1
Harold D Doshan, Julio Perez: Synthesis of R-N-methylnaltrexone. Progenics Pharmaceuticals, Wolf Greenfield & Sacks P C, March 9, 2010: US07674904 (25 worldwide citation)

This invention relates to stereoselective synthesis of R-MNTX and intermediates thereof, pharmaceutical preparations comprising R-MNTX or intermediates thereof and methods for their use.


2
Harold D Doshan, Julio Perez: Synthesis of (R)-N-methylnaltrexone. Progenics Pharmaceuticals, McCarter & English, Jonathan M Sparks Esq, Maneesh Gulati Esq, March 21, 2017: US09597327

This invention relates to stereoselective synthesis of R-MNTX and intermediates thereof, pharmaceutical preparations comprising R-MNTX or intermediates thereof and methods for their use.


3
Harold D Doshan, Julio Perez: Synthesis of R-N-methylnaltrexone. Wolf Greenfield & Sacks PC, May 3, 2007: US20070099946-A1

This invention relates to stereoselective synthesis of R-MNTX and intermediates thereof, pharmaceutical preparations comprising R-MNTX or intermediates thereof and methods for their use.


4
Harold D Doshan, Julio Perez: Synthesis of r-n-methylnaltrexone. Progenics Pharmaceuticals, Progenics Pharmaceuticals, c o WOLF GREENFIELD & SACKS PC, December 9, 2010: US20100311781-A1

This invention relates to stereoselective synthesis of R-MNTX and intermediates thereof, pharmaceutical preparations comprising R-MNTX or intermediates thereof and methods for their use.


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Doshan Harold D, Perez Julio: Synthesis of (R)-N-methylnaltrexone. Progenics Pharm, gu jinwei han hongxing, October 10, 2012: CN201210186704

This invention relates to stereoselective synthesis of R-MNTX and intermediates thereof, pharmaceutical preparations comprising R-MNTX or intermediates thereof and methods for their use.


8
SYNTHESIS OF R-N-METHYLNALTREXONE. PROGENICS PHARMACEUTICALS, December 5, 2013: US20130323286-A1

This invention relates to stereoselective synthesis of R-MNTX and intermediates thereof, pharmaceutical preparations comprising R-MNTX or intermediates thereof and methods for their use.


9
SYNTHESIS OF (R)-N-METHYLNALTREXONE. October 15, 2015: US20150290187-A1

This invention relates to stereoselective synthesis of R-MNTX and intermediates thereof, pharmaceutical preparations comprising R-MNTX or intermediates thereof and methods for their use.


10
SYNTHESIS OF (R)-N-METHYLNALTREXONE. PROGENICS PHARMACEUTICALS, February 26, 2015: US20150057303-A1

This invention relates to stereoselective synthesis of R-MNTX and intermediates thereof, pharmaceutical preparations comprising R-MNTX or intermediates thereof and methods for their use.