1
Labadie Sharada Shenvi, Lin Clara Jeou Jen, Talamas Francisco Xavier, Weikert Robert James: Heterocyclic antiviral compounds. F Hoffmann La Roche, Labadie Sharada Shenvi, Lin Clara Jeou Jen, Talamas Francisco Xavier, Weikert Robert James, KJELLSAA BERGER Hanny, August 20, 2009: WO/2009/101022 (21 worldwide citation)

Compounds having the formula (I) wherein Y, R1, R4, A1, A2 and X2 are as defined herein are Hepatitis C virus NS5b polymerase inhibitors. Also disclosed are compositions and methods for treating an HCV infection and inhibiting HCV replication.


2
Billedeau Roland J, Sweeney Zachary Kevin: Heterocyclic antiviral compounds. F Hoffmann La Roche, Billedeau Roland J, Sweeney Zachary Kevin, KJELLSAA BERGER Hanny, July 2, 2009: WO/2009/080534 (12 worldwide citation)

Compounds of formula (I), wherein R1, R2, R3, X1, X2 and Ar, are as defined herein or pharmaceutically acceptable salts thereof, inhibit HIV-I reverse transcriptase and afford a method for prevention and treatment of HIV-I infections and the treatment of AIDS and/or ARC. The present invention also r ...


3
Elbert Chin, Javier de Vicente Fidalgo, Jim Li, Alfred Sui Ting Lui, Kristen Lynn McCaleb, Ryan Craig Schoenfeld, Francisco Xavier Talamas: Heterocyclic antiviral compounds. Roche Palo Alto, Brian L Buckwalter, April 17, 2012: US08158631 (11 worldwide citation)

Compounds having the formula I wherein R1, R2, R3, R4, and R5 are as defined herein are Hepatitis C virus NS5b polymerase inhibitors. Also disclosed are compositions and methods for treating an HCV infection and inhibiting HCV replication.


4
DE VICENTE FIDALGO JAVIER: Heterocyclic antiviral compounds. F HOFFMANN LA ROCHE, Kjellsaa Berger Hanny, March 24, 2011: WO/2011/033045 (8 worldwide citation)

Compounds having the formula I wherein R1, R2, R3, R4, and R5 are as defined herein are Hepatitis C virus NS5b polymerase inhibitors. Also disclosed are compositions and methods for treating an HCV infection and inhibiting HCV replication.


5
LI JIM: Heterocyclic antiviral compounds. F HOFFMANN LA ROCHE, Kjellsaa Berger Hanny, July 1, 2010: WO/2010/072598 (8 worldwide citation)

Compounds having the formula (I) wherein A, R1, R2, R3, R4a, R4b, R4c, R5, R6, R7a, R7b, Ar1, Rc, Rd, Re, Rf, X, n and p are as defined herein are Hepatitis C virus NS5b polymerase inhibitors. Also disclosed are compositions and methods for treating an HCV infection and inhibiting HCV replication.


6
ABBOT Sarah C, LI Jim, LUI Alfred Sui Ting, TALAMAS Francisco Xavier: [fr] COMPOSÉS ANTIVIRAUX HÉTÉROCYCLIQUES, [en] HETEROCYCLIC ANTIVIRAL COMPOUNDS. F HOFFMANN LA ROCHE, ABBOT Sarah C, LI Jim, LUI Alfred Sui Ting, TALAMAS Francisco Xavier, KJELLSAA BERGER Hanny, September 10, 2010: WO/2010/100178 (7 worldwide citation)

[en] Compounds having the formula A-R wherein A is a hetereoaryl and R is Ia, Ib or Ic and wherein A, R, R1, R2a, R2b, R2c, R3a, R3b, R4, R5, R6, Ra, Rb, Rc, Rd, X, X1, X2 and n are as are as defined herein are Hepatitis C virus NS5b polymerase inhibitors. Also disclosed are compositions and methods ...


7
SCHOENFELD RYAN CRAIG: Heterocyclic antiviral compounds. F HOFFMANN LA ROCHE, Kjellsaa Berger Hanny, June 23, 2011: WO/2011/073114 (7 worldwide citation)

Compounds having the formula I wherein R1, R2, R3, R4, R5, Ra, Rb, Rc, Rd and n are as defined herein are Hepatitis C virus NS5b polymerase inhibitors. Also disclosed are compositions and methods for treating an HCV infection and inhibiting HCV replication.


8
James F Blake, Jay Bradford Fell, John P Fischer, Robert Than Hendricks, John E Robinson, Stacey Renee Spencer, Peter J Stengel: Heterocyclic antiviral compounds. Roche Palo Alto, Brian L Buckwalter, January 20, 2009: US07479489 (5 worldwide citation)

Compounds having the formula I wherein A, m and R1 are herein defined are Hepatitis C virus polymerase inhibitors. Also disclosed are compositions and methods for treating diseases mediated by HCV and for inhibiting hepatitis replication. Also disclosed are processes for making the compounds and syn ...


9
Sharada Shenvi Labadie, Clara Jeou Jen Lin, Francisco Xavier Talamas, Robert James Weikert: Heterocyclic antiviral compounds. Roche Palo Alto, Brian L Buckwalter, December 6, 2011: US08071797 (4 worldwide citation)

Compounds having the formula I wherein R1, R2, R3, R4, R5 and X are as defined herein are Hepatitis C virus NS5b polymerase inhibitors. Also disclosed are compositions and methods for treating an HCV infection and inhibiting HCV replication.


10
Brameld Kenneth Albert, Carter David Scott, Chin Elbert, de Vicente Fidalgo Javier, Li Jim, Schoenfeld Ryan Craig, Sjogren Eric Brian, Talamas Francisco Xavier: Heterocyclic antiviral compounds. F Hoffmann La Roche, Brameld Kenneth Albert, Carter David Scott, Chin Elbert, de Vicente Fidalgo Javier, Li Jim, Schoenfeld Ryan Craig, Sjogren Eric Brian, Talamas Francisco Xavier, Kjellsaa Berger Hanny, January 28, 2010: WO/2010/010017 (4 worldwide citation)

Compounds having the formula (I) wherein R1, R2, R3, R4a' R4b' R4c', R5, R6, R9 and n are as defined herein are Hepatitis C virus NS5b polymerase inhibitors. Also disclosed are compositions and methods for treating an HCV infection and inhibiting HCV replication.