31
Contorni Mario: Influenza vaccine with reduced amount of oil-in-water emulsion as adjuvant. Novartis Vaccines And Diagnostics, Contorni Mario, MARSHALL Cameron John, May 10, 2007: WO/2007/052155 (6 worldwide citation)

Influenza vaccines with oil-in-water emulsion adjuvants are known. The amount of emulsion adjuvant required for an influenza vaccine can be reduced, thereby allowing more vaccines to be made from a given amount of emulsion, and/or minimizing the amount of emulsion that has to be produced for a given ...


32
Ben Yedidia Tamar, Singer Yossi: Multimeric multiepitope influenza vaccines. Biondvax Pharmaceuticals, Ben Yedidia Tamar, Singer Yossi, WEBB PO Box 2189 76121 Rehovot, February 5, 2009: WO/2009/016639 (6 worldwide citation)

The present invention relates to multimeric multi-epitope peptide-based vaccines. In particular, the present invention relates to the use of multimeric multi-epitope peptide-based vaccines eliciting protective immunity to influenza.


33
George Kemble, Gregory Duke: Multi plasmid system for the production of influenza virus. Medimmune, Grant Anderson, January 10, 2012: US08093033 (5 worldwide citation)

Vectors and methods for the production of influenza viruses suitable as recombinant influenza vaccines in cell culture are provided. Bi-directional expression vectors for use in a multi-plasmid influenza virus expression system are provided. Additionally, the invention provides methods of producing ...


34
Maria Grazia Pau, Alphonsus G C M UytdeHaag, Govert Johan Schouten: Production of vaccines. Crucell Holland, TraskBritt, May 5, 2009: US07527961 (5 worldwide citation)

Means and methods for producing mammalian viruses, the method comprising infecting a culture of immortalized human cells with a virus, incubating the culture infected with virus to propagate the virus under conditions that permit growth of the virus, and to form a virus-containing medium, and removi ...


35
Rappuoli Rino, O Hagan Derek, Del, Giudice Giuseppe: Influenza vaccines including combinations of particulate adjuvants and immunopotentiators. Novartis Vaccines And Diagnostics, Rappuoli Rino, O Hagan Derek, Del, Giudice Giuseppe, MARSHALL Cameron John, May 10, 2007: WO/2007/052058 (5 worldwide citation)

Influenza vaccines containing insoluble particulate adjuvants have been found to elicit an IgG response that is primarily a TH2 response (IgGl). This response can be shifted towards a THl response (IgG2a) by including immunopotentiators in the compositions. Thus the invention provides an immunogenic ...


36
Hibberd Patricia, Gorbach Sherwood, Snydman David, Goldin Barry: Compositions and methods for enhancing the efficacy of vaccines. New England Medical Center Hospitals, Tufts University, Hibberd Patricia, Gorbach Sherwood, Snydman David, Goldin Barry, CREWS Lee, November 23, 2006: WO/2006/124630 (5 worldwide citation)

This invention concerns compositions for enhancing the efficacy of vaccines such as influenza vaccines. Also included are kits that include these compositions and methods of using the compositions and kits to treat a subject.


37
Maria G Pau, Alphonsus G C M UytdeHaag, Govert J Schouten: Production of vaccines. Crucell Holland, TraskBritt, June 21, 2011: US07964198 (4 worldwide citation)

Means and methods for producing mammalian viruses, the method comprising infecting a culture of immortalized human cells with a virus, incubating the culture infected with virus to propagate the virus under conditions that permit growth of the virus, and to form a virus-containing medium, and removi ...


38
Maria Grazia Pau, Alphonsus G C M UytdeHaag: Production of vaccines. Crucell Holland, TraskBritt, June 23, 2009: US07550284 (4 worldwide citation)

Means and methods are provided for the production of mammalian viruses comprising: infecting a culture of immortalized human cells with the virus, incubating the culture infected with virus to propagate the virus under conditions that permit growth of the virus, and to form a virus-containing medium ...


39
Maria G Pau, Alphonsus G C M UytdeHaag, Govert J Schouten: Production of vaccines. Crucell Holland, TraskBritt, April 21, 2009: US07521220 (4 worldwide citation)

Means and methods for producing mammalian viruses, the method comprising infecting a culture of immortalized human cells with a virus, incubating the culture infected with virus to propagate the virus under conditions that permit growth of the virus, and to form a virus-containing medium, and removi ...


40
Julien Peetermans, Michele Lobmann, Jean Marie Prevost, Emil Vascoboinic: Live influenza type B virus vaccines and preparation thereof. Recherche et Industrie Therapeutiques, Alan D Lourie, William H Edgerton, June 8, 1976: US03962423 (4 worldwide citation)

Attenuated stable influenza type B virus strains are obtained by recombining a vaccinal and previously attenuated influenza type B virus strain with an influenza type B virus isolate having the desired serotype and isolating a recombinant having at least one marker property of the attenuated parent ...



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