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Nomura Masahiro, Takahashi Yukie, Tanase Takahiro, Miyachi Hiroyuki, Tsunoda Masaki, Ide Tomohiro, Murakami Koji: Substituted phenylpropionic acid derivatives as agonists to human peroxisome proliferator-activated receptor alpha(ppar). Kyorin Seiyaku, March 6, 2002: EP1184366-A1 (16 worldwide citation)

The invention provides novel substituted phenylpropanoic acid derivatives that activate by binding to receptor as ligands of human peroxisome preliferant-activated receptor alpha (PPAR alpha ), and exhibit potent decreasing action on lipids in blood (cholesterol and triglyceride). It relates to subs ...


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Masahiro Nomura, Yukie Takahashi, Takahiro Tanase, Hiroyuki Miyachi, Masaki Tsunoda, Tomohiro Ide, Koji Murakami: Substituted phenylpropionic acid derivatives as agonists to human peroxisome proliferator-activated receptor (PPAR) &agr;. Kyorin Pharmaceutical, Oblon Spivak McClelland Maier & Neustadt P C, January 14, 2003: US06506797 (9 worldwide citation)

The invention provides novel substituted phenylpropanoic acid derivatives that activate by binding to receptor as ligands of human peroxisome preliferant-activated receptor &agr; (PPAR&agr;), and exhibit potent decreasing action on lipids in blood (cholesterol and triglyceride).


3
Nomura Masahiro, Takahashi Yukie, Tanase Takahiro, Miyachi Hiroyuki, Tsunoda Masaki, Ide Tomohiro, Murakami Koji: Derives dacide phenylpropionique substitues comme agonistes du recepteur humain active de la proliferation des peroxysomes (ppar) .alpha., Substituted phenylpropionic acid derivatives as agonists to human peroxisome proliferator-activated receptor (ppar) .alpha.. Kyorin Pharmaceutical, Kyorin Pharmaceutical, BORDEN LADNER GERVAIS, December 4, 2000: CA2376094 (2 worldwide citation)

The invention provides novel substituted phenylpropanoic acid derivatives that activate by binding to receptor as ligands of human peroxisome preliferant-activated receptor a (PPAR.alpha.), and exhibit potent decreasing action on lipids in blood (cholesterol and triglyceride). It relates to substitu ...


4
Eva Lotte Alstermark Lindstedt, Anna Christina Olsson, Lanna Li: Substituted phenylpropionic acid derivatives as agonists to human peroxisome proliferator-activated receptor α (PPAR). AstraZeneca, Fish & Richardson P C, April 7, 2009: US07514471

The present invention provides the S enantiomer of a compound of formula (I) wherein n is 1 or 2 as well as pharmaceutically acceptable salts, solvates, crystalline forms and prodrugs thereof, to processes for preparing such compounds, to their the utility in treating clinical conditions including l ...


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Alstermark Eva Lotte L, Olsson Anna C, Li Lanna: Substituted phenylpropionic acid derivatives as agonists to human peroxisome proliferator-activated receptor alpha (ppar). Astrazeneca, wang jingchao, January 17, 2007: CN200610007173

The present invention provides the S enantiomer of a compound of formula (I) wherein n is 1 or 2 as well as pharmaceutically acceptable salts, solvates, crystalline forms and prodrugs thereof, to processes for preparing such compounds, to their the utility in treating clinical conditions including l ...


8
Alstermark Lindstedt Eva Lotte, Olsson Anna Christina, Li Lanna: Substituted phenylpropionic acid derivatives as agonists to human peroxisome proliferator-activated receptor alpha(ppar). Astrazeneca, September 22, 2004: EP1458672-A1

The present invention provides the S enantiomer of a compound of formula (I); wherein R1 represents 2,4-difluorophenyl or cyclohexyl as well as pharmaceutically acceptable salts, solvates, crystalline forms and prodrugs thereof, to processes for preparing such compounds, to their the utility in trea ...


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Alstermark Lindstedt Eva Lotte, Olsson Anna Christina, Li Lanna: Substituted phenylpropionic acid derivatives as agonists to human peroxisome proliferator-activated receptor alpha (ppar). Astrazeneca, September 22, 2004: EP1458673-A1

The present invention provides the S enantiomer of a compound of formula (I); wherein R1 represents 2,4-difluorophenyl or cyclohexyl as well as pharmaceutically acceptable salts, solvates, crystalline forms and prodrugs thereof, to processes for preparing such compounds, to their the utility in trea ...


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Eva Lotte Alstermark Lindstedt, Anna Christina Olsson, Lanna Li: Substituted phenylpropionic acid derivatives as agonists to human peroxisome proliferator-activated receptor alpha (ppar). Fish & Richardson PC, August 4, 2005: US20050171204-A1

The present invention provides the S enantiomer of a compound of formula (I) wherein n is 1 or 2 as well as pharmaceutically acceptable salts, solvates, crystalline forms and prodrugs thereof, to processes for preparing such compounds, to their the utility in treating clinical conditions including l ...