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Jagabandhu Das, Ramesh Padmanabha, Ping Chen, Derek J Norris, Arthur M P Doweyko, Joel C Barrish, John Wityak: Cyclic protein tyrosine kinase inhibitors. Bristol Myers Squibb Company, Ronald S Hermenau, July 22, 2003: US06596746 (91 worldwide citation)

Novel cyclic compounds and salts thereof, pharmaceutical compositions containing such compounds, and methods of using such compounds in the treatment of protein tyrosine kinase-associated disorders such as immunologic and oncologic disorders.


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Das Jagabandhu, Padmanabha Ramesh, Chen Ping, Norris Derek J, Doweyko Arthur M P, Barrish Joel, Wityak John, Lombardo Louis J, Lee Francis Y F: Cyclic protein tyrosine kinase inhibitors. Bristol Myers Squibb Company, Das Jagabandhu, Padmanabha Ramesh, Chen Ping, Norris Derek J, Doweyko Arthur M P, Barrish Joel, Wityak John, Lombardo Louis J, Lee Francis Y F, VANATTEN Mary K, October 7, 2004: WO/2004/085388 (88 worldwide citation)

Novel cyclic compounds and salts thereof, pharmaceutical compositions containing such compounds, and methods of using such compounds in the treatment of protein tyrosine kinase-associated disorders such as immunologic and oncologic disorders.


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George Stuart Cockerill, Malcolm Clive Carter, Stephen Barry Guntrip, Kathryn Jane Smith: Fused heterocyclic compounds as protein tyrosine kinase inhibitors. SmithKline Beecham Corporation, John L Lemanowicz, May 21, 2002: US06391874 (80 worldwide citation)

Substituted heteroaromatic compounds of formula (I) and in particular substituted quinolines and quinazolines, are protein tyrosine kinase inhibitors. The compounds are described as are methods for their preparation, pharmaceutical compositions including such compounds and their use in medicine, for ...


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George Stuart Cockerill, Malcolm Clive Carter, Stephen Barry Guntrip, Kathryn Jane Smith: Protein tyrosine kinase inhibitors. SmithKline Beecham Corporation, John L Lemanowicz, April 20, 2004: US06723726 (43 worldwide citation)

Substituted heteroaromatic compounds, and in particular substituted bicyclic heteroaromatic compounds of formula (I), wherein X is N or CH; A represents a fused 5, 6 or 7-membered heterocyclic ring containing 1 to 5 heteroatoms which may be the same or different and which are selected from N, O or S ...


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George Stuart Cockerill, Malcolm Clive Carter, Stephen Barry Guntrip, Kathryn Jane Smith: Heterocyclic compounds. SmithKline Beecham Corporation, John L Lemanowicz, December 7, 2004: US06828320 (40 worldwide citation)

Substituted heteroaromatic compounds, and in particular substituted quinolines and quinazolines, are protein tyrosine kinase inhibitors. The compounds are described as are methods for their preparation, pharmaceutical compositions including such compounds and their use in medicine, for example in th ...


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Ping Chen, Derek J Norris, Joel C Barrish, Edwin J Iwanowicz: Heterocyclo-substituted imidazopyrazine protein tyrosine kinase inhibitors. Bristol Myers Squibb Co, Audrey F Sher, November 23, 1999: US05990109 (38 worldwide citation)

Novel heterocyclo-substituted imidazopyrazines and salts thereof, pharmaceutical compositions containing such compounds, and methods of using such compounds in the treatment of protein tyrosine kinase-associated disorders such as immunologic disorders.


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George Stuart Cockerill, Malcolm Clive Carter, Stephen Barry Guntrip, Kathryn Jane Smith: Bicyclic heteroaromatic compounds as protein tyrosine kinase inhibitors. Glaxo Wellcome, John L Lemanowicz, January 16, 2001: US06174889 (38 worldwide citation)

Substituted heteroaromatic compounds, and in particular substituted bicyclic heteroaromatic compounds of formula (I), wherein X is N or CH; A represents a fused 5, 6 or 7-membered heterocyclic ring containing 1 to 5 heteroatoms which may be the same or different and which are selected from N, O or S ...


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George Stuart Cockerill, Malcolm Clive Carter, Stephen Barry Guntrip, Kathryn Jane Smith: Bicyclic heteroaromatic compounds as protein tyrosine kinase inhibitors. Glaxo Wellcome, John L Lemanowicz, March 27, 2001: US06207669 (33 worldwide citation)

Substituted heteroaromatic compounds, and in particular substituted bicyclic heteroaromatic compounds in which one ring is a pyridine or pyrimidine of formula (I) are protein tyrosine kinase inhibitors. The compounds are described as are methods for their preparation, pharmaceutical compositions inc ...