1
Robert E Fischell, Tim A Fischell: Intra-arterial stent with the capability to inhibit intimal hyperplasia. Medical Innovative Technologies R & D Partnership, October 22, 1991: US05059166 (351 worldwide citation)

Intra-arterial stents are frequently used subsequent to balloon angioplasty to maintain arterial patency. The most frequent cause for failure to maintain patency is the rapid growth of the injured arterial tissue through the openings in the stent, which rapid growth is called "intimal hyperplasia." ...


2
Fischell Robert E, Fischell Tim A: Intra-arterial stent with the capability to inhibit intimal hyperplasia.. Fischell Robert, Fischell Tim A, June 19, 1991: EP0433011-A1 (59 worldwide citation)

A stent, preferably a helical wire (10), is provided for insertion into an artery (AW) following balloon angioplasty or atherectomy and which incorporates or is coated with a radioisotope and is therefore radioactive and provides a source of radiation (12) in situ to prevent restenosis.


3
Fischell Robert E, Fischell Tim A: Drain tuteur intra-arteriel ayant la capacite dinhiber lhyperplasie interne, Intra-arterial stent with the capability to inhibit intimal hyperplasia. Fischell Robert E, Fischell Tim A, Cordis Corporation, GOWLING LAFLEUR HENDERSON, October 24, 2000: CA2031891

It is well known that radiation therapy can reduce the proliferation of rapidly growingcancer cells in a malignant tumor. The present invention utilizes a radioisotope which isintegral to an arterial stent which can irradiate the tissue in close proximity to theimplantation site of the stent in orde ...