31
Vincent F Salvia: Transition metal/polymer matrix composite of transition metal dichalcogenides and polymers a lubricious and wear resistant composite and methods for applying such to substrata. April 18, 1995: US05407590 (10 worldwide citation)

The present invention provides a transition metal/polymer matrix composite material which has durable, wear and corrosion resistant and friction reducing characteristics which can be used in a powder or liquid form, or, which can be bonded to a desired surface at ambient temperature. The specific co ...


32
Yuan Junying, Yuan Chengye, Degterev Alexei: Compounds, screens, and methods of treatment. President And Fellows Of Harvard College, Shanghai Institute Of Organic Chemistry Chinese Academy Of Sciences, Yuan Junying, Yuan Chengye, Degterev Alexei, BIEKER BRADY Kristina, April 17, 2008: WO/2008/045406 (10 worldwide citation)

The present invention features compounds of Formula (I), pharmaceutical compositions, methods of synthesis, and methods for treating diseases and conditions associated with cellular necrosis. Screening assays for identifying compounds useful for treating these conditions are also described.


33

34
Ferrero Maria Teresa Manresa, Mondelo Fernando Calvo: Process for the preparation of (+/-)-14,15-dihydro-(3 beta ,14 alpha ,16 alpha )- 20,21-dinoreburnamenin-14-ol. Covex, May 29, 1987: FR2590572-A1 (9 worldwide citation)

The invention relates to organic chemistry. It relates to a process for the preparation of (+/-)-14,15-dihydro- (3 beta ,14 alpha ,16 alpha )-20,21-dinoreburnamenin-14-ol, of general formula: characterised in that (+/-)(3 beta ,16 alpha )-20,21-eburnamenine is reacted with hydrogen peroxide via an o ...


35
Yuan Junying, Ma Dawei, Zhang Lihong: Autophagy inducing compounds and uses thereof in treating autophagy associated diseases. President And Fellows Of Harvard College, Shanghai Institute Of Organic Chemistry, Yuan Junying, Ma Dawei, Zhang Lihong, DECONTI Giulio A, April 16, 2009: WO/2009/049242 (9 worldwide citation)

This invention pertains to a class of autophagy inducing compounds that treat diseases caused by misfolded protein aggregates and a screening method for identifying these compounds.


36
Fokin Valery, Sharpless Barry K, Wu Peng, Feldman Alina: Click chemistry route to triazole dendrimers. The Scripps Research Institute, Fokin Valery, Sharpless Barry K, Wu Peng, Feldman Alina, FITTING Thomas Lewis Donald G, January 12, 2006: WO/2006/005046 (9 worldwide citation)

The high efficiency and fidelity of click chemistry permits a large number of diverse dendrimers encompassing a wide variety of functionalities at the chain ends, repeat units, and/or core to be prepared. Almost quantitative yields were obtained during the synthesis. In some cases, filtration or sol ...


37
Murray A Rosenthal, Michael E Jackson: Primary standard and method of making secondary standards for calibration of glycated protein assays. Isolab, Roger A Gilcrest, July 21, 1992: US05132230 (8 worldwide citation)

This invention provides a primary standard and/or secondary standards for assay for glycated proteins in samples such as blood. The primary standard is composed of a polymer or copolymer of an amino acid, such as lysine, serine or those listed on table 37 (pages 100-110 of the second edition of Orga ...


38
Baudry Barbier Denise, Dormond Alain, Richard Stephanie, Bouazza Aicha, Desmurs Jean Roger: A new process for the acylation of an aromatic compound. Rhone Poulenc Chimie, March 26, 1999: FR2768728-A1 (8 worldwide citation)

The use of a uranium and/or uranyl halide as a catalyst for the preparation of acylated aromatic compounds, particularly alkoxyaromatic alkylketones.TF - TECHNOLOGY FOCUS - ORGANIC CHEMISTRY - Preferred Components: The preferred aromatic compound is of general formula (I) : - -A = (i) mono or polyar ...


39
Antonin Holy, Ivan Rosenberg, Erik D A De Clercq: 9-(2-phosphonylmethoxyethyl) guanine. Institute of Organic Chemistry and Biochemistry of the Academy of Sciences of the Czech Republic, Rega Stichting v z w, Max D Hensley, February 9, 1999: US05869467 (7 worldwide citation)

This invention relates to new nucleotide analogues and solves the technical problem of their use as biologically active compounds. The subject of this invention are N-(2-phosphonylmethoxyethyl) and N-(3-hydroxy-2-phosphonylmethoxypropyl) derivatives of pyrimidine and purine bases, easily accessible ...


40
Erik Christopher Chelius, Susan Marie Reutzel Edens, Sharon Van den Berghe Snorek: Crystalline of N-[4-[2-(2-Amino-4,7-dihydro-4oxo-3H-pyrrolo[2,3-D]pyrimidin-5-YL)ethyl]benzoyl]-L-glutamic acid and process therefor. Eli Lilly and Company, Elizabeth A McGraw, Manisha A Desai, November 21, 2006: US07138521 (7 worldwide citation)

The invention relates to the field of pharmaceutical and organic chemistry and provides an improved process for preparing the novel heptahydrate crystalline salt of multitargeted antifolate N-[4-[2-(2-amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]-pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic acid.



Click the thumbnails below to visualize the patent trend.