1
Koszalka George Walter, Krenitsky Thomas Anthony: Therapeutic nucleosides and their preparation.. Wellcome Found, December 30, 1986: EP0206497-A2 (101 worldwide citation)

The present invention relates to certain 2 min ,3 min -dideoxynucleosides and pharmaceutically acceptable derivatives thereof, methods for preparing them, their use in the treatment and prophylaxis of viral, especially retroviral, infections, and pharmaceutical formulations containing them.


2
Rideout Janet Litster, Barry David Walter, Lehrman Sandra Nusinoff, St Clair Martha Heider, Furman Phillip Allen, Freeman George Andrew, Zimmerman Thomas Paul, Wolberg Gerald, de Miranda Paulo M, Shaver Sammy Ray, White Geoffrey, Kirk Iii Leone Edward, King Dannie Hilleary, Clemons Richard Harlon: Therapeutic nucleosides.. Wellcome Found, April 8, 1987: EP0217580-A2 (94 worldwide citation)

The present invention relates to certain novel 3 min -azidonucleosides and pharmaceutically acceptable derivatives thereof; the use of certain 3 min -azidonucleosides, their pharmaceutically acceptable derivatives and therapeutic combinations containing them, in therapy, particularly in the treatmen ...


3
Susan M Daluge: Therapeutic nucleosides. Burroughs Wellcome Co, Donald Brown, Lawrence A Nielsen, Hannah O Green, July 23, 1991: US05034394 (72 worldwide citation)

The present invention relates to 6-substituted purine carbocyclic nucleosides and their use in medical therapy particularly in the treatment of HIV and HBV infections. Also provided are pharmaceutical formulations and processes for the preparation of compounds according to the invention.


4
Daluge Susan Mary: Therapeutic nucleosides.. Wellcome Found, June 26, 1991: EP0434450-A2 (64 worldwide citation)

The present invention relates to 6-substituted purine carbocyclic nucleosides and their use in medical therapy particularly in the treatment of HIV and HBV infections. The invention also relates to pharmaceutical formulations and processes for the preparation of compounds according to the invention.


5
Daluge Susan Mary: Therapeutic nucleosides.. Wellcome Found, January 3, 1990: EP0349242-A2 (58 worldwide citation)

The present invention relates to 6-substituted purine carbocyclic nucleosides and their use in medical therapy particularly in the treatment and prophylaxis of HIV and HBV infections. Also provided are pharmaceutical formulations and processes for the preparation of compounds according to the invent ...


6
Rideout Janet Litster, Barry David Walter, Lehrman Sandra Nusinoff, St Clair Martha Heider, Furman Phillip Allen, Beacham Iii Lowrie Miller, Leblanc Harry Sidney, Freeman George Andrew: Therapeutic nucleosides.. Wellcome Found, October 29, 1986: EP0199451-A2 (38 worldwide citation)

3'-Azido-3'-deoxythymidine and its threo-3'-azido isomer and their pharmaceutically acceptable derivatives have been found to possess potent therapeutic activity, particularly against human and animal retroviral infections such as HTLV-I, HTLV-III and feline leukaemia virus, as well as against human ...


7
George W Koszalka, Charlene L Burns, Thomas A Krenitsky, Janet L Rideout: Therapeutic nucleosides. Burroughs Wellcome Co, Donald Brown, Lawrence A Nielsen, Hannah O Green, February 9, 1993: US05185437 (29 worldwide citation)

This invention relates to certain 6-substituted 2',3'-dideoxypurine nucleosides and pharmaceutically acceptable derivatives thereof and their use in the treatment of human immunodeficiency virus (HIV) and hepatitis B virus (HBV) infections. Also provided are pharmaceutical formulations and processes ...


8
Susan M Daluge: Therapeutic nucleosides. Burroughs Wellcome Co, Donald Brown, Lawrence A Nielsen, Hannah O Green, February 18, 1992: US05089500 (26 worldwide citation)

The present invention relates to 6-substituted purine carbocyclic nucleosides and their use in medical therapy particularly in the treatment of HIV and HBV infections. Also provided are pharmceutical formulations and processes for the preparation of compounds according to the invention.


9
George W Koszalka, Thomas A Krenitsky: Therapeutic nucleosides. Burroughs Wellcome Co, Donald Brown, Lawrence A Nielsen, Hannah O Green, December 10, 1991: US05071983 (24 worldwide citation)

This invention relates to certain derivatives of 2', 3'-dideoxycytidine and their use in medical therapy particularly in the treatment of HIV infections. Also provided are pharmaceutical formulations and processes for the manufacture of the compounds according to the invention.


10
Krenitsky Thomas Anthony, Beauchamp Lilia Marie: Therapeutic nucleosides.. Wellcome Found, March 22, 1989: EP0308065-A2 (20 worldwide citation)

The present invention relates to certain amino acid esters of the purine nucleoside acyclovir, pharmaceutically acceptable salts thereof and their use in the treatment and prophylaxis of herpes virus infections. The invention also includes pharmaceutical formulations and processes for the preparatio ...