1
Dosuk D Lee, Atul Nagras, Pramod Chakravarthy, Anthony M Majahad: Surface modification of medical implants. Etex Corporation, Mary Rose Scozzafava, Clark & Elbing, March 7, 2000: US06033582 (333 worldwide citation)

An irregularly etched medical implant device is provided having random non-uniform relief patterns on the surface ranging from about 0.3 .mu.m to less than about 20 .mu.m in depth. The random, irregular surface as defined by the etch micromorphology and respective dimensional properties are obtained ...


2
Youngro Byun, Yong Kyu Lee: Amphiphilic polysaccharide derivatives. Mediplex Corporation Korea, Clayton Howarth & Cannon P C, June 12, 2001: US06245753 (216 worldwide citation)

Polysaccharides, which are widely used as an anticoagulation drugs, especially heparin, are clinically administered only by intravenous or subcutaneous injection because of their strong hydrophilicity and high negative charge. Amphiphilic heparin derivatives were synthesized by conjugate to bile aci ...


3
Joseph A Chinn, Jack R Frautschi, Richard E Phillips: Prosthetic heart valve with surface modification. March 9, 2004: US06702851 (206 worldwide citation)

A biocompatible heart valve is described having incorporated therein an effective amount of applied coating to render the valve resistant to in vivo pathologic thrombus formation and resistant to in vivo pathologic calcification.


4
Alan S Rudolph, Chih Chang Chu, David A Stenger, Barry J Spargo, Jacque Georger: Surface modification of polymers with self-assembled monolayers that promote adhesion, outgrowth and differentiation of biological cells. United States of America represented by the Secretary of the Navy, Thomas McDonnell, John Karasek, February 24, 1998: US05721131 (184 worldwide citation)

A process for forming spatially oriented neo-vascular capillaries comprising: (a) providing a combination ultra-thin film (UTF) pattern of at least one cell adhesion promoter and at least one cell adhesion inhibitor wherein the cell adhesion promoters have a linewidth of between about 50-490 .mu.m; ...


5
Paul L Valint Jr, Joseph A McGee, Yu Chin Lai: Surface modification of polymer objects. Bausch & Lomb Incorporated, Craig E Larson, John E Thomas, June 15, 1993: US05219965 (177 worldwide citation)

A method of modifying the surfaces of polymeric objects by adding a polymerizable surfactant to the monomer mix used to form the object. Also disclosed are surface-modified objects prepared by this method, which is particularly suited for modifying the surfaces of contact lenses.


6
Joseph Andrew Chinn, Jack R Frautschi, Richard E Phillips Jr: Prosthetic heart valve with surface modification. Carbomedics, Williams Morgan & Amerson P C, July 20, 2004: US06764509 (159 worldwide citation)

Biocompatible prostheses, specifically, biocompatible heart valves, are described having incorporated therein an effective amount of coating applied thereto to render the valve resistant to in vivo pathologic thrombus formation and in vivo pathologic mineralization. Preferably, the coating is derive ...


7
D Morgan Tench, Leslie F Warren Jr, Michael A Cunningham: Reversible electrochemical mirror (REM) with improved electrolytic solution. Rockwell Science Center, Koppel & Jacobs, August 29, 2000: US06111685 (150 worldwide citation)

A reversible electrochemical mirror (REM) includes a first electrode and a second electrode, one of which is substantially transparent to at least a portion of the spectrum of electromagnetic radiation. An electrolytic solution, disposed between the first and second electrodes, contains ions of a me ...


8
Yeung Siu Yu, Mahesh Shah: Electrochemical test strip for use in analyte determination. LifeScan, Bret E Field, Carol M LaSalle, Bozicevic Field & Francis, April 6, 2004: US06716577 (150 worldwide citation)

Electrochemical test strips and methods for their use in the detection of an analyte in a physiological sample are provided. The subject test strips have a reaction zone defined by opposing metal electrodes separated by a thin spacer layer. The metal surface of at least one of the electrodes is modi ...


9
D Morgan Tench, Leslie F Warren Jr, Michael A Cunningham: Reversible electrochemical mirror for modulation of reflected radiation. Rockwell Technologies, James P O Shaughnessey, John J Deinken, December 26, 2000: US06166847 (141 worldwide citation)

An electrochemical mirror includes a transparent first electrode and a second electrode. An electrolytic solution, disposed between the first and second electrodes, contains ions of a metal which can electrodeposit on the electrodes. A negative electrical potential applied to the first electrode cau ...


10
Joshua Stopek, Brian Cuevas, Joseph Hotter, Brian Nentwick, Ali Irfan, Steven Tsai: Biomaterial drug delivery and surface modification compositions. Tyco Healthcare Group, December 14, 2010: US07850982 (140 worldwide citation)

Compositions are provided which include a polymer made at least in part from a polyoxyalkylene copolymer, such as a poloxamer. The polymer may be combined with a second component to form a blend or emulsion. The resulting composition may be utilized to form medical devices, drug delivery devices, or ...