1
COMBS Andrew P, LI Yun Long, YUE Eddy W: DÉRIVÉS DE PYRIMIDINE-4,6-DIAMINE EN TANT QUINHIBITEURS DE PI3K, PYRIMIDINE-4,6-DIAMINE DERIVATIVES AS PI3K INHIBITORS. INCYTE CORPORATION, COMBS Andrew P, LI Yun Long, YUE Eddy W, GOODSON Susanne H, October 4, 2012: WO/2012/135009 (22 worldwide citation)

The present invention provides pyrimidine-4,6-diamine derivatives of Formula (I): wherein the variables are defined herein, that modulate the activity of phosphoinositide 3-kinases (PI3Ks) and are useful in the treatment of diseases related to the activity of PI3Ks including, for example, inflammato ...


2
Andrew P Combs, Yun Long Li, Eddy W Yue, Song Mei: Pyrimidine-4,6-diamine derivatives as PI3K inhibitors. Incyte Holdings Corporation, Incyte Corporation, Fish & Richardson P C, September 8, 2015: US09126948 (1 worldwide citation)

The present invention provides pyrimidine-4,6-diamine derivatives of Formula (I): wherein the variables are defined herein, that modulate the activity of phosphoinositide 3-kinases (PI3Ks) and are useful in the treatment of diseases related to the activity of PI3Ks including, for example, inflammato ...


3
PYRIMIDINE-4,6-DIAMINE DERIVATIVES AS PI3K INHIBITORS. INCYTE CORPORATION, February 27, 2014: US20140057912-A1

The present invention provides pyrimidine-4,6-diamine derivatives of Formula (I): wherein the variables are defined herein, that modulate the activity of phosphoinositide 3-kinases (PI3Ks) and are useful in the treatment of diseases related to the activity of PI3Ks including, for example, inflammato ...