1
Nathan B Mantlo, Stephen T Schlachter, John A Josey: Substituted pyridine compounds and methods of use. Amgen, Steve Odre, Ron Levy, Frank Ungemach, February 8, 2000: US06022884 (86 worldwide citation)

Selected novel substituted pyridine compounds are effective for prophylaxis and treatment of diseases, such as TNF-.alpha., IL-1.beta., IL-6 and/or IL-8 mediated diseases, and other maladies, such as pain and diabetes. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically ...


2
Nathan B Mantlo, Stephen T Schlachter, John A Josey: Substituted pyridine compounds and methods of use. Amgen, Frank S Ungemach, Stuart L Watt, December 25, 2001: US06333341 (22 worldwide citation)

Selected novel substituted pyridine compounds are effective for prophylaxis and treatment of diseases, such as TNF-&agr;, IL-1&bgr;, IL-6 and/or IL-8 mediated diseases, and other maladies, such as pain and diabetes. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically ac ...


3
Nathan B Mantlo, Stephen T Schlachter, John A Josey: Substituted pyridine compounds and methods of use. Amgen, Richard V Person, Frank S Ungemach, Steven M Odre, October 1, 2002: US06458813 (13 worldwide citation)

Selected novel substituted pyridine compounds are effective for prophylaxis and treatment of diseases, such as TNF-&agr;, IL-1&bgr;, IL-6 and/or IL-8 mediated diseases, and other maladies, such as pain and diabetes. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically ac ...


4
Nathan B Mantlo, Stephen T Schlachter, John A Josey: Substituted pyridine compounds and methods of use. Amgen, Frank Ungemach, Steven M Odre, February 6, 2001: US06184237 (2 worldwide citation)

Selected novel substituted pyridine compounds are effective for prophylaxis and treatment of diseases, such as TNF-&agr;, IL-1&bgr;, IL-6 and/or IL-8 mediated diseases, and other maladies, suchas pain and diabetes. The inventin encompasses novel compounds, analogs, prodrugs and pharmaceutically acce ...


5
Nathan B Mantlo, Stephen T Schlachter, John A Josey: Substituted pyridine compounds and methods of use. Amgen, Amgen Incorporated, March 21, 2002: US20020035094-A1

Selected novel substituted pyridine compounds are effective for prophylaxis and treatment of diseases, such as TNF-, IL-1, IL-6 and/or IL-8 mediated diseases, and other maladies, such as pain and diabetes. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically acceptable s ...