James A Williams: Vaccine for clostridium botulinum neurotoxin. Ophidian Pharmaceuticals, Medlen & Carroll, July 6, 1999: US05919665 (77 worldwide citation)

The present invention includes recombinant proteins derived from Clostridium botulinum toxins. In particular, soluble recombinant Clostridium botulinum type A toxin proteins are provided. Methods which allow for the isolation of recombinant proteins free of significant endotoxin contamination are pr ...

Pouletty Philippe, Pouletty Christine: Cellular drug anchors.. Pouletty Philippe, Pouletty Christine, June 22, 1994: EP0602290-A1 (37 worldwide citation)

Novel compositions are provided comprising a conjugate of a physiologically active compound and a receptor specific for a red cell, platelet or endothelial cell. The binding of the conjugate to the aforementioned cells provides for prolonged half-lives of the physiologically active compounds, provid ...

Mitchell R Swartz: Method for inactivating viruses, bacteria, etc. in vitro and production of vaccines. September 6, 1983: US04402318 (28 worldwide citation)

A method of inactivating viruses, bacteria, cells, toxins, etc., in vitro is disclosed. The disclosed method involves introducing an active agent capable of assuming an excited state when subjected to light, e.g., methylene blue, into the material to be inactivated. The virus, bacteria, etc. is then ...

Peter Meerts, Hans Nauwynck: Culturing circular ssDNA viruses for the production of vaccines. Universiteit Ghent, Clark & Elbing, November 27, 2007: US07300785 (25 worldwide citation)

The present invention relates to the use of interferon in the in vitro cultivation of animal circular ssDNA virus such as Porcine Circovirus 2 or human TT virus in an animal cell line. Increased titres of animal circular ssDNA virus are obtained by addition of interferons or agents which ensure the ...

Bachmann Martin F, Tissot Alain, Ortmann Rainer, Lüönd Rainer, Staufenbiel Matthias, Frey Peter: Vaccine compositions containing amyloid beta1-6 antigen arrays. Cytos Biotechnology, Novartis Pharma, Bachmann Martin F, Tissot Alain, Ortmann Rainer, Lüönd Rainer, Staufenbiel Matthias, Frey Peter, WICHMANN Hendrik, February 26, 2004: WO/2004/016282 (24 worldwide citation)

The present invention is related to the fields of molecular biology, virology, immunology and medicine. The invention provides a composition comprising an ordered and repetitive antigen or antigenic determinant array, and in particular an A&bgr;1-6 peptide-VLP-composition. More specifically, the inv ...

Harry B Greenberg, Richard G Wyatt, Albert Z Kapikian, Anthony R Kalica, Karen Midthun, Robert M Chanock: Genetic reassortment of rotaviruses for production of vaccines and vaccine precursors. The United States of America represented by the Department of Health and Human Services, John S Roberts Jr, February 18, 1986: US04571385 (23 worldwide citation)

This invention relates to processes which are used to produce, isolate, and characterize human rotavirus/animal rotavirus reassortants and to produce live attenuated vaccines and vaccine precursors. In the present strategy there is involved the new use of either (1) high titer hyperimmune antisera o ...

John Sidney Oxford: Vaccines and methods for their production. Retroscreen, Rick Martin, December 16, 1997: US05698432 (22 worldwide citation)

The present invention relates to the production of vaccines having improved safety, particularly to a process therefor which allows even an AIDS vaccine to be manufactured, comprising in order, the steps of:

Arielle Rey Senelonge, Gilla Kohen: Recombinant herpesviruses, in particular for the production of vaccines, process for preparing them, plasmids produced during this process and vaccines obtained. Rhone Merieux, Larson and Taylor, November 30, 1993: US05266489 (18 worldwide citation)

The recombinant virus chosen from the turkey herpesvirus(HVT), Aujeszky's disease virus (PRV), infectious bovine rhinotracheitis virus (BHV) feline infectious rhinotracheitis virus (FHV), equine rhinopneumonia virus (EHV), canine herpesvirus (CHV), duck herpesvirus, human simplex herpesvirus (HSV), ...

Dale Emil Bordt, Phillip Clay Thomas: Diploid porcine embryonic cell strains, cultures produced therefrom, and use of said cultures for production of vaccines. Syntex, Gerard A Blaufarb, January 24, 1978: US04070453 (17 worldwide citation)

Diploid porcine embryonic cell strains, method of growing same from porcine embryonic tissue, culturing and subculturing said diploid cell strains, and preparing a virus vaccine (exemplary of the virus vaccine thus prepared is a porcine transmissible gastroenteritis virus vaccine) from said diploid ...

Igor Stojiljkovic, Magdalene So, Vivian Hwa, Fred Heffron, Xavier Nassif: Bacterial hemoglobin receptor genes. Oregon Health and Science University, McDonnell Boehnen Hulbert & Berghoff, April 11, 2006: US07026157 (16 worldwide citation)

The present invention relates to novel bacterial hemoglobin receptor proteins and genes that encode such proteins. The invention is directed toward the isolation, characterization, diagnostic and therapeutic use of bacterial hemoglobin receptor proteins, nucleic acid encoding such proteins, recombin ...

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