1
Kettner Charles Adrian, Shenvi Ashokkumar Bhikkappa: Peptide boronic acid inhibitors of trypsin-like proteases.. Du Pont, December 7, 1988: EP0293881-A2 (124 worldwide citation)

Peptides comprising C-terminal boronic acid derivatives of lysine, ornithine, and arginine, homoarginine and corresponding isothiouronium analogs thereof, of the formula are reversible inhibitors of trypsin-like serine proteases such as thrombin, plasma kallikrein and plasmin.


2
Charles A Kettner, Ashokkumar B Shenvi: Peptide boronic acid inhibitors of trypsin-like proteases. Du Pont Merck Pharmaceutical Company, Blair Q Ferguson, Suzanne E Miller, February 16, 1993: US05187157 (82 worldwide citation)

Peptides comprising C-terminal boronic acid derivatives of lysine, ornithine, and arginine, homoarginine and corresponding isothiouronium analogs thereof, are reversible inhibitors of trypsin-like serine proteases such as thrombin, plasma kallikrein and plasmin.


3
Charles A Kettner, Ashokkumar B Shenvi: Peptide boronic acid inhibitors of trypsin-like proteases. The Dupont Merck Pharmaceutical Company, Blair Q Ferguson, Suzanne Miller, September 7, 1993: US05242904 (44 worldwide citation)

Peptides comprising C-terminal boronic acid derivatives of lysine, ornithine, and arginine, homoarginine and corresponding isothiouronium analogs thereof, are reversible inhibitors of trypsin-like serine proteases such as thrombin, plasma kallikrein and plasmin.


4
Charles A Kettner, Ashokkumar B Shenvi: Intermediates for preparing peptide boronic acid inhibitors of trypsin-like proteases. The Dupont Merck Pharmaceutical Company, Blair Q Ferguson, Suzanne Miller, October 5, 1993: US05250720 (41 worldwide citation)

Intermediates for the preparation of Peptides comprising C-terminal boronic acid derivatives of lysine, ornithine, and arginine, homoarginine and corresponding isothiouronium analogs thereof, are reversible inhibitors of trypsin-like serine proteases such as thrombin, plasma kallikrein and plasmin.


5
Kettner Charles Adrian, Shenvi Ashokkumar Bhikkappa: Inhibiteurs de type derives acide boronique de peptides pour des proteases semblables a la trypsine, Peptide boronic acid inhibitors of trypsin-like proteases. Kettner Charles Adrian, Shenvi Ashokkumar Bhikkappa, The Du Pont Merck Pharmaceutical Company, SIM & MCBURNEY, April 5, 1994: CA1328332

TITLEPeptide Boronic AcidInhibitors of Trypsin-Like Proteases ABSTRACTPeptides comprising C-terminal boronic acidderivatives of lysine, ornithine, and arginine,homoarginine and corresponding isothiouronium analogsthereof, are reversible inhibitors of trypsin-likeserine proteases such as thrombin, pl ...


6
Kettner Charles Adrian, Shenvi Ashokkumar Bhikkappa: Peptides contenant de lacide boronique inhibant les proteases apparentees a la trypsine, Peptide boronic acid inhibitors of trypsin-like proteases. Kettner Charles Adrian, Shenvi Ashokkumar Bhikkappa, The Du Pont Merck Pharmaceutical Company, SIM & MCBURNEY, November 22, 1994: CA1333208

Peptides comprising C-terminal boronic acidderivatives of lysine, ornithine, and arginine,homoarginine and corresponding isothiouronium analogsthereof, are reversible inhibitors of trypsin-likeserine proteases such as thrombin, plasma kallikreinand plasmin.


7
Shenvi Ashokkumar Bhikkappa, Kettner Charles Adrian: Inhibiteurs a base dacide boronique peptidique pour proteases de type trypsine, Peptide boronic acid inhibitors of trypsin-like proteases. Shenvi Ashokkumar Bhikkappa, Kettner Charles Adrian, The Du Pont Merck Pharmaceutical Company, SIM & MCBURNEY, June 2, 1998: CA1339897

Peptides comprising C-terminal boronic acidderivatives of lysine, ornithine, and arginine,homoarginine and corresponding isothiouronium analogsthereof, are reversible inhibitors of trypsin-likeserine proteases such as thrombin, plasma kallikreinand plasmin.