1
Ernst P Krebs: Polyene compounds. Hoffmann La Roche, Jon S Saxe, Bernard S Leon, William H Epstein, September 3, 1985: US04539154 (46 worldwide citation)

9-(cyclohexenyl or phenyl)-4,7-dimethyl-2,4,6,8-nonatetraenoic acid derivatives as well as 7-(5,6,7,8-tetrahydro-5,5,8,8,-tetramethyl-2-naphthyl)-4-methyl-2,4,6-octa trienoic acid derivatives useful for the treatment of neoplasms, premalignant lesions, acne, psoriasis and rheumatic diseases of an in ...


2
Peter Loeliger: Polyene compounds. Hoffmann La Roche, Jon S Saxe, Bernard S Leon, George W Johnston, March 18, 1980: US04193931 (41 worldwide citation)

Novel 7-(substituted indanyl or naphthyl)-3-methyl-octa-2,4,6-triene derivatives useful as anti-tumor agents are disclosed.


3
Dmitri Ptchelintsev: Composition and method for treating rosacea and sensitive skin with free radical scavengers. Avon Products, Ohlandt Greeley Ruggiero & Perle, October 26, 1999: US05972993 (35 worldwide citation)

A method for treating skin conditions, such as rosacea and sensitive skin, that manifest as a tendency towards flushing and blushing is provided. Also provided herein, are compositions for the treatment of rosacea and sensitive skin that are comprised of at least one antioxidant selected from the fo ...


4
Beverly Ann Pawson: Polyene compounds. Hoffmann La Roche, Samuel L Welt, Jon S Saxe, R Hain Swope, January 6, 1976: US03931257 (25 worldwide citation)

Novel 9-substituted phenyl- or cyclohex-1-en-1-yl-3,7-dimethyl-nona-2,4,6-trienoic acids or derivatives thereof, -trienal or -trienol derivatives are described. The subject compounds are useful in the treatment of certain dermatoses and inflammatory and allergic dermatological conditions.


5
Pawson Beverley Ann: Polyene compounds, their preparation and pharmaceutical preparations containing them.. Hoffmann La Roche, June 20, 1984: EP0111124-A1 (25 worldwide citation)

Verbindungen der allgemeinen Formel worin R nieder-Alkyl oder Halogen, R nieder-Alkyl, R nieder-Alkyl oder Halogen, R -CH2-OH, R Wasserstoff, Hydroxy oder nieder- Alkoxy und R und R Wasserstoff oder nieder-Alkyl bedeuten, und Salze von Carbonsäuren der Formel I. Die Verbindung der Formel I und deren ...


6
Werner Bollag, Rudolf Ruegg, Gottlieb Ryser: Polyene compounds. Hoffmann La Roche, Samuel L Welt, Bernard S Leon, R Haine Swope, October 5, 1976: US03984440 (24 worldwide citation)

Novel 9-substituted phenyl-3,7-dimethyl-nona-2,4,6,8-tetraenoic acid, -tetraenal or -tetraenol derivatives are described. The subject compounds are useful in the treatment of neoplasias, certain dermatoses and inflammatory and allergic dermatological conditions.


7
Michael Josef Klaus, Beverly Ann Pawson: Polyene compounds. Hoffmann La Roche, Samuel L Welt, Bernard S Leon, William H Epstein, December 6, 1977: US04061656 (20 worldwide citation)

Novel 9-substituted or unsubstituted thienyl-3,7-dimethyl-nona-2,4,6,8-tetraene derivatives, useful as antitumor agents as well as processes for their preparation and novel intermediates are disclosed.


8
Kazuo Ohkawa, Seiichi Saito: Optical molding resin composition comprising polythiol-polyene compounds. Asahi Denka Kogyo, Flynn Thiel Boutell & Tanis, August 17, 1993: US05236967 (19 worldwide citation)

An optical molding composition is used for casting and does not cause irritation to the skin or possess a bad smell. This composition comprises


9
Bernard Loev, Wan Kit Chan, Howard Jones: Polyene compounds useful in the treatment of psoriasis and allergic responses. USV Pharmaceutical, August 13, 1985: US04534979 (17 worldwide citation)

Polyene compounds represented by the general formulae ##STR1## in which: R and R.sub.1 are each hydrogen or an alkyl group of from 1 to 5 carbon atoms;


10
Frank Kienzle: Polyene compounds. Hoffmann La Roche, Jon S Saxe, Bernard S Leon, William H Epstein, May 22, 1979: US04156090 (15 worldwide citation)

15,15'-Didehydro-astaxanthin and ester derivatives thereof useful as coloring agents and intermediates for astaxanthin and a method for preparing astaxanthin from keto .alpha.-isophorone and intermediates therein.