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Mark Stearns, Youji Hu: PCAM-1 marker protein, nucleic acid sequences encoding PCAM-1 and immunoassays for detection of PCAM-1. Philadelphia Health and Education Corporation, Morgan Lewis & Bockius, November 6, 2003: US20030207339-A1

The present invention provides a cancer marker protein, PCAM-1, and polynucleotides which identify and encode this protein. Detection of this marker is useful in diagnosing and prognosticating cancer in a patient. Also provided are expression vectors and host cells for expression of PCAM-1 as well a ...


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Mark Stearns, Youji Hu, Min Wang: Prostate cancer-related compositions, methods, and kits based on DNA macroarray proteomics platforms. Philadelphia Health and Education Corporation, Drinker Biddle & Reath, June 30, 2005: US20050142592-A1

The invention relates to novel nucleic acids encoding a mammalian PCADM-1 gene, and proteins encoded thereby, whose expression is increased in certain diseases, disorders, or conditions, including, but not limited to, prostate cancer. The invention further relates to methods of detecting and treatin ...


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Bradford A Jameson, Anna P Tretiakova, Mark K Haynes: Novel spliced 5-HT1A receptors and methods, kits, and uses relating thereto. Philadelphia Health and Education Corporation, Drinker Biddle & Reath, September 15, 2005: US20050202467-A1

The present invention relates to a novel spliced 5-HT1A receptor and nucleic acids encoding the same and the polypeptides encoded thereby.


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Darwin J Prockop, Russell G Reiss, John Langell: Stromal cell use. Philadelphia Health and Education Corporation, Morgan Lewis & Bockius, October 21, 2004: US20040208861-A1

The invention relates to the use of marrow stromal cells to enhance hematopoiesis in a mammal.


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Ira B Black, Dale L Woodbury, Darwin J Prockop, Emily Schwarz: Differentiation of bone marrow cells into neuronal cells and uses therefor. Philadelphia Health And Education Corporation, University Of Medicine And Dentistry Of New Jersey, Seed Intellectual Property Law Group Pllc, June 5, 2008: US20080131407-A1

The present invention relates to methods of inducing differentiation of mammalian bone marrow stromal cells into neuronal cells by contacting marrow stromal cells with a neuronal differentiation-inducing compounds. Neuronal differentiation-inducing compounds of the invention include anti-oxidants su ...


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Peter D Katsikis, Elizabeth S Papazoglou, Margaret A Wheatley, Nadarajan Sundar Babu, Alina Boestcanu: Delivery vehicles, bioactive substances and viral vaccines. Philadelphia Health and Education Corporation, Drinker Biddle & Reath, August 10, 2006: US20060177468-A1

The invention relates to compositions and methods for the safe delivery of a bioactive agent to an animal. Preferably, the bioactive agent is a vaccine, and more preferably, the bioactive agent is a virus.


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Mark Stearns, Youji Hu, Min Wang: Prostate Cancer-Related Compositions, Methods and Kits Based on DNA Macroarray Proteomics Platforms. Philadelphia Health And Education Corporation, D B A Drexel University College Of Medicine, Drinker Biddle & Reath, September 2, 2010: US20100221753-A1

The invention relates to novel nucleic acids encoding a mammalian PCADM-1 gene, and proteins encoded thereby, whose expression is increased in certain diseases, disorders, or conditions, including, but not limited to, prostate cancer. The invention further relates to methods of detecting and treatin ...


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Darwin J Prockop, David G Stokes, S Ausim Azizi: Isolated stromal cells for use in the treatment of diseases of the central nervous system. Philadelphia Health And Education Corporation, Seed Intellectual Property Law Group Pllc, August 27, 2009: US20090214492-A1

Methods of treating a human patient having a disease, disorder or condition of the central nervous system are disclosed. The methods include obtaining a bone marrow sample from a human donor, isolating stromal cells from the bone marrow sample, and administering the isolated stromal cells to the cen ...


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Peter D Katsikis, Alina C Boesteanu, Martin Turner: Role of PI3K p110 delta Signaling in Retroviral Infection and Replication. PHILADELPHIA HEALTH AND EDUCATION CORPORATION d b a Drexel University College of Medicine, The Babraham Institute, June 9, 2011: US20110135655-A1

The invention includes compositions and methods for regulating PI3K p110 delta as an anti-retroviral therapy. The invention includes inhibiting p110 delta, a component of PI3K p110 delta signaling pathway, or any combination thereof in a cell as an anti-retroviral therapeutic approach for treating a ...