41
Kawaoka Yoshihiro, Hatta Masato: Neuraminidase-deficient live influenza vaccines. Kawaoka Yoshihiro, Hatta Masato, STEFFEY Charles E, December 4, 2008: WO/2008/147496 (4 worldwide citation)

Attenuated, neuraminidase deficient influenza virus, and compositions and methods to prepare that virus, are provided.


42
Tsai Theodore F, Trusheim Heidi: Making influenza virus vaccines without using eggs. Novartis, Tsai Theodore F, Trusheim Heidi, MARSHALL Cameron John, March 20, 2008: WO/2008/032219 (4 worldwide citation)

Currently, the steps performed prior to release of influenza strains to vaccine manufacturers involve passaging influenza virus through eggs. The invention aims to provide procedures useful in manufacturing influenza vaccines, in which the use of eggs is reduced, and preferably is avoided altogether ...


43
Uytdehaag Alphonsus Gerardus Cornelis Maria, Pau Maria Grazia, Schouten Govert: Production influenza virus vaccines. Crucell Holland, Uytdehaag Alphonsus Gerardus Cornelis Maria, Pau Maria Grazia, Schouten Govert, HATEBOER Guus, April 26, 2007: WO/2007/045674 (4 worldwide citation)

Means and methods for producing mammalian viruses, the method comprising infecting a culture of immortalized human cells with a virus, incubating the culture infected with virus to propagate the virus under conditions that permit growth of t he virus, and to form a virus-containing medium, and remov ...


44
Banzhoff Angelika, Clemens Ralf: Combined influenza vaccines for seasonal and pandemic protection. Novartis, Banzhoff Angelika, Clemens Ralf, Marshall Cameron John, December 17, 2009: WO/2009/150532 (4 worldwide citation)

Current approaches to influenza vaccination focus either on seasonal strains or pandemic strains. Current seasonal vaccines typically include antigens from two influenza A strains (H1N1 and H3N2) and one influenza B strain. Current pandemic vaccines focus on H5N1 influenza A virus strains. It is an ...


45
COUTURE MANON: Chimeric influenza virus-like particles comprising hemagglutinin. MEDICAGO, Sechley Konrad A, December 29, 2010: WO/2010/148511 (4 worldwide citation)

A method for synthesizing chimeric influenza virus-like particles (VLPs) within a plant or a portion of a plant is provided. The method involves expression of chimeric influenza HA in a plant or a portion of a plant. The invention is also directed towards a VLP comprising chimeric influenza HA prote ...


46
Vajdy Michael, O Hagan Derek: Adminstration routes for priming/boosting with influenza vaccines. Novartis Vaccines And Diagnostics, Vajdy Michael, O Hagan Derek, MARSHALL Cameron John, May 10, 2007: WO/2007/052057 (4 worldwide citation)

Patients receive a mucosal influenza vaccine and then receive a parenteral influenza vaccine, in that order, typically during different visits to a vaccination centre.


47
Jens Peter Gregersen: Decreasing potential iatrogenic risks associated with influenza vaccines. Amy Hessler, Otis Littlefield, Robert J Gorman, February 21, 2012: US08119337 (3 worldwide citation)

Influenza viruses for use in preparing human vaccines have traditionally been grown on embryonated hen eggs, although more modern techniques grow the virus in mammalian cell culture e.g. on Vero, MDCK or PER.C6 cell lines. The inventor has realized that the conditions used for influenza virus 5 cult ...


48
HOFFMAN ERICH, JIN HONG, LU BIN, DUKE GREG, KEMBLE GEORGE WILLIAM: SYSTEME MULTIPLASMIDE DE PRODUCTION DE VIRUS INFLUENZA, MULTI PLASMID SYSTEM FOR THE PRODUCTION OF INFLUENZA VIRUS. MEDIMMUNE VACCINES, MEDIMMUNE VACCINES, FETHERSTONHAUGH & CO, September 17, 2013: CA2482946 (3 worldwide citation)

Vectors and methods for the production of influenza viruses suitable as recombinant influenza vaccines in cell culture are provided. Bi-directional expression vectors for use in a multi-plasmid influenza virus expression system are provided.


49
Minke Jules Maarten, Karaca Kemal, Yao Jiansheng: Canine influenza vaccines. Merial, Minke Jules Maarten, Karaca Kemal, Yao Jiansheng, JARECKI BLACK PHD JD Judy, March 1, 2007: WO/2007/024947 (3 worldwide citation)

The present invention encompasses influenza vaccines, in particular canine influenza vaccines. The vaccine may be a recombinant poxvirus vaccine or an inactivated vaccine. The invention also encompasses recombinant poxvirus vectors encoding and expressing influenza antigens, epitopes or immunogens w ...


50
Couture Manon, Vézina Louis Philippe, Landry Nathalie: New influenza virus immunizing epitope. Medicago, Couture Manon, Vézina Louis Philippe, Landry Nathalie, Ogilvy Renault Sencrl, January 21, 2010: WO/2010/006452 (3 worldwide citation)

A method for synthesizing influenza virus-like particles (VLPs) within a plant or a portion of a plant is provided. The method involves expression of a novel influenza HA protein in plants and its purification The invention is also directed towards a VLP comprising influenza HA protein and plants li ...



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