1
Kalyan Handique, Sundaresh N Brahmasandra, Karthik Ganesan, Jeff Williams: Microfluidic system for amplifying and detecting polynucleotides in parallel. HandyLab, Knobbe Martens Olson & Bear, August 16, 2011: US07998708 (74 worldwide citation)

The present technology provides for an apparatus for detecting polynucleotides in samples, particularly from biological samples. The technology more particularly relates to microfluidic systems that carry out PCR on nucleotides of interest within microfluidic channels, and detect those nucleotides. ...


2
Kalyan Handique: Microfluidic cartridge. HandyLab, Knobbe Martens Olson & Bear, January 31, 2012: US08105783 (71 worldwide citation)

The technology described herein generally relates to microfluidic cartridges configured to amplify and detect polynucleotides extracted from multiple biological samples in parallel. The technology includes a microfluidic substrate, comprising: a plurality of sample lanes, wherein each of the plurali ...


3
Kalyan Handique, Sundaresh N Brahmasandra, Karthik Ganesan, Jeff Williams: Microfluidic system for amplifying and detecting polynucleotides in parallel. HandyLab, Knobbe Martens Olson & Bear, December 4, 2012: US08323900 (65 worldwide citation)

The present technology provides for an apparatus for detecting polynucleotides in samples, particularly from biological samples. The technology more particularly relates to microfluidic systems that carry out PCR on nucleotides of interest within microfluidic channels, and detect those nucleotides. ...


4
Kalyan Handique: Microfluidic cartridge. Handylab, Knobbe Martens Olson & Bear, April 9, 2013: US08415103 (56 worldwide citation)

The technology described herein generally relates to microfluidic cartridges configured to amplify and detect polynucleotides extracted from multiple biological samples in parallel. The technology includes a microfluidic substrate, comprising: a plurality of sample lanes, wherein each of the plurali ...


5
Kalyan Handique: Microfluidic cartridge and method of using same. Handylab, Knobbe Martens Olson & Bear, April 29, 2014: US08709787 (55 worldwide citation)

The present technology provides for a microfluidic substrate configured to carry out PCR on a number of polynucleotide-containing samples in parallel. The substrate can be a single-layer substrate in a microfluidic cartridge. Also provided are a method of making a microfluidic cartridge comprising s ...


6
Handique Kaylan, Kehrer Aaron: Containers for liquid storage and delivery with application to microfluidic devices. Handylab, Handique Kaylan, Kehrer Aaron, BONE Richard, July 27, 2006: WO/2006/079082 (52 worldwide citation)

A container (1 ) for a liquid reagent (9), wherein the container has an outer wall (3) and an internal piercing member (6), such that, upon application of pressure to the outer wall of the container, the internal piercing member punctures the container from the inside, thereby liberating the liquid ...


7
Handique Kalyan, Brahmasandra Sundaresh N, Ganesan Karthik, Williams Jeff: Microfluidic system for amplifying and detecting polynucleotides in parallel. Handylab, Handique Kalyan, Brahmasandra Sundaresh N, Ganesan Karthik, Williams Jeff, BONE Richard G A, May 22, 2008: WO/2008/060604 (48 worldwide citation)

The present technology provides for an apparatus for detecting polynucleotides in samples, particularly from biological samples. The technology more particularly relates to microfluidic systems that carry out PCR on nucleotides of interest within microfluidic channels, and detect those nucleotides. ...


8
Handique Kalyan, Brahmasandra Sundaresh N, Ganesan Karthik, Wu Betty, Phadke Nikhil, Parunak Gene, Williams Jeff: Integrated system for processing microfluidic samples, and method of using same. Handylab, Handique Kalyan, Brahmasandra Sundaresh N, Ganesan Karthik, Wu Betty, Phadke Nikhil, Parunak Gene, Williams Jeff, BONE Richard G A, October 4, 2007: WO/2007/112114 (48 worldwide citation)

This patent application describes an integrated apparatus for processing polynucleotide-containing samples, and for providing a diagnostic result thereon. The apparatus is configured to receive a microfluidic cartridge that contains reagents and a network for processing a sample. Also described are ...


9
Cleopatra Cabuz, Eugen Cabuz, David J Zook: Miniaturized flow controller with closed loop regulation. Honeywell International, Kris T Fredrick, June 13, 2006: US07061595 (38 worldwide citation)

An apparatus having scattering and multi-color fluorescence detecting, analyzing and identification capabilities of blood or other fluids of interest. The sample to be tested may be entered in a disposable microfluidic cartridge which in turn is insertable in a hand-holdable or implantable miniaturi ...


10
Aravind Padmanabhan, Bernard S Fritz: Miniaturized cytometer for detecting multiple species in a sample. Honeywell International, Kris T Fredrick, December 8, 2009: US07630063 (35 worldwide citation)

A system for scattered light and simultaneous multi-color (e.g., greater than sixteen colors) fluorescence light detecting, and for analyzing, classifying and identifying biological particles and items of interest. A sample to be tested may be entered in a disposable microfluidic cartridge which in ...