11
Randolph S Porubcan, Jeff Thurston: On-line authentication of probiotics to ensure source and quality. Master Supplements, Eric P Mirabel, September 16, 2014: US08833643 (2 worldwide citation)

Disclosed is encoding of probiotic formulations, in order to alert both consumer and producer to counterfeiting and to allow purchasers of authentic product to gain access to quality and quantity testing regarding the product. The purchaser would preferably also provide, along with its identifying i ...


12
Gopi Hosahudya, Irwin Chaiken: Dual inhibitors of HIV-1 gp-120 interactions. Philadelphia Health and Education Corporation, Drinker Biddle & Reath, July 7, 2009: US07556808 (2 worldwide citation)

Compounds, which inhibit the binding of gp120 to CD4 as well as 17b and methods for their use in inhibiting the HIV fusion process, are provided.


13
Reiner J W Class, Christopher M Hand: Antimicrobial histone H1 compositions, kits, and methods of use thereof. Philadelphia Health and Education Corporation, Licata & Tyrrell P C, May 20, 2003: US06565854 (1 worldwide citation)

The invention includes antibiotic pharmaceutical compositions comprising eukaryotic histone H1 protein and methods of using eukaryotic histone H1 protein to kill or to inhibit the growth of microorganisms, including, but not limited to, human pathogenic bacteria. The invention further includes a euk ...


14
Hosahudya Gopi, Irwin Chaiken: Dual inhibitors of HIV-1 gp-120 interactions. Philadelphia Health and Education Corporation, Riverside Law, January 10, 2012: US08092805 (1 worldwide citation)

Compounds, which inhibit the binding of gp120 to CD4 as well as 17b and methods for their use in inhibiting the HIV fusion process, are provided.


15
LUTZ GORDON J: Modulation of pre-mrna using splice modulating oligonucleotides as therapeutic agents in the treatment of disease. PHILADELPHIA HEALTH AND EDUCATION CORPORATION, Haas Dennis L, July 22, 2010: WO/2010/083338 (1 worldwide citation)

The present invention encompasses a class of compounds known as splice modulating oligonucleotides (SMOs) that modulate pre-mRNA splicing, thereby affecting expression and functionality of a specific protein in a cell. The present invention further provides compositions and methods for modulating pr ...


16
Sharma Mahesh C, Tuszynski George P: Methods and compositions for inhibiting angiogenesis. Philadelphia Health And Education Corporation, Sharma Mahesh C, Tuszynski George P, LICATA Jane Massey, March 7, 2002: WO/2002/017857 (1 worldwide citation)

Methods for inhibiting angiogenesis in endothelial cells and selectively inducing apoptosis in endothelial cells via compounds which binds annexin II are provided. These compounds and methods for using these compounds are useful in the treatment of diseases or disorders characterized by unwanted ang ...


17
Nick Loizos, Alessandro Fatatis, Nathan Graeme Dolloff: Methods of treating secondary bone tumors with antibodies against PDGFR alpha. ImClone, Philadelphia Health and Education Corporation, Nicole S Woods, April 23, 2013: US08425911

The invention provides methods of treating bone cancer, particularly metastatic bone cancer, by administering a PDGFR alpha antagonist. The invention further provides methods of treating a mammal with a neoplastic disease using the antibodies alone or in combination with other agents.


18
Dennis L Gierhart: Zeaxanthin formulations with additional ocular-active nutrients, for protecting eye health and treating eye disorders. ZeaVision, Nixon Peabody, May 29, 2018: US09980922

Oral formulations for promoting eye health, and in particular for preventing or treating macular degeneration, are disclosed, containing zeaxanthin, a carotenoid pigment, and at least two or more additional ocular-active nutrients selected from lipoic acid, omega-3 fatty acids, plant-derived compoun ...


19
Elizabeth McKenna: Naturally-occurring CpG oligonucleotide compositions and therapeutic applications thereof. LABYRINTH HOLDINGS, McDonnell Boehnen Hulbert & Berghoff, April 3, 2018: US09931398

The present invention relates to combination therapies for the treatment of a variety of disorders in mammals, including hepatic disorders and cancer. The combination of agents includes naturally-occurring (versus synthetic) oligonucleotides, particularly immunostimulatory oligodeoxynucleotides such ...


20
Bradford A Jameson, Anna A Tretiakova, Ross Albert, Harold Carter Davidson: Immunomodulation and effect on cell processes relating to serotonin family receptors. Philadelphia Health and Education Corporation, Drinker Riddle & Reath, December 27, 2005: US06979447

The present invention relates to the discovery that signaling via a serotonin type 1B, 2, 4 and 6 receptor is important in T cell activation such that inhibiting such signaling can be used to modulate the immune response. This immunomodulation is useful for the treatment of immune diseases or condit ...