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Denise Demarais, Hanson Gifford III, Mark Deem, Douglas Sutton, Howard R Levin, Mark Gelfand: Methods for renal neuromodulation. Ardian, Perkins Coie, March 27, 2012: US08145317 (229 worldwide citation)

Methods and apparatus are provided for treating hypertension, e.g., via a pulsed electric field, via a stimulation electric field, via localized drug delivery, via high frequency ultrasound, via thermal techniques, etc. Such neuromodulation may effectuate irreversible electroporation or electrofusio ...


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LEUNG Mark S, CLARK Benjamin J, MICHLITSCH Kenneth, THAI Erik, WU Andrew, ZARINS Denise: Appareils et systèmes de type cathéter, et méthodes de neuromodulation rénale, Catheter apparatuses, systems, and methods for renal neuromodulation. Medtronic Ardian, LEUNG Mark S, CLARK Benjamin J, MICHLITSCH Kenneth, THAI Erik, WU Andrew, ZARINS Denise, SHELDON Anthony, November 10, 2011: WO/2011/139589 (45 worldwide citation)

Catheter apparatuses, systems, and methods for achieving renal neuromodulation by intravascular access are disclosed herein. One aspect of the present application, for example, is directed to apparatuses, systems, and methods that incorporate a catheter treatment device comprising an elongated shaft ...


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Andrew Wu, Benjamin J Clark, Denise Zarins, Erik Thai, Kenneth J Michlitsch, Mark S Leung: Multi-directional deflectable catheter apparatuses, systems, and methods for renal neuromodulation. Medtronic Ardian Luxembourg r l, May 20, 2014: US08728075 (19 worldwide citation)

Multi-directional deflectable catheter apparatuses, systems, and methods for achieving renal neuromodulation by intravascular access are disclosed herein. One aspect of the present application, for example, is directed to apparatuses, systems, and methods that incorporate a catheter treatment device ...


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GOSHGARIAN Justin, CLARK Benjamin J, DHAMODHARASAMY Rajeshkumar, LEUNG Mark S, ABOYTES Maria G: APPAREILS, SYSTÈMES ET PROCÉDÉS DE CATHÉTER POUR NEUROMODULATION RÉNALE, CATHETER APPARATUSES, SYSTEMS, AND METHODS FOR RENAL NEUROMODULATION. MEDTRONIC ARDIAN LUXEMBOURG R L, GOSHGARIAN Justin, CLARK Benjamin J, DHAMODHARASAMY Rajeshkumar, LEUNG Mark S, ABOYTES Maria G, POLEDNA Aaron J, April 26, 2012: WO/2012/054906 (4 worldwide citation)

Catheter apparatuses, systems, and methods for achieving renal neuromodulation by intravascular access are disclosed herein. One aspect of the present application, for example, is directed to apparatuses, systems, and methods that incorporate a catheter treatment device comprising an elongated shaft ...


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EMERY Charles D, GELFAND Mark, LEVIN Howard R, ZARINS Denise: APPAREILS À ULTRASONS FOCALISÉS DE HAUTE INTENSITÉ, SYSTÈMES ET PROCÉDÉS DE NEUROMODULATION RÉNALE, HIGH INTENSITY FOCUSED ULTRASOUND APPARATUSES, SYSTEMS, AND METHODS FOR RENAL NEUROMODULATION. MEDTRONIC ARDIAN LUXEMBOURG R L, EMERY Charles D, GELFAND Mark, LEVIN Howard R, ZARINS Denise, KOPCZYNSKI Jeffie A, May 10, 2012: WO/2012/061713 (3 worldwide citation)

Catheter apparatuses, systems, and methods for achieving renal neuromodulation by intravascular access are disclosed herein. One aspect of the present application, for example, is directed to apparatuses, systems, and methods that incorporate a catheter treatment device that employs high intensity f ...


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Justin Goshgarian, Benjamin J Clark, Rajeshkumar Dhamodharasamy, Mark S Leung, Maria G Aboytes: Catheter apparatuses, systems, and methods for renal neuromodulation. Medtronic Ardian Luxembourg r l, July 21, 2015: US09084610 (2 worldwide citation)

Catheter apparatuses, systems, and methods for achieving renal neuromodulation by intravascular access are disclosed herein. One aspect of the present application, for example, is directed to apparatuses, systems, and methods that incorporate a catheter treatment device comprising an elongated shaft ...


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Mark Deem, Denise Zarins, Douglas Sutton, Hanson Gifford III, Howard R Levin, Mark Gelfand, Benjamin J Clark: Methods for renal neuromodulation. Medtronic Ardian Luxembourg r l, November 17, 2015: US09186213 (1 worldwide citation)

Methods and apparatus are provided for renal neuromodulation using a pulsed electric field to effectuate electroporation or electrofusion. It is expected that renal neuromodulation (e.g., denervation) may, among other things, reduce expansion of an acute myocardial infarction, reduce or prevent the ...