
Thienohydantoin derivatives. Pfizer, August 17, 1979: FR2415112-A1

Novel spiro-thienohydantoin derivatives useful as aldose reductase inhibitors and as therapeutic agents for the treatment of chronic diabetic complications are disclosed. Preferred compounds include 6,7-dihydro-spiro-[benzo(b)thiophene-4(5H),4'-imidazolidine]-2',5'-dione, 2-chloro-spiro-[cyclopenta( ...


3