1
John N Staniforth, Bob E Sherwood, Edward A Hunter: Sustained-release formulations utilizing pharmaceutical excipient having improved compressibility. Edward Mendell Co, Steinberg Raskin & Davidson P C, April 21, 1998: US05741524 (103 worldwide citation)

Sustained release formulations include an augmented microcrystalline cellulose, an active agent, and a sustained release carrier and methods for making same are disclosed.


2
David Bodmer, Jones W Fong, Thomas Kissel, Hawkins V Maulding, Oskar Nagele, Jane E Pearson: Sustained release formulations of water soluble peptides. Sandoz, Robert S Honor, Carl W Battle, June 17, 1997: US05639480 (98 worldwide citation)

The invention discloses microparticles comprising a polypeptide, preferably somatostatin or an analog or derivative thereof, more preferably octreotide, in a polymeric matrix, preferably poly(lactide-co-glycolide)glucose. The invention also discloses sustained release formulations containing said mi ...


3
Fernand Labrie, Martin Lepage: Controlled release systems and low dose androgens. Endorecherche, Ostrolenk Faber Gerb & Soffen, July 18, 1995: US05434146 (94 worldwide citation)

Methods of treatment and prevention of estrogen-related diseases, and of fertility control, include low dose (e.g. less than 50 nanomolaR serum concentration) administration of certain anabolic steroids, progestins and other substantially non-masculinizing androgenic compounds. Sustained release for ...


4
Fernand Labrie, Martin Lepage: Controlled release systems and low dose androgens. Endorecherche, Ostrolenk Faber Gerb & Soffen, January 19, 1999: US05861387 (76 worldwide citation)

Methods of treatment and prevention of estrogen-related diseases, and of fertility control, include low dose (e.g. less than 50 nanomolar serum concentration) administration of certain anabolic steroids, progestins and other substantially non-masculinizing androgenic compounds. Sustained release for ...


5
Eugene L Walters: Sustained release diethylpropion compositions. Merrel Dow Pharmaceuticals, William J Stein, Gary D Street, Raymond A McDonald, December 20, 1983: US04421736 (72 worldwide citation)

Sustained release formulations for the anorectic agent, diethylpropion hydrochloride, are disclosed which are suitable for use in capsules.


6
John N Staniforth, Bob E Sherwood, Edward A Hunter: Sustained release formulations utilizing pharmaceutical excipient having improved compressibility with modified microcrystalline. Edward Mendell Co, Davidson Davidson & Kappel, January 12, 1999: US05858412 (65 worldwide citation)

Sustained release formulations include an augmented microcrystalline cellulose, an active agent, and a sustained release carrier and methods for making same are disclosed.


7
Brian W Barry, Bryan A Mulley, Peter York: Sustained-release formulations. APS Research, Spencer & Frank, October 8, 1991: US05055306 (61 worldwide citation)

A granular sustained-release formulation of a pharmacologically active substance presented in the form of a tablet, said tablet comprising sufficient granules to provide a predetermined dose or number of doses of the pharmacologically active substance and effervescent or water-dispersible ingredient ...


8
Reginald Phillips, Krishnayya Bikkina, Sadath U Khan: Sustained release formulations. Warner Lambert Company, Howard Olevsky, Ronald A Daignault, March 28, 1989: US04816264 (43 worldwide citation)

Drug delivery systems which exhibit sustained release properties when administered are produced using a "dual control" system which employs polymeric agents in core and membrane portions.


9
Franklin Okumu: Sustained release formulations. Genentech, Durect Corporation, Evan Law Group, January 31, 2006: US06992065 (42 worldwide citation)

A composition for sustained release comprises a carrier material containing a non-polymeric, non-water soluble liquid material having a viscosity of at least 5,000 cP at 37° C. that does not crytallize neat under ambient physiological conditions, a multivalent metal cation, and growth hormone.


10
David Bodmer, Jones W Fong, Thomas Kissel, Hawkins V Maulding Jr, Oskar Nagele, Jane E Pearson: Sustained release formulations of water soluble peptides. Sandoz, Robert S Honor, Carl W Battle, Joseph J Borovian, July 23, 1996: US05538739 (42 worldwide citation)

The invention discloses microparticles comprising a polypeptide, preferably somatostatin or an analog or derivative thereof, more preferably octreotide, in a polymeric matrix, preferably poly(lactide-co-glycolide) glucose. The invention also discloses sustained release formulations containing said m ...