1
James A Wells, Brian C Cunningham: Method for identifying active domains and amino acid residues in polypeptides and hormone variants. Genentech, Timothy R Schwartz, Diane L Marschang, November 10, 1998: US05834250 (98 worldwide citation)

The invention provides methods for the systematic analysis of the structure and function of polypeptides by identifying active domains which influence the activity of the polypeptide with a target substance. Such active domains are determined by substituting selected amino acid segments of the polyp ...


2
James A Wells, Brian C Cunningham: Method for identifying active domains and amino acid residues in polypeptides and hormone variants. Genetech, Laura Terlizzi, Emily M Haliday, Skjerven Morrill MacPherson Franklin & Friel, December 3, 1996: US05580723 (87 worldwide citation)

The invention provides methods for the systematic analysis of the structure and function of polypeptides by identifying active domains which influence the activity of the polypeptide with a target substance. Such active domains are determined by substituting selected amino acid segments of the polyp ...


3
James A Wells, Brian C Cunningham: Method for identifying active domains and amino acid residues in polypeptides and hormone variants. Genentech, Timothy R Schwartz, January 11, 2000: US06013478 (68 worldwide citation)

The invention provides methods for the systematic analysis of the structure and function of polypeptides by identifying active domains which influence the activity of the polypeptide with a target substance. Such active domains are determined by substituting selected amino acid segments of the polyp ...


4
James A Wells, Brian C Cunningham: Method for identifying active domains and amino acid residues in polypeptides and hormone variants. Genentech, Gates & Cooper, August 6, 2002: US06428954 (50 worldwide citation)

The invention provides methods for the systematic analysis of the structure and function of polypeptides by identifying active domains which influence the activity of the polypeptide with a target substance. Such active domains are determined by substituting selected amino acid segments of the polyp ...


5
Wells James A, Cunningham Brian C: Method for identifying active domains and amino acid residues in polypeptides and hormone variants.. Genentech, November 22, 1990: EP0397834-A1 (8 worldwide citation)

The invention provides methods for the systematic analysis of the structure and function of polypeptides by identifying active domains which influence the activity of the polypeptide with a target substance. Such active domains are determined by substituting selected amino acid segments of the polyp ...


6
James A Wells, Brian C Cunningham: Method for identifying active domains and amino acid residues in polypeptides and hormone variants. Genentech, Laura Terlizzi, Emily M Haliday, Skjerven Morrill MacPherson Franklin & Friel, June 16, 1998: US05766854

The invention provides methods for the systematic analysis of the structure and function of polypeptides by identifying active domains which influence the activity of the polypeptide with a target substance. Such active domains are determined by substituting selected amino acid segments of the polyp ...


7
Wells James A, Cunningham Brian C: Methode didentification des domaines actifs et des residus dacides amines dans les variants de polypeptides et dhormones, Method for identifying active domains and amino acid residues in polypeptides and hormone variants. Genentech, Genentech, SMART & BIGGAR, October 16, 2001: CA2001774

The invention provides methods for the systematicanalysis of the structure and function ofpolypeptides by identifying active domains whichinfluence the activity of the polypeptide with atarget substance. Such active domains are determinedby substituting selected amino acid segments of thepolypeptide ...


8
Wells James A, Cunningham Brian C: Method for identifying active domains and amino acid residues in polypeptides and hormone variants. Genentech, TRECARTIN Richard F, May 3, 1990: WO/1990/004788

The invention provides methods for the systematic analysis of the structure and function of polypeptides by identifying active domains which influence the activity of the polypeptide with a target substance. Such active domains are determined by substituting selected amino acid segments of the polyp ...