1
John W Kozarich, Gary F Musso, Bernard Malfroy Camine: Increasing blood-brain barrier permeability with permeabilizer peptides. Alkermes, Hamilton Brook Smith & Reynolds, December 7, 1993: US05268164 (95 worldwide citation)

Polypeptides called receptor mediated permeabilizers (RMP) increase the permeability of the blood-brain barrier to molecules such as therapeutic agents or diagnostic agents. These receptor mediated permeabilizers are more efficacious than bradykinin in causing the blood-brain barrier to become more ...


2
John W Kozarich, Gary F Musso, Bernard Malfroy Camine: Increasing blood-brain barrier permeability with permeabilizer peptides. Alkermes, Hamilton Brook Smith & Reynolds, April 9, 1996: US05506206 (67 worldwide citation)

Polypeptides called receptor mediated permeabilizers (RMP) increase the permeability of the blood-brain barrier to molecules such as therapeutic agents or diagnostic agents. These receptor mediated permeabilizers are more efficacious than bradykinin in causing the blood-brain barrier to become more ...


3
John W Kozarich, Gary F Musso, Bernard Malfroy Camine: Increasing blood-brain barrier permeability with permeabilizer peptides. Alkermes, Hamilton Brook Smith & Reynolds P C, November 11, 1997: US05686416 (56 worldwide citation)

Peptides called receptor mediated permeabilizers (RMP) increase the permeability of the blood-brain barrier to molecules such as therapeutic agents or diagnostic agents. The permeabilizer A-7 or conformational analogues can be intravenously co-administered to a host together with molecules whose des ...


4
Kozarich John W, Musso Gary F, Malfroy Camine Bernard: Augmentation de la permeabilite de la barriere hemato-encephalique a laide de peptides permeabilisants, Increasing blood-brain barrier permeability with permeabilizer peptides. Alkermes, GOWLING LAFLEUR HENDERSON, October 29, 1992: CA2107556

Peptides called receptor mediated permeabilizers (RMP) increase the permeability of the blood/brain barrier to molecules such as therapeutic agents or diagnostic agents. The permeabilizer A-7 or conformational analogues can be intravenously coad-ministered to a host together with molecules whose des ...


5
Kozarich John W, Musso Gary F, Malfroy Camine Bernard: Increasing blood-brain barrier permeability with permeabilizer peptides. Alkermes, Kozarich John W, Musso Gary F, Malfroy Camine Bernard, BROOK David E, October 29, 1992: WO/1992/018529

Peptides called receptor mediated permeabilizers (RMP) increase the permeability of the blood/brain barrier to molecules such as therapeutic agents or diagnostic agents. The permeabilizer A-7 or conformational analogues can be intravenously coadministered to a host together with molecules whose desi ...


6
Kozarich John W, Musso Gary F, Malfroy Camine Bernard: Increasing blood-brain barrier permeability with permeabilizer peptides.. Alkermes, March 9, 1994: EP0585412-A1

PCT No. PCT/US92/03352 Sec. 371 Date Nov. 12, 1993 Sec. 102(e) Date Nov. 12, 1993 PCT Filed Apr. 23, 1992 PCT Pub. No. WO92/18529 PCT Pub. Date Oct. 29, 1992Peptides called receptor mediated permeabilizers (RMP) increase the permeability of the blood-brain barrier to molecules such as therapeutic ag ...