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James Doherty
Dorn Conrad P, Finke Paul E, Maccoss Malcolm, Doherty James B, Shah Shrenik K, Hagmann William K: New substituted azetidinones as anti-inflammatory and antidegenerative agents.. Merck & Co, April 22, 1992: EP0481671-A1 (40 worldwide citation)

New substituted azetidinones of the general formula (A') which have been found to be potent elastase inhibitors and thereby useful anti-inflammatory and antidegenerative agents are described. e


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Doherty James B, Finke Paul E, Dorn Conrad P, Maccoss Malcolm, Durette Philippe L, Mills Sander G, Shah Shrenik K, Lanza Thomas J, Sahoo Soumya P, Hagmann William K, Hale Jeffrey J: New substituted azetidinones as anti-inflammatory and antidegenerative agents.. Merck & Co, May 4, 1994: EP0595557-A1 (3 worldwide citation)

Substituted azetidinones of the general Formula (I) which have been found to be potent elastase inhibitors and thereby useful anti-inflammatory and antidegenerative agents, wherein R4 is (a) b) where Rx is carboxy C1-6alkyl, benzyloxycarbonylC1-3alkyl, or t-butoxycarbonylC1-3alkyl, wherein Q is a co ...


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Maccoss Malcolm, Durette Philippe L: New substituted azetidinones as anti-inflammatory and antidegenerative agents.. Merck & Co, September 23, 1992: EP0505095-A2

New substituted azetidinones of the general formula (A), which have been found to be potent elastase inhibitors and thereby useful as anti-inflammatory and antidegenerative agents, are described.


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Maccoss Malcolm, Durette Philippe L: New substituted azetidinones as anti-inflammatory and antidegenerative agents.. Merck & Co, September 23, 1992: EP0505097-A2

New substituted azetidinones of the general formula (A), which have been found to be potent elastase inhibitors and thereby useful as anti-inflammatory and antidegenerative agents, are described.


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James B Doherty, Conrad P Dorn, Philippe L Durette: New substituted azetidinones as anti-inflammatory and antidegenerative agents. Merck &Amp Co, TIAN MINGSHENG WANG JINGCHAO, August 3, 1994: CN93119648

Substituted azetidinones of general formula (I) which have been found to be potent elastase inhibitors and thereby useful anti-inflammatory and antidegenerative agents, wherein R1, R2, R3, R4, Ra, Rb and M are defined in the description.


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Doherty James P, Dorn Conrad P, Durette Philippe L, Finke Paul E, Maccoss Malcom, Mills Sander G, Shah Shrenik K, Sahoo Soumya P, Hale Jeffrey J, Lanza Thomas J, Hagmann William K: New substituted azetidinones as anti-inflammatory and antidegenerative agents. Merck & Co, Doherty James P, Dorn Conrad P, Durette Philippe L, Finke Paul E, Maccoss Malcom, Mills Sander G, Shah Shrenik K, Sahoo Soumya P, Hale Jeffrey J, Lanza Thomas J, Hagmann William K, DANIEL Mark R, May 11, 1994: WO/1994/010142

Substituted azetidinones of general formula (I) which have been found to be potent elastase inhibitors and thereby useful anti-inflammatory and antidegenerative agents, wherein: R¿4? is (a) or (b) where R¿x? is carboxy C¿1-6?alkyl, benzyloxycarbonylC¿1-3?alkyl, or t-butoxycarbonylC¿1-3?alkyl, wherei ...


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Doherty James B, Dorn Conrad P, Durette Philippe L, Finke Paul E, Maccoss Malcolm, Mills Sander G, Shah Shrenik K, Sahoo Soumya P, Polo Scott A, Hagmann William K: New substituted azetidinones as anti-inflammatory and antidegenerative agents.. Merck & Co, August 16, 1995: EP0666846-A1

New substituted azetidinones of general formula (I) which have been found to be potent elastase inhibitors and thereby useful anti-inflammatory and antidegenerative agents are described.



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