Timothy J Cunningham, Forrest Haun, Kathie L Eagleson, Pat R Levitt, Sarah E Kennedy: Neuron regulatory factor for promoting neuron survival. Philadelphia Health and Education Corporation, Dann Dorfman Herrell and Skillman, July 17, 2001: US06262024 (10 worldwide citation)

A neuron regulatory factor (NRF), derived from cells of the central nervous system, is provided. A cytoprotective peptide (CPP) component of NRF is also provided, as are methods of using NRF or its CPP component. NRF comprises a large polypeptide or complex of polypeptides that is distinct from seve ...

KATSIKIS PETER D: The role of p110 delta signaling in morbidity and lung pathology induced by influenza virus infection. PHILADELPHIA HEALTH AND EDUCATION CORPORATION, Nguyen Quang D, July 22, 2010: WO/2010/083163 (5 worldwide citation)

The invention includes compositions and methods for regulating p110 delta as an anti-influenza virus therapy. The invention includes inhibiting p110 delta, a component of p110 delta signaling pathway, or any combination thereof in a cell as an anti-influenza viral therapeutic approach for treating i ...

Ira B Black, Dale L Woodbury, Darwin J Prockop, Emily Schwarz: Differentiation of bone marrow cells into neuronal cells and uses therefor. Philadelphia Health and Education Corporation, University of Medicine and Dentistry of New Jersey, Seed IP Law Group PLLC, October 9, 2007: US07279331 (4 worldwide citation)

The present invention relates to methods of inducing differentiation of mammalian bone marrow stromal cells into neuronal cells by contacting marrow stromal cells with a neuronal differentiation-inducing compounds. Neuronal differentiation-inducing compounds of the invention include anti-oxidants su ...

Reiner Class, Michael Zeppezauer: Antimicrobial histone H1 compositions, kits, and methods of use thereof. Symbiotec, Philadelphia Health and Education Corporation, Akin Gump Strauss Hauer & Feld, April 26, 2005: US06884423 (3 worldwide citation)

The invention includes antibiotic pharmaceutical compositions comprising eukaryotic histone H1 protein and methods of using eukaryotic histone H1 protein to kill or to inhibit the growth of microorganisms, including, but not limited to, human pathogenic bacteria. The invention further includes a euk ...

Taffy Williams, George Tuszynski, Paul Actor: Compositions for treating chemotherapy-resistant tumor cells and targeted chemotherapy compositions. Inkine Pharmaceutical Company, Philadelphia Health and Education Corporation, Finnegan Henderson Farabow Garrett & Dunner L, April 30, 2002: US06380161 (3 worldwide citation)

The present invention provides methods and compositions for treating cancer and chemotherapy-resistant cancers comprising a chemotherapeutic agent conjugated to or coadministered with a peptide.

Darwin J Prockop, David Colter, Carla DiGirolamo: Isolation and expansion of human marrow stromal cells. Philadelphia Health and Education Corporation, Seed IP Law Group PLLC, May 20, 2008: US07374937 (3 worldwide citation)

The invention includes in vitro methods of inducing and enhancing proliferation of human marrow stromal cells for use in, for example, gene therapy and transplantation methods. The invention also includes a method of assessing the expandability (i.e., proliferative capacity) of human marrow stromal ...


Tawanna Alyce Marshall: Method and materials for teaching the phonetic code and repairing self esteem. November 27, 2001: US06322367 (2 worldwide citation)

This invention of materials and method is designed for assessment of phonetic reading ability and for teaching the phonetic reading code to children and adults of average intelligence and abilities who have responded poorly to traditional reading instructional methods or who choose not to be limited ...

Mark Stearns, Youji Hu, Min Wang: Prostate cancer-related compositions, methods, and kits based on DNA macroarray proteomics platforms. Philadelphia Health and Education Corporation, Drinker Biddle & Reath, July 13, 2010: US07754435 (2 worldwide citation)

The invention relates to novel nucleic acids encoding a mammalian PCADM-1 gene, and proteins encoded thereby, whose expression is increased in certain diseases, disorders, or conditions, including, but not limited to, prostate cancer. The invention further relates to methods of detecting and treatin ...

Mark Thomas Boyd, Dale Stewart Haines, Nikolina Vlatkovic: Mammalian MDM2 binding proteins and uses thereof. Philadelphia Health and Education Corporation, Licata & Tyrrell P C, January 23, 2007: US07166712 (2 worldwide citation)

Isolated nucleic acid sequences encoding mammalian MDM2 binding protein and polypeptide sequences for the mammalian MDM2 binding protein are provided. Also provided are vectors containing these nucleic acid sequences, host cells which express these proteins and antibodies targeted to these proteins. ...