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Benjamin Hindson, Serge Saxonov, Kevin Ness, Paul Hardenbol, Michael Schnall Levin, Mirna Jarosz: Methods and systems for processing polynucleotides. 10X GENOMICS, Wilson Sonsini Goodrich & Rosati, January 2, 2018: US09856530 (4 worldwide citation)

The present disclosure provides compositions, methods, systems, and devices for polynucleotide processing. Such polynucleotide processing may be useful for a variety of applications, including polynucleotide sequencing.


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Jordan J N Tang, Arun K Ghosh: Inhibitors of Memapsin 2 and use thereof. The Board of Trustees of the University of Illinois, Oklahoma Medical Research Foundation, Morrison & Foerster, March 16, 2010: US07678760 (4 worldwide citation)

Methods for the production of purified, catalytically active, recombinant memapsin 2 have been developed. The substrate and subsite specificity of the catalytically active enzyme have been determined. The substrate and subsite specificity information was used to design substrate analogs of the natur ...


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Gregory Thomas Bourne, Ashok Bhandari, Xiaoli Cheng, Brian Troy Frederick, Jie Zhang, Dinesh V Patel, David Liu: Oral peptide inhibitors of interleukin-23 receptor and their use to treat inflammatory bowel diseases. Protagonist Therapeutics, Cooley, April 18, 2017: US09624268 (4 worldwide citation)

Peptide inhibitors of the interleukin-23 receptor, and related compositions and methods of using these peptide inhibitors to treat or prevent a variety of diseases and disorders, including inflammatory bowel disease are described.


64
Jeffery A Whiteford, William Freeman, Joshua W Kriesel: Bridged macrocyclic module compositions. May 22, 2012: US08182695 (4 worldwide citation)

This invention is related to the fields of organic chemistry and nanotechnology. In particular, it relates to materials and methods for the preparation of organic synthons and bridged macrocyclic module compounds. The bridged macrocyclic module compounds may be used to prepare macrocyclic compositio ...


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Jan M R Balzarini, Erik D A De Clercq, Antonin Holy, Dana Hockova: Phosphonate substituted pyrimidine compounds and methods for therapy. Institute of Organic Chemistry, Biochemistry of the Academy of Sciences of the Czech Republic, Mark L Bosse, October 3, 2006: US07115592 (4 worldwide citation)

Novel compounds are provided having formula (I) where R1, R2, R3, R4, Z, X and * are defined herein. Also provided are antiviral methods for use and processes for synthesis of the compounds of formula (I).


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Bryant Henry Uhlman, Crowell Thomas Alan, Jones Charles David: Naphthalene compounds, intermediates, formulations, and methods. Lilly Co Eli, March 4, 1998: EP0826670-A1 (4 worldwide citation)

This invention relates to the field of pharmaceutical and organic chemistry and provides naphthalene compounds, intermediates, formulations, and methods. The naphthalene compounds have the formula: wherein R is -H, -OH, -O(C1-C4 alkyl), -OCO(C1-C6 alkyl), -O-CO-O(C1-C6 alkyl), -O-CO-Ar, -OSO2(C2-C6 ...


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Yun xiang Zhang, Xing yi Dai, Zhi kang Lu, Sen Zeng: Process for preparing a terpolymer of tetrafluoroethylene, ethylene and a third monomer. Shanghai Institute of Organic Chemistry Academia Sinica, Burns Doane Swecker & Mathis, July 7, 1987: US04678847 (4 worldwide citation)

The present invention relates to the process for preparing terpolymer of tetrafluoroethylene (TFE), ethylene (E), and a third monomer. According to the present invention, dicarbonate peroxide is used as initiator, 1,1,2-trichloro-1,2,2-trifluoro-ethane as the reaction medium and compounds of molecul ...


69
Claude Perrin: New quinolone derivatives, a process for their preparation and the pharmaceutical compositions which contain them. Bouchara, December 23, 1994: FR2706459-A1 (4 worldwide citation)

The invention relates to the field of organic chemistry and in particular to that of therapeutic chemistry. It specifically relates to new 7-hexahydrodiazepinyl-6-fluoroquinolone-3-carboxylic acids of general formula I in which R is hydrogen, an alkyl, an acyl or an aminocarbonyl and R1 is hydrogen, ...


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Bryant Henry U, Dodge Jeffrey A, Nissen Jeffrey S: Phosphorous-containing benzothiophenes. Lilly Co Eli, September 4, 1996: EP0729964-A1 (4 worldwide citation)

This invention relates to the fields of pharmaceutical and organic chemistry and provides novel phosphorous-containing benzothiophene compounds which are useful for the treatment of the various medical indications associated with post-menopausal syndrome, as well as estrogen dependent diseases inclu ...