1
Edith Mathiowitz, Yong Shik Jong, Kim Boekelheide: Polymeric gene delivery system. Neurotech, Ivor R Elrifi Esquire, Mintz Levin Cohn Ferris Glovsky and Popeo P C, July 17, 2001: US06262034 (207 worldwide citation)

A means for obtaining efficient introduction of exogenous genes into a patient, with long term expression of the gene, is disclosed. The gene, under control of an appropriate promoter for expression in a particular cell type, is encapsulated or dispersed with a biocompatible, preferably biodegradabl ...


2
Edith Mathiowitz, Yong Shik Jong, Kim Boekelheide: Polymeric gene delivery system. Brown University Research Foundation, Ivor R Elrifi Esq, Christina V Karnakis Esq, Mintz Levin Cohn Ferris Glovsky and Popeo P C, September 16, 2003: US06620617 (86 worldwide citation)

A means for obtaining efficient introduction of exogenous genes into a patient, with long term expression of the gene, is disclosed. The gene, under control of an appropriate promoter for expression in a particular cell type, is encapsulated or dispersed with a biocompatible, preferably biodegradabl ...


3
Mathiowitz Edith, Jong Yong Shik, Boekelheide Kim: Polymeric gene delivery system. Brown University Research Foundation, ELFIRI Ivor R, September 21, 1995: WO/1995/024929 (1 worldwide citation)

A means for obtaining efficient introduction of exogenous genes into a patient, with long term expression of the gene, is disclosed. The gene, under control of an appropriate promoter for expression in a particular cell type, is encapsulated or dispersed with a biocompatible, preferably biodegradabl ...


4
Richard T Lee: 1L1RL-1 as a cardiovascular disease marker and therapeutic target. The Brigham & Women s Hosptial, Fish & Richardson P C, December 26, 2017: US09851362

This invention pertains to methods and compositions for the diagnosis and treatment of cardiovascular conditions. More specifically, the invention relates to isolated molecules that can be used to diagnose and/or treat cardiovascular conditions including cardiac hypertrophy, myocardial infarction, s ...


5
Richard T Lee: Methods for treatment of cardiovascular disease. The Brigham and Women s Hospital, Fish & Richardson P C, January 2, 2018: US09857379

This invention pertains to methods and compositions for the diagnosis and treatment of cardiovascular conditions. More specifically, the invention relates to isolated molecules that can be used to diagnose and/or treat cardiovascular conditions including cardiac hypertrophy, myocardial infarction, s ...


6
Victor May, Kerry J Ressler, Sayamwong E Hammack, Donna Toufexis, Karen M Braas: Diagnostic and therapeutic methods and products related to anxiety disorders. The University of Vermont and State Agricultural College, Wolf Greenfield & Sacks P C, April 10, 2018: US09939449

The present disclosure provides methods for diagnosing and treating anxiety disorders in female subjects. Diagnosis and treatment of such anxiety disorders are based, in part, on an analysis of pituitary adenylate cyclase-activating polypeptide (PACAP) expression levels in tissue collected from fema ...


7
Yoav D Shaul, David M Sabatini: Metabolic gene mesenchymal signatures and uses thereof. Whitehead Institute for Biomedical Research, Wolf Greenfield & Sacks P C, January 24, 2017: US09551036

Aspects of the invention relate to methods and compositions for characterizing or modulating the expression of metabolic mesenchymal genes. In some embodiments, methods for assessing the expression of metabolic mesenchymal genes and related gene signatures are provided that are useful for cancer cla ...


8
Edith Mathiowitz, Yong Shik Jong, Kim Boekelheide: Polymeric gene delivery system. c o MINTZ LEVIN, September 6, 2001: US20010020011-A1

A means for obtaining efficient introduction of exogenous genes into a patient, with long term expression of the gene, is disclosed. The gene, under control of an appropriate promoter for expression in a particular cell type, is encapsulated or dispersed with a biocompatible, preferably biodegradabl ...


9
Edith Mathiowitz, Yong Shik Jong, Kim Boekelheide: Polymeric gene delivery system. Mintz Levin Cohn Ferris Glovsky, And Popeo PC, July 1, 2004: US20040126884-A1

A means for obtaining efficient introduction of exogenous genes into a patient, with long term expression of the gene, is disclosed. The gene, under control of an appropriate promoter for expression in a particular cell type, is encapsulated or dispersed with a biocompatible, preferably biodegradabl ...


10
Mathiowitz Edith, Jong Yong Shik, Boekelheide Kim: Polymeric gene delivery system. Univ Brown Res Found, November 5, 1997: EP0804249-A2

A means for obtaining efficient introduction of exogenous genes into a patient, with long term expression of the gene, is disclosed. The gene, under control of an appropriate promoter for expression in a particular cell type, is encapsulated or dispersed with a biocompatible, preferably biodegradabl ...