1
Toufike Kanouni
Qing Dong, Toufike Kanouni, Michael B Wallace: MAPK/ERK kinase inhibitors. Takeda Pharmaceutical Company, David M Stemerick, Mitchell R Brustein, September 20, 2011: US08022057 (1 worldwide citation)

Compounds of the following formula are provided for use with MEK: wherein the variables are as defined herein. Also provided are pharmaceutical compositions, kits and articles of manufacture comprising such compounds; methods and intermediates useful for making the compounds; and methods of using sa ...


2
Toufike Kanouni
Qing Dong, Xianchang Gong, Stephen W Kaldor, Toufike Kanouni, Nicholas Scorah, Michael B Wallace, Feng Zhou: MAPK/ERK KINASE INHIBITORS. TAKEDA PHARMACEUTICAL COMPANY, TAKEDA SAN DIEGO, May 27, 2010: US20100130518-A1

Compounds of the following formula are provided for use with MEK (I): wherein the variables are as defined herein. Also provided are pharmaceutical compositions, kits and articles of manufacture comprising such compounds; methods and intermediates useful for making the compounds; and methods of usin ...


3
Toufike Kanouni
Qing Dong, Xianchang Gong, Stephen W Kaldor, Toufike Kanouni, Nicholas Scorah, Michael B Wallace, Feng Zhou: Mapk/erk kinase inhibitors. Takeda San Diego, October 16, 2008: US20080255160-A1

Compounds of the following formula are provided for use with MEK: wherein the variables are as defined herein. Also provided are pharmaceutical compositions, kits and articles of manufacture comprising such compounds; methods and intermediates useful for making the compounds; and methods of using sa ...


4
Toufike Kanouni
MarK Adams, Qing Dong, Toufike Kanouni, Stephen W Kaldor, Nicholas Scorah, Michael B Wallace: Mapk/erk kinase inhibitors. Takeda Pharmaceutical Company, Takeda San Diego, May 14, 2009: US20090124595-A1

Compounds of the following formula are provided for use with MEK: wherein the variables are as defined herein. Also provided are pharmaceutical compositions, kits and articles of manufacture comprising such compounds; methods and intermediates useful for making the compounds; and methods of using sa ...


5
Dong Qing, Jin Bohan: Mapk/erk kinase inhibitors and methods of use thereof. Takeda Pharmaceutical Company, Dong Qing, Jin Bohan, Stemerick David, Weitz David J, Brustein Mitchell R, Smith C Amy, December 3, 2009: WO/2009/146034 (7 worldwide citation)

Compounds of the following formula are provided: wherein the variables are as defined herein. Also provided are pharmaceutical compositions, kits and articles of manufacture comprising such compounds; methods and intermediates useful for making the compounds; and methods of using said compounds.


6
Adams Mark E, Dong Qing, Kaldor Stephen W, Kanouni Toufike, Wallace Michael B: Mapk/erk kinase inhibitors. Takeda Pharmaceutical Company, Adams Mark E, Dong Qing, Kaldor Stephen W, Kanouni Toufike, Wallace Michael B, WEITZ David J, May 8, 2008: WO/2008/055236 (3 worldwide citation)

Compounds, pharmaceutical compositions, kits and methods are provided for use with MEK that comprise a compound selected from the group consisting of wherein the variables are as defined herein.


7
Dong Qing, Gong Xianchang, Kaldor Stephen W, Kanouni Toufike, Scorah Nicholas, Wallace Michael B, Zhou Feng: Mapk/erk kinase inhibitors. Takeda Pharmaceutical Company, Dong Qing, Gong Xianchang, Kaldor Stephen W, Kanouni Toufike, Scorah Nicholas, Wallace Michael B, Zhou Feng, WEITZ David J, July 3, 2008: WO/2008/079814 (3 worldwide citation)

Compounds of the following formula are provided for use with MEK (I): wherein the variables are as defined herein. Also provided are pharmaceutical compositions, kits and articles of manufacture comprising such compounds; methods and intermediates useful for making the compounds; and methods of usin ...


8
Qing Dong, Stephen W Kaldor: MAPK/ERK kinase inhibitors. Takeda Pharmaceutical Company, David M Stemerick, Mitchell R Brustein, October 4, 2011: US08030317 (1 worldwide citation)

Compounds of the following formula are provided for use with MEK: wherein the variables are as defined herein. Also provided are pharmaceutical compositions, kits and articles of manufacture comprising such compounds; methods and intermediates useful for making the compounds; and methods of using sa ...


9
Dong Qing, Feher Victoria, Kaldor Stephen W, Tomita Naoki: Mapk/erk kinase inhibitors. Takeda Pharmaceutical Company, Dong Qing, Feher Victoria, Kaldor Stephen W, Tomita Naoki, WEITZ David J, November 20, 2008: WO/2008/140553 (1 worldwide citation)

Compounds, pharmaceutical compositions, kits and methods are provided for use with MEK that comprise a compound selected from the group consisting of : wherein the variables are as defined herein.


10
Dong Qing, Kanouni Toufike, Wallace Michael B: Mapk/erk kinase inhibitors. Takeda Pharmaceutical Company, Dong Qing, Kanouni Toufike, Wallace Michael B, BRUSTEIN Mitchell R, September 25, 2008: WO/2008/115890 (1 worldwide citation)

Compounds are provided for use with MEK that comprise: formula (I) wherein the variables are as defined herein. Also provided are pharmaceutical compositions, kits and articles of manufacture comprising such compounds; methods and intermediates useful for making the compounds; and methods of using s ...