1
Robert I Fox, Richard Houghton: Synthetic polypeptides and antibodies related to Epstein-Barr virus early antigen-diffuse. Scripps Clinic and Research Foundation, Dressler Goldsmith Shore Sutker & Milnamow, November 7, 1989: US04879213 (172 worldwide citation)

A synthetic polypeptide that contains about 6 to about 40 amino acid residues that immunologically mimics the early antigen-diffuse (EA-D) protein of the Epstein-Barr virus (EBV) is disclosed, as are receptors raised to that polypeptide, methods of their use and a reagent system. A polypeptide of th ...


2
Amnon Altman, Argyrios N Theofilopoulos, Richard A Lerner, Frank J Dixon: Antibodies to human interleukin-2 induced by synthetic polypeptides. Scripps Clinic and Research Foundation, Dressler Goldsmith Shore Sutker & Milnamow, January 13, 1987: US04636463 (32 worldwide citation)

Chemically synthesized polypeptides containing about 6 to about 40 amino acid residues having amino acid residue sequences that substantially correspond to the amino acid residue sequences of antigenic determinants of interleukin-2, when administered alone or as polymers or as conjugates bound to ca ...


3
George I Glover, Charles A McWherter, Charles S Schasteen: Serine protease inhibitors. Monsanto Company, Dennis R Hoerner Jr, Larry R Swaney, J W Williams Jr, May 9, 1989: US04829052 (29 worldwide citation)

Synthetic polypeptides are disclosed which exhibit potent serine protease inhibition. Methods and compositions useful for treating conditions caused by unwanted serine protease activity are also disclosed.


4
Amrit K Judd, Doris J Bucher, Steven W Popple: Synthetic peptides for diagnosis and prevention of influenza virus infection and their use. SRI International, Irell & Manella, January 1, 1991: US04981782 (28 worldwide citation)

Synthetic polypeptides having influenza virus antigenic properties are disclosed. These polypeptides correspond substantially to particular regions in the matrix protein of influenza virus. Salts, derivatives, and conjugates of these polypeptides are disclosed as well as methods for using these mate ...


5
Amrit K Judd, Doris J Bucher: Synthetic peptides for diagnosis and prevention of influenza virus infection and their use. SRI International, Richard P Lange, August 4, 1992: US05136019 (27 worldwide citation)

Synthetic polypeptides having influenza virus antigenic properties are disclosed. These polypeptides correspond substantially to the 215 to 235 region of the matrix protein of influenza virus. Salts, derivatives, and conjugates of these polypeptides are disclosed as well as methods for using these m ...


6
A Gururaj Rao, Lingxiu Zhong: Synthetic antimicrobial peptides. Pioneer Hi Bred International, Pioneer Hi Bred International, March 4, 1997: US05607914 (25 worldwide citation)

Synthetic polypeptides exhibiting amphipathic alpha-helices provide cell-expressible antimicrobial activity.


7
Friedman Paul A, Polokoff Mark A, Gould Robert J, Bencen Gerard H, Jacobs John W, Garsky Victor M, Gan Zhong Ru: Viper venom polypeptides and genetic expression.. Merck & Co, October 25, 1989: EP0338634-A2 (25 worldwide citation)

A platelet aggregation inhibiting polypeptide having the following amino acid sequence: X-Cys-R-R-R-Arg-Gly-Asp-R-R-R-R-R-Cys-Y where X is H or at least one amino acid; Y is OH or at least one amino acid; and each R, either the same or different, is any amino acid. Genetically engineered genes for t ...


8
Thomas M Shinnick, Percy Minden, Richard A Houghten: Synthetic polypeptides for detecting mycobacterial infections. Scripps Clinic and Research Foundation, Dressler Goldsmith Shore Sutker & Milnamow, August 25, 1987: US04689397 (25 worldwide citation)

Antigens, immunogens, inocula, antibodies, diagnostic methods and systems relating to tuberculous mycobacteria are disclosed. Each of the compounds, compositions, methods or systems contains a synthetic polypeptide having about 13 or 14 to about 40 residues, or an antibody containing site that immun ...


9
John H Vaughan, Dennis A Carson, Gary Rhodes, Richard Houghten, Richard S Smith, John E Geltosky: Assay for Epstein-Barr virus infection with solid phase bound synthetic polypeptides. Scripps Clinic and Research Foundation, Dressler Goldsmith Shore Sutker & Milnamow, May 26, 1992: US05116725 (20 worldwide citation)

Antigens, immunogens, inocula, antibodies, and particularly diagnostic methods and systems relating to Epstein-Barr virus nuclear antigen (EBNA) are disclosed. The diagnostic methods and systems utilize a synthetic, random copolymer polypeptide containing about 8 to about 40 amino acid residues that ...


10
Shibo Jiang, Kang Lin, A Robert Neurath: Synthetic polypeptides as inhibitors of HIV-1. New York Blood Center, Hoffmann & Baron, August 22, 1995: US05444044 (20 worldwide citation)

A synthetic HIV-1-based polypeptide as well as methods for topically inhibiting HIV-1 infectivity or replication. The polypeptide of the present invention has an amino acid sequence substantially corresponding to a specified region of the HIV-1.sub.IIIB virus. The polypeptide of the present inventio ...