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Baudry Barbier Denise, Dormond Alain, Richard Stephanie, Bouazza Aicha, Desmurs Jean Roger: A new process for the acylation of an aromatic compound. Rhone Poulenc Chimie, March 26, 1999: FR2768728-A1 (8 worldwide citation)

The use of a uranium and/or uranyl halide as a catalyst for the preparation of acylated aromatic compounds, particularly alkoxyaromatic alkylketones.TF - TECHNOLOGY FOCUS - ORGANIC CHEMISTRY - Preferred Components: The preferred aromatic compound is of general formula (I) : - -A = (i) mono or polyar ...


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Lu Long, Chen Jie, Wu Yong, Jin Zhiping, Xu Xiaoyan, Yuan Jun, Zhang Yan, Wang Yonghua: 2-pyrimidionxy-n-carbamidophenylbenzylamine compounds and processes of the preparation thereof and the use of the same. Shanghai Institute Of Organic Chemistry Chinese Academy Of Sciences, Zhejiang Chem Tech Group, Bayer Cropscience, Lu Long, Chen Jie, Wu Yong, Jin Zhiping, Xu Xiaoyan, Yuan Jun, Zhang Yan, Wang Yonghua, SHANGHAI ZHI XIN PATENT AGENT, July 28, 2005: WO/2005/068434 (8 worldwide citation)

The present invention disclosed a series of 2-pyrimidionxy-N-carbamidophenylbenzylamine compounds and processes of the preparation thereof and the herbicide use of the same. The compounds represented by the following formula (I), wherein D or E is hydrogen, halogen, C1-C4 alkyl, C1-C4 akloxy, C1-C4 ...


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Beigelman Leonid, Blatt Lawrence, Lonnberg Harri: 2-5a analogs and their methods of use. Alios Biopharma, Beigelman Leonid, Blatt Lawrence, Lonnberg Harri, ARNO Thomas R, August 7, 2008: WO/2008/095040 (8 worldwide citation)

This invention relates to the fields of organic chemistry, pharmaceutical chemistry, biochemistry, molecular biology and medicine. In particular it relates to compounds that activate RNaseL, and to the use of the compounds for treating and/or ameliorating a disease or a condition, such as a viral in ...


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Benjamin Hindson, Serge Saxonov, Kevin Ness, Paul Hardenbol, Michael Schnall Levin, Mirna Jarosz: Methods and systems for processing polynucleotides. 10X GENOMICS, Wilson Sonsini Goodrich & Rosati, January 2, 2018: US09856530 (7 worldwide citation)

The present disclosure provides compositions, methods, systems, and devices for polynucleotide processing. Such polynucleotide processing may be useful for a variety of applications, including polynucleotide sequencing.


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Benjamin Hindson, Serge Saxonov, Kevin Ness, Paul Hardenbol, Christopher Hindson, Donald Masquelier, Mirna Jarosz, Michael Schnall Levin: Partitioning and processing of analytes and other species. 10X GENOMICS, Wilson Sonsini Goodrich & Rosati, May 9, 2017: US09644204 (7 worldwide citation)

The present disclosure provides compositions, methods, systems, and devices for polynucleotide processing. Such polynucleotide processing may be useful for a variety of applications, including polynucleotide sequencing.


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Antonin Holy, Ivan Rosenberg, Erik D A De Clercq: 9-(2-phosphonylmethoxyethyl) guanine. Institute of Organic Chemistry and Biochemistry of the Academy of Sciences of the Czech Republic, Rega Stichting v z w, Max D Hensley, February 9, 1999: US05869467 (7 worldwide citation)

This invention relates to new nucleotide analogues and solves the technical problem of their use as biologically active compounds. The subject of this invention are N-(2-phosphonylmethoxyethyl) and N-(3-hydroxy-2-phosphonylmethoxypropyl) derivatives of pyrimidine and purine bases, easily accessible ...


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Erik Christopher Chelius, Susan Marie Reutzel Edens, Sharon Van den Berghe Snorek: Crystalline of N-[4-[2-(2-Amino-4,7-dihydro-4oxo-3H-pyrrolo[2,3-D]pyrimidin-5-YL)ethyl]benzoyl]-L-glutamic acid and process therefor. Eli Lilly and Company, Elizabeth A McGraw, Manisha A Desai, November 21, 2006: US07138521 (7 worldwide citation)

The invention relates to the field of pharmaceutical and organic chemistry and provides an improved process for preparing the novel heptahydrate crystalline salt of multitargeted antifolate N-[4-[2-(2-amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]-pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic acid.


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Leimgruber Willy, Wick Alexander E: Process for the methylenation of catechols. Hoffmann La Roche, Welt Samuel L, Leon Bernard S, Hoffman Frank P, November 25, 1975: US3922285 (7 worldwide citation)

A method for the methylenation of catechols via the reaction of catechols with methylene chloride in the presence of selected strong bases is described. This process has wide applicability in the field of synthetic organic chemistry, especially in natural product syntheses.