1
John Hakimi, Patricia Kilian, Perry Rosen: Polyethylene-protein conjugates. Hoffmann La Roche, George W Johnston, William H Epstein, Lewis J Kreisler, May 5, 1998: US05747646 (127 worldwide citation)

The present invention is a physiologically active, substantially non-immunogenic water soluble polyethylene glycol protein conjugate having the same utility as the protein which forms the conjugate, without having the same properties of producing an immunogenic response possessed by the protein whic ...


2
John Hakimi, Patricia Kilian, Perry Rosen: Polyethylene-protein conjugates. Hoffman La Roche, George W Johnston, William H Epstein, Lewis J Kreisler, November 10, 1998: US05834594 (120 worldwide citation)

The present invention is a physiologically active, substantially non-immunogenic water soluble polyethylene glycol protein conjugate having the same utility as the protein which forms the conjugate, without having the same properties of producing an immunogenic response possessed by the protein whic ...


3
John Hakimi, Patricia Kilian, Perry Rosen: Polyethylene-protein conjugates. Hoffmann La Roche, George W Johnston, William H Epstein, Briana C Buchholz, December 15, 1998: US05849860 (99 worldwide citation)

The present invention is a physiologically active, substantially non-immunogenic water soluble polyethylene glycol protein conjugate having the same utility as the protein which forms the conjugate, without having the same properties of producing an immunogenic response possessed by the protein whic ...


4
John Hakimi, Patricia Kilian, Perry Rosen: Polyethylene-protein conjugates. Hoffmann La Roche, George W Johnston, William H Epstein, Catherine R Smith, September 24, 1996: US05559213 (84 worldwide citation)

The present invention is a physiologically active, substantially non-immunogenic water soluble polyethylene glycol protein conjugate having the same utility as the protein which forms the conjugate, without having the same properties of producing an immunogenic response possessed by the protein whic ...


5
John Hakimi, Patricia Kilian, Perry Rosen: Polyethylene-protein conjugates. Hoffmann La Roche, George W Johnston, William H Epstein, Lewis J Kreisler, August 11, 1998: US05792834 (69 worldwide citation)

The present invention is a physiologically active, substantially non-immunogenic water soluble polyethylene glycol protein conjugate having the same utility as the protein which forms the conjugate, without having the same properties of producing an immunogenic response possessed by the protein whic ...


6
John Hakini, Patricia Kilian, Perry Rosen: Polyethylene-protein conjugates. Hoffmann La Roche, George W Johnston, William H Epstein, Catherine R Smith, January 21, 1997: US05595732 (23 worldwide citation)

The present invention is a physiologically active, substantially non-immunogenic water soluble polyethylene glycol protein conjugate having the same utility as the protein which forms the conjugate, without having the same properties of producing an immunogenic response possessed by the protein whic ...


7
Hakimi John, Kilian Patricia, Rosen Perry: Proteines conjuguees au polyethylene, Polyethylene protein conjugates. F Hoffmann La Roche, F Hoffmann La Roche, GOWLING LAFLEUR HENDERSON, August 20, 2002: CA2063886

The present invention relates to physiologically active,substantially non-immunogenic water soluble polyethylene glycolprotein conjugates having at least part of the biological activity of theprotein which forms the conjugate, without exhibiting the samedisadvantageous immunogenic responses thereof.


8
John Hakimi, Patricia Kilian, Perry Rosen: Polyethylene protein conjugates. Fhoffmann La Roche &Amp Co, WANG JINGCHAO WANG YANG, October 21, 1992: CN92101994

The present invention is a physiologically active, substantially non-immunogenic water soluble polyethylene glycol protein conjugate having the same utility as the protein which forms the conjugate, without having the same properties of producing an immunogenic response possessed by the protein whic ...