1
Joseph J Nunes, Jill Milne, Jean Bemis, Roger Xie, Chi B Vu, Pui Yee Ng, Jeremy S Disch: Sirtuin modulating compounds. Sirtris Pharmaceuticals, Ropes & Gray, March 18, 2008: US07345178 (45 worldwide citation)

Provided herein are novel sirtuin-modulating compounds and methods of use thereof. The sirtuin-modulating compounds may be used for increasing the lifespan of a cell, and treating and/or preventing a wide variety of diseases and disorders including, for example, diseases or disorders related to agin ...


2
Jean Bemis, Jeremy S Disch, Michael Jirousek, Walter Joseph Lunsmann, Pui Yee Ng, Chi B Vu: Sirtuin modulating compounds. Sirtris Pharmaceuticals, Ropes & Gray, November 9, 2010: US07829556 (38 worldwide citation)

Provided herein are novel sirtuin-modulating compounds and methods of use thereof. The sirtuin-modulating compounds may be used for increasing the lifespan of a cell, and treating and/or preventing a wide variety of diseases and disorders including, for example, diseases or disorders related to agin ...


3
Nunes Joseph J, Milne Jill, Bemis Jean, Xie Roger, Vu Chi B, Ng Pui Yee, Disch Jeremy S: Imidazo [2,1-b] thiayole derivatives as sirtuin modulating compounds. Sirtris Pharmaceuticals, Nunes Joseph J, Milne Jill, Bemis Jean, Xie Roger, Vu Chi B, Ng Pui Yee, Disch Jeremy S, VINCENT Matthew P, February 15, 2007: WO/2007/019344 (29 worldwide citation)

Provided herein are novel sirtuin-modulating compounds and methods of use thereof. The sirtuin-modulating compounds may be used for increasing the lifespan of a cell, and treating and/or preventing a wide variety of diseases and disorders including, for example, diseases or disorders related to agin ...


4
Milburn Michael, Milne Jill, Bemis Jean, Nunes Joseph J, Xie Roger, Normington Karl D, Vu Chi B: Fused heterocyclic compounds and their use as sirtuin modulators. Sirtris Pharmaceuticals, Milburn Michael, Milne Jill, Bemis Jean, Nunes Joseph J, Xie Roger, Normington Karl D, Vu Chi B, VINCENT Matthew P, September 8, 2006: WO/2006/094235 (27 worldwide citation)

Provided herein are novel sirtuin-modulating compounds of formula (I) and methods of use thereof . The sirtuin-modulating compounds may be used for increasing the lifespan of a cell, and treating and/or preventing a wide variety of diseases and disorders including, for example, diseases or disorders ...


5
Milburn Michael, Milne Jill, Bemis Jean, Nunes Joseph J, Xie Roger, Normington Karl D, Vu Chi B: N-phenyl benzamide derivatives as sirtuin modulators. Sirtris Pharmaceuticals, Milburn Michael, Milne Jill, Bemis Jean, Nunes Joseph J, Xie Roger, Normington Karl D, Vu Chi B, VINCENT Matthew P, September 8, 2006: WO/2006/094236 (24 worldwide citation)

Provided herein are novel sirtuin-modulating compounds and methods of use thereof. The sirtuin-modulating compounds may be used for increasing the lifespan of a cell, and treatin and/or preventing a wide variety of diseases and disorders including, for example, diseases or disorders related to aging ...


6
Bemis Jean, Vu Chi B, Nunes Joseph J, Armistead David: (sir) Modulating compounds. Sirtris Pharmaceuticals, Bemis Jean, Vu Chi B, Nunes Joseph J, Armistead David, VINCENT Matthew P, June 19, 2008: WO/2008/073451 (23 worldwide citation)

A. Provided herein are novel sirtuin-modulating compounds of formula (I) and methods of use thereof. The sirtuin-modulating compounds may be used for increasing the lifespan of a cell, and treating and/or preventing a wide variety of diseases and disorders including, for example, diseases or disorde ...


7
Milburn Michael, Milne Jill, Normington Karl D, Nunes Joseph J, Salzmann Thomas, Sinclair David, Westphal Christoph H: Nicotinamide riboside and analogues thereof. Sirtris Pharmaceuticals, Milburn Michael, Milne Jill, Normington Karl D, Nunes Joseph J, Salzmann Thomas, Sinclair David, Westphal Christoph H, VINCENT Matthew P, October 5, 2006: WO/2006/105440 (22 worldwide citation)

Provided herein are sirtuin-modulating compounds and methods of use thereof. The sirtuin-modulating compounds may be used for increasing the lifespan of a cell, and treating and/or preventing a wide variety of diseases and disorders including, for example, diseases or disorders related to aging or s ...


8
Jean Bemis, Jeremy S Disch, Pui Yee Ng, Christopher Oalmann, Robert B Perni, Chi B Vu: Sirtuin modulating compounds. Sirtris Pharmaceuticals, Ropes & Gray, February 22, 2011: US07893086 (18 worldwide citation)

Provided herein are novel sirtuin-modulating compounds and methods of use thereof. The sirtuin-modulating compounds may be used for increasing the lifespan of a cell, and treating and/or preventing a wide variety of diseases and disorders including, for example, diseases or disorders related to agin ...


9
Joseph J Nunes, Jill Milne, Jean Bemis, Roger Xie, Chi B Vu, Pui Yee Ng, Jeremy S Disch, Thomas Salzmann, David Armistead: Sirtuin modulating compounds. Sirtris Pharmaceuticals, Ropes & Gray, December 21, 2010: US07855289 (18 worldwide citation)

Provided herein are novel sirtuin-modulating compounds and methods of use thereof. The sirtuin-modulating compounds may be used for increasing the lifespan of a cell, and treating and/or preventing a wide variety of diseases and disorders including, for example, diseases or disorders related to agin ...


10
Nunes Joseph J, Milne Jill, Bemis Jean, Xie Roger, Vu Chi B, Ng Pui Yee, Disch Jeremy S, Salzmann Thomas, Armistead David: Benzothiazoles and thiazolopyridines as sirtuin modulators. Sirtris Pharmaceuticals, Nunes Joseph J, Milne Jill, Bemis Jean, Xie Roger, Vu Chi B, Ng Pui Yee, Disch Jeremy S, Salzmann Thomas, Armistead David, VINCENT Matthew P, February 15, 2007: WO/2007/019346 (18 worldwide citation)

Provided herein are benzothiazol and thizolopyridine derivatires which are sirtuin-modulating compounds and methods of use thereof . The sirtuin-modulating compounds may be used for increasing the lifespan of a cell, and treating and/ or preventing a wide variety of diseases and disorders including, ...