1
Robert Vincent Fishleigh, Barry Robson, Roger Paul Mee: Fragments of prion proteins. Proteus Molecular Design, Pennie & Edmonds, June 30, 1998: US05773572 (20 worldwide citation)

Synthetic polypeptides having at least one antigenic site of a prion protein are disclosed together methods for their use and manufacture and antibodies raised against such polypeptides. Diagnostic kits using the polypeptides and/or antibodies are also disclosed.


2
Bruce W Chesebro, Byron W Caughey, Joelle Chabry, Suzette Priola: Inhibitors of formation of protease resistant prion protein. The United States of America represented by the Department of Health & Human Services, Klarquist Sparkman, March 12, 2002: US06355610 (7 worldwide citation)

Peptides are disclosed that inhibit the conversion of protease sensitive prion protein (PrPsen) to the protease resistant isoform (PrPres). These peptides comprise discrete fragments of prion proteins, and are shown to inhibit the in vitro conversion of PrPsen to PrPres in a cell-free system. Numero ...


3
Robert Vincent Fishleigh, Barry Robson, Roger Paul Mee: Fragments of prion proteins. Proteus Molecular Design, Pennie & Edmonds, April 30, 2002: US06379905 (6 worldwide citation)

Synthetic polypeptides having at least one antigenic site of a prion protein, methods for their use and manufacture, antibodies raised against such polypeptides and diagnostic kits containing these polypeptides or antibodies.


4
Bruce W Chesebro, Byron W Caughey, Joelle Chabry, Suzette Priola: Inhibitors of formation of protease resistant prion protein. The United States of America represented by the Department of Health and Human Services, Klarquist Sparkman Campbell & Leigh & Whinston, April 3, 2001: US06211149 (4 worldwide citation)

Peptides are disclosed that inhibit the conversion of protease sensitive prion protein (PrPsen) to the protease resistant isoform (PrPres). These peptides comprise discrete fragments of prion proteins, and are shown to inhibit the in vitro conversion of PrPsen to PrPres in a cell-free system. Numero ...


5
Bruce W Chesebro, Byron W Caughey, Joelle Chabry, Suzette Priola: Inhibitors of formation of protease resistant prion protein. Government of the US of America Secretary of the Department of Health and Human Services, Klarquist Sparkman Campbell, Leigh & Whinston, November 15, 2001: US20010041790-A1

Peptides are disclosed that inhibit the conversion of protease sensitive prion protein (PrPsen) to the protease resistant isoform (PrPres). These peptides comprise discrete fragments of prion proteins, and are shown to inhibit the in vitro conversion of PrPsen to PrPres in a cell-free system. Numero ...


6
Robert Vincent Fishleigh, Barry Robson, Roger Paul Mee: Fragments of prion proteins. Proteus Molecular Design, Pennie & Edmonds, October 23, 2003: US20030199013-A1

Synthetic polypeptides having at least one antigenic site of a prior protein, methods for their use and manufacture, antibodies raised against such polypeptides and diagnostic kits containing these polypeptides or antibodies.


7
Fishleigh Robert Vincent, Robson Barry, Mee Roger Paul: Fragments of prion proteins. Proteus Molecular Design, Fishleigh Robert Vincent, Robson Barry, Mee Roger Paul, FRANK B DEHN Imperial House 15 19 Kingsway London WC2B 6UZ, June 10, 1993: WO/1993/011155

Synthetic polypeptides having at least one antigenic site of a prion protein are disclosed together with methods for their use and manufacture and antibodies raised against such polypeptides. Diagnostic kits using the polypeptides and/or antibodies are also disclosed.


8
Fishleigh Robert Vincent Bradl, Robson Barry The Old Bakery A, Mee Roger Paul: Fragments of prion proteins.. Proteus Molecular Design, September 28, 1994: EP0616613-A1

Synthetic polypeptides having at least one antigenic site of a prion protein are disclosed together with methods for their use and manufacture and antibodies raised against such polypeptides. Diagnostic kits using the polypeptides and/or antibodies are also disclosed.