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Michael D Leach, Jennifer E Woodell May, Joel C Higgins, Krista O Shaughnessey: Methods for making cytokine compositions from tissues using non-centrifugal methods. Biomet Biologies, Schwegman Lundberg & Woessner P A, January 31, 2017: US09556243 (1 worldwide citation)

Apparatus and methods for generating a solution rich in interleukin-1 receptor antagonist from a tissue comprising cytokine-producing cells. The apparatus can include a filter used with a separation system. The separation system can include a float.


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Methods for Making Cytokine Compositions From Tissues Using Non-Centrifugal Methods. Biomet Biologics, September 18, 2014: US20140275497-A1

Apparatus and methods for generating a solution rich in interleukin-1 receptor antagonist from a tissue comprising cytokine-producing cells. The apparatus can include a filter used with a separation system. The separation system can include a float.


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METHODS FOR MAKING CYTOKINE COMPOSITIONS FROM TISSUES USING NON-CENTRIFUGAL METHODS. BIOMET BIOLOGICS, September 18, 2014: US20140274894-A1

Non-centrifugal methods for generating a solution rich in interleukin-1 receptor antagonist from a tissue comprising cytokine-producing cells. The solution rich in IL-1ra can also include at least one of sTNF-RI, sTNF-RII, IGF-I, EGF, HGF, PDGF-AB, PDGF-BB, VEGF, TGF-β1, and sIL-1 RII.