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Deirdre Mary Bernadette Hickey, Dashyant Dhanak, Colin Andrew Leach, Robert John Ife, David Graham Tew: Substituted azetidin-2-ones for treatment of atherosclerosis. SmithKline Beecham, Wayne J Dustman, William T King, Charles M Kinzig, November 23, 1999: US05990102 (16 worldwide citation)

Compounds of formula (I) in which R.sup.1 and R.sup.2, which may be the same or different, is each selected from hydrogen, halogen or C.sub.(1-8) alkyl; R.sup.3 is aryl or aryl C.sub.(1-4) alkyl which may be optionally substituted; X is a linker group; Y is an optionally substituted aryl group; and ...


2
D M B Hickey, D Dhanak, C A Leach: Substituted azetidin-2-ones for treatment of atherosclerosis. Smithkline Beecham, LU XINHUA, March 4, 1998: CN95197606

Compounds of formula (I) in which R and R, which may be the same or different, is each selected from hydrogen, halogen or C(1-8)alkyl; R is aryl or arylC(1-4)alkyl which may be optionally substituted; X is a linker group; Y is an optionally substituted aryl group; and n is 0, 1 or 2; are inhibitors ...


3
Hickey Deirdre Mary Bernadette, Dhanak Dashyant, Leach Colin Andrew, Ife Robert John, Tew David Graham: Substituted azetidin-2-ones for treatment of atherosclerosis. Smithkline Beecham, Hickey Deirdre Mary Bernadette, Dhanak Dashyant, Leach Colin Andrew, Ife Robert John, Tew David Graham, sCONNELL Anthony Christopher, June 27, 1996: WO/1996/019451

Compounds of formula (I) in which R?1¿ and R?2¿, which may be the same or different, is each selected from hydrogen, halogen or C¿(1-8)?alkyl; R?3¿ is aryl or arylC¿(1-4)?alkyl which may be optionally substituted; X is a linker group; Y is an optionally substituted aryl group; and n is 0, 1 or 2; ar ...


4
Hickey Deirdre M B, Dhanak Dashyant, Leach Colin A, Ife Robert J, Tew David G: Substituted azetidin-2-ones for treatment of atherosclerosis. Smithkline Beecham, October 8, 1997: EP0799200-A1

Compounds of formula (I) in which R and R, which may be the same or different, is each selected from hydrogen, halogen or C(1-8)alkyl; R is aryl or arylC(1-4)alkyl which may be optionally substituted; X is a linker group; Y is an optionally substituted aryl group; and n is 0, 1 or 2; are inhibitors ...


5