1
James P Tam: Multiple antigen peptide system. The Rockefeller University, Wyatt Gerber Burke and Badie, July 20, 1993: US05229490 (191 worldwide citation)

Multiple antigen peptide systems are described in which a large number of antigens are bound to the functional groups of a dendritic core molecule providing a high concentration of antigen in a low molecular volume. The products are useful for producing chemically defined univalent or multivalent va ...


2
James P Tam: Multiple antigen peptide system having adjuvant properties, vaccines prepared therefrom and methods of use thereof. Klauber & Jackson, December 3, 1996: US05580563 (60 worldwide citation)

A multiple antigenic peptide system is disclosed that comprises a dendritic core and peptide and a lipophilic anchoring moiety. This particular combination has as an advantage that it eliminates the need for the inclusion of adjuvants found to be toxic to humans, and facilitates the exponential ampl ...


3
SOLOMON BEKA: [fr] Composition immunisante et procédé permettant dinduire une réponse immunitaire contre le site de clivage de la bêta-sécrétase, [de] Immunisierende zusammensetzung und verfahren zur auslösung einer immunantwort gegen die beta-secretase-cleavage-stelle von amyloid-vorläuferprotein, [en] Immunizing composition and method for inducing an immune response against the beta-secretase cleavage site of amyloid precursor protein. UNIV RAMOT, March 9, 2011: EP2292247-A2

[en] The present invention is directed to an immunizing composition containing an antigenic product such as a multiple antigen peptide system (MAPS) or a filamentous bacteriophage displaying an APP epitope spanning the -secretase cleavage site of APP and a method for inducing an immune response agai ...


4
Beka Solomon: Immunizing composition and method for inducing an immune response against the β-secretase cleavage site of amyloid precursor protein. Ramot at Tel Aviv University, Browdy and Neimark PPLC, December 24, 2013: US08613928

The present invention is directed to an immunizing composition containing an antigenic product such as a multiple antigen peptide system (MAPS) or a filamentous bacteriophage displaying an AβPP epitope spanning the β-secretase cleavage site of AβPP and a method for inducing an immune response agains ...


5
Beka Solomon: Immunizing composition and method for inducing an immune response against the β-secretase cleavage site of amyloid precursor protein. Ramot at Tel Aviv University, Browdy and Neimark P L L C, February 24, 2009: US07494655

The present invention is directed to an immunizing composition containing an antigenic product such as a multiple antigen peptide system (MAPS) or a filamentous bacteriophage displaying an AβPP epitope spanning the β-secretase cleavage site of AβPP and a method for inducing an immune response agains ...


6
Beka Solomon: Immunizing compostion and method for inducing an immune response against the beta-secretase cleavage site of amyloid precursor protein. Ramot At Tel Aviv University, Browdy and Neimark PLLC, December 21, 2010: US07854931

The present invention is directed to an immunizing composition containing an antigenic product such as a multiple antigen peptide system (MAPS) or a filamentous bacteriophage displaying an AβPP epitope spanning the β-secretase cleavage site of AβPP and a method for inducing an immune response agains ...


7
John K Fink, Shirley Rainier, Robert D Nicholls, Jinghua Chai: Compositions and methods for detecting and treating neurological conditions. The Regents of the University of Michigan, The Trustees of the University of Pennsylvania, Casimir Jones SC, January 16, 2018: US09868990

The present invention relates to the NIPA-1 proteins and nucleic acids encoding the NIPA-1 proteins. The present invention further provides assays for the detection of NIPA-1 polymorphisms and mutations associated with disease states, as well as methods of screening for ligands and modulators of NIP ...


8
Hiroaki Matsunami, Yun Li: Compositions and methods for enhancing odorant receptor activity. DUKE UNIVERSITY, Casimir Jones SC, April 4, 2017: US09611308

The present invention relates to polypeptides capable of modulating odorant receptor activation. In particular, the present invention provides polypeptides (e.g., type 3 muscarinic actetylcholine receptor M3) capable of enhancing odorant receptor activation. The present invention further provides as ...


9
Solomon Beka: Immunizing composition and method for inducing an immune response against the ss-secretase cleavage site of amyloid precursor protein. Univ Ramot, December 1, 2004: EP1480666-A2

The present invention is directed to an immunizing composition containing an antigenic product such as a multiple antigen peptide system (MAPS) or a filamentous bacteriophage displaying an AssPP epitope spanning the ss-secretase cleavage site of AssPP and a method for inducing an immune response aga ...


10
Tam James P, Zavala Fidel P: Dendritic polymer of multiple antigen peptide system useful as anti-malarial vaccine.. Univ Rockefeller, Univ New York, April 24, 1991: EP0423315-A1

Multiple antigen peptide systems are described in which a large number of each of T-cell and B-cell malarial antigens are bound to the functional groups of a dendritic core molecule providing a high concentration of antigen in a low molecular volume. The products elicit a very strong immunogenic res ...