1
Richard Sackler, Robert Kaiko, Paul Goldenheim: Method of treating humans with opioid formulations having extended controlled release. Purdue Pharma, Davidson Davidson & Kappel, November 7, 2000: US06143322 (184 worldwide citation)

Solid controlled-release oral dosage forms comprising a therapeutically effective amount of an opioid analgesic or a salt thereof which provide an extended duration of pain relief of about 24 hours, have a dissolution rate in-vitro of the dosage form, when measured by the USP Paddle Method at 100 rp ...


2
Richard Sackler, Robert Kaiko, Paul Goldenheim: Method of treating humans with opioid formulations having extended controlled release. Purdue Pharma, Davidson Davidson & Kappel, June 22, 2010: US07740881 (2 worldwide citation)

Solid controlled-release oral dosage forms comprising a therapeutically effective amount of an opioid analgesic or a salt thereof which provide an extended duration of pain relief of about 24 hours, have a dissolution rate in-vitro of the dosage form, when measured by the USP Paddle Method at 100 rp ...