1
Meguro Kanji, Fujita Takeshi: Thiazolidinedione derivatives, their production and use.. Takeda Chemical Industries, September 3, 1986: EP0193256-A1 (94 worldwide citation)

Thiazolidinedione derivatives of the formula: or pharmacologically acceptable salts thereof are novel compounds, which exhibit in mammals blood sugar- and lipid-lowering activity, and are of value as a therapeutic agent for diabetes and therapeutic agent for hyperlipemia.


2
Kanji Meguro, Takeshi Fujita: Thiazolidinedione derivatives, their production and use. Takeda Chemical, Wenderoth Lind & Ponack, February 16, 1988: US04725610 (79 worldwide citation)

Thiazolidinedione derivatives of the general formula: ##STR1## [wherein R.sup.1 is hydrogen or a hydrocarbon residue or heterocyclic residue which may each be substituted; R.sup.2 is hydrogen or lower alkyl which may be substituted by hydroxyl group; X is an oxygen or sulfur atom; Z is a hydroxylate ...


3
Meguro Kanji, Fujita Takeshi: Thiazolidinedione derivatives, their production and use.. Takeda Chemical Industries, April 9, 1986: EP0177353-A2 (59 worldwide citation)

Thiazolidinedione derivatives of the general formula: [wherein R is hydrogen or a hydrocarbon residue or heterocyclic residue which may each be substituted; R is hydrogen or lower alkyl which may be substituted by hydroxyl group; X is an oxygen or sulfur atom; Z is a hydroxylated methylene or carbon ...


4
Meguro Kanji, Fujita Takeshi: Thiazolidinedione derivatives, their production and use.. Takeda Chemical Industries, September 25, 1985: EP0155845-A1 (33 worldwide citation)

Thiazolidinedione derivatives of the general formula: [wherein R and R are the same or different and each represent hydrogen or a lower alkyl group; R is hydrogen or an acyl group; n is 0 or 1] and salts thereof are novel compounds, which exhibit in mammals blood sugar- and lipid-lowering activity, ...


5
Sohda Takashi, Ikeda Hitoshi, Imai Sachiko, Momose Yu: Thiazolidinedione derivatives, their production and use.. Takeda Chemical Industries, July 6, 1994: EP0605228-A1 (15 worldwide citation)

The object of the present invention is to provide a new thiazolidinedione derivative exhibiting excellent hypoglycemic and hypolipidemic action. Novel thiazolidinedione derivatives represented by the general formula (I): wherein n represents an integer of from 1 to 3; A represents an aromatic 5-memb ...


6
Takashi Sohda, Hiroyuki Odaka, Yu Momose: Thiazolidinedione derivatives, their production and use. Takeda Chemical, Wenderoth Lind & Ponack L, October 12, 1999: US05965589 (9 worldwide citation)

A 2,4-thiazolidinedione derivative of the formula (I): ##STR1## wherein R is an optionally substituted hydrocarbon group or heterocyclic group which may be attached through a hydrocarbon chain; n is 0 or 1; X is CH or N; Y is a bivalent hydrocarbon group; R.sup.1 and R.sup.2 are the same or differen ...


7
Takashi Sohda, Hitoshi Ikeda, Sachiko Imai, Yu Momose: Thiazolidinedione derivatives, their production and use. Takeda Chemical, Wenderoth Lind & Ponack, February 6, 1996: US05489602

The object of the present invention is to provide a new thiazolidinedione derivative exhibiting excellent hypoglycemic and hypolipidemic action.


8

9
Meguro Kanji, Fujita Takeshi: Derives de thiazolidinedione; preparation et utilisation, Thiazolidinedione derivatives, their production and use. Takeda Chemical Industries, FETHERSTONHAUGH & CO, December 5, 1989: CA1263655

A B S T R A C TThiazolidinedione derivatives of the general formula: Image [wherein R1 is hydrogen or a hydrocarbon residue or hetero-cyclic residue which may each be substituted; R2 is hydrogenor lower alkyl which may be substituted by hydroxyl group;X is an oxygen or sulfur atom; Z is a hydroxylat ...


10
Takashi Sohda, Hitoshi Ikeda, Sachiko Imai: Thiazolidinedione derivatives, their production and use. Takeda Chemical Industries, WANG JINGCHAO, November 9, 1994: CN93121754

The object of the present invention is to provide a new thiazolidinedione derivative exhibiting excellent hypoglycemic and hypolipidemic action. Thiazolidinedione derivative represented by the general formula, wherein n represents an integer from 1 to 3; A represents an aromatic 5membered heterocycl ...