41
Maria Grazia Pau, Alphonsus G C M UytdeHaag, Govert Johan Schouten: Production of vaccines. Crucell Holland, TraskBritt, May 5, 2009: US07527961 (5 worldwide citation)

Means and methods for producing mammalian viruses, the method comprising infecting a culture of immortalized human cells with a virus, incubating the culture infected with virus to propagate the virus under conditions that permit growth of the virus, and to form a virus-containing medium, and removi ...


42
Hibberd Patricia, Gorbach Sherwood, Snydman David, Goldin Barry: Compositions and methods for enhancing the efficacy of vaccines. New England Medical Center Hospitals, Tufts University, Hibberd Patricia, Gorbach Sherwood, Snydman David, Goldin Barry, CREWS Lee, November 23, 2006: WO/2006/124630 (5 worldwide citation)

This invention concerns compositions for enhancing the efficacy of vaccines such as influenza vaccines. Also included are kits that include these compositions and methods of using the compositions and kits to treat a subject.


43
D Aoust Marc André, Couture Manon, Ors Frédéric, Trépanier Sonia, Lavoie Pierre Olivier, Dargis Michèle, Vézina Louis Philippe, Landry Nathalie: (vlps) Produced in transgenic plants expressing hemagglutinin. Medicago, D Aoust Marc André, Couture Manon, Ors Frédéric, Trépanier Sonia, Lavoie Pierre Olivier, Dargis Michèle, Vézina Louis Philippe, Landry Nathalie, SECHLEY Konrad A, June 25, 2009: WO/2009/076778 (5 worldwide citation)

A method for synthesizing influenza virus-like particles (VLPs) within a plant or a portion of a plant is provided. The method involves expression of influenza HA in plants and the purification by size exclusion chromatography. The invention is also directed towards a VLP comprising influenza HA pro ...


44
Maria G Pau, Alphonsus G C M UytdeHaag, Govert J Schouten: Production of vaccines. Crucell Holland, TraskBritt, June 21, 2011: US07964198 (4 worldwide citation)

Means and methods for producing mammalian viruses, the method comprising infecting a culture of immortalized human cells with a virus, incubating the culture infected with virus to propagate the virus under conditions that permit growth of the virus, and to form a virus-containing medium, and removi ...


45
Maria Grazia Pau, Alphonsus G C M UytdeHaag: Production of vaccines. Crucell Holland, TraskBritt, June 23, 2009: US07550284 (4 worldwide citation)

Means and methods are provided for the production of mammalian viruses comprising: infecting a culture of immortalized human cells with the virus, incubating the culture infected with virus to propagate the virus under conditions that permit growth of the virus, and to form a virus-containing medium ...


46
Maria G Pau, Alphonsus G C M UytdeHaag, Govert J Schouten: Production of vaccines. Crucell Holland, TraskBritt, April 21, 2009: US07521220 (4 worldwide citation)

Means and methods for producing mammalian viruses, the method comprising infecting a culture of immortalized human cells with a virus, incubating the culture infected with virus to propagate the virus under conditions that permit growth of the virus, and to form a virus-containing medium, and removi ...


47
Julien Peetermans, Michele Lobmann, Jean Marie Prevost, Emil Vascoboinic: Live influenza type B virus vaccines and preparation thereof. Recherche et Industrie Therapeutiques, Alan D Lourie, William H Edgerton, June 8, 1976: US03962423 (4 worldwide citation)

Attenuated stable influenza type B virus strains are obtained by recombining a vaccinal and previously attenuated influenza type B virus strain with an influenza type B virus isolate having the desired serotype and isolating a recombinant having at least one marker property of the attenuated parent ...


48
Kawaoka Yoshihiro, Hatta Masato: Neuraminidase-deficient live influenza vaccines. Kawaoka Yoshihiro, Hatta Masato, STEFFEY Charles E, December 4, 2008: WO/2008/147496 (4 worldwide citation)

Attenuated, neuraminidase deficient influenza virus, and compositions and methods to prepare that virus, are provided.


49
Vajdy Michael, O Hagan Derek: Adminstration routes for priming/boosting with influenza vaccines. Novartis Vaccines And Diagnostics, Vajdy Michael, O Hagan Derek, MARSHALL Cameron John, May 10, 2007: WO/2007/052057 (4 worldwide citation)

Patients receive a mucosal influenza vaccine and then receive a parenteral influenza vaccine, in that order, typically during different visits to a vaccination centre.


50
D AOUST MARC ANDRE, COUTURE MANON, ORS FREDERIC, TREPANIER SONIA, LAVOIE PIERRE OLIVIER, DARGIS MICHELE, VEZINA LOUIS PHILIPPE, LANDRY NATHALIE: PSEUDO-PARTICULES DU VIRUS DE LA GRIPPE (VLP) COMPRENANT DE LHEMAGGLUTININE (HA) PRODUIT DANS UNE PLANTE, INFLUENZA VIRUS-LIKE PARTICLES (VLPS) COMPRISING HEMAGGLUTININ PRODUCED WITHIN A PLANT. MEDICAGO, MEDICAGO, GOWLING LAFLEUR HENDERSON, September 24, 2013: CA2693956 (4 worldwide citation)

A method for synthesizing influenza virus--like particles (VLPs) within a plant or a portion of a plant is provided. The method involves expression of influenza HA in plants and the purification by size exclusion chromatography. The invention is also directed towards a VLP comprising influenza HA pr ...



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