1
Salvador M Fernandez, Ernest St Louis, Ralph Levy, Ernest F Gulgon, Sean Cobane: Apparatus and method for phase fluorometry. Ciencia, Alix Yale & Ristas, October 6, 1998: US05818582 (111 worldwide citation)

A phase fluorometer employs a baseband frequency generator to generate a sample baseband signal at a first frequency f.sub.o and a reference signal correlated to the sample baseband signal. A second signal generator generates a carrier signal having a second frequency f. The sample baseband signal a ...


2
Walter B Dandliker, Howard S Barr, Henry S Katzenstein, Keith R Watson: Fluorometer. Diatron Corporation, Ellsworth R Roston, Charles H Schwartz, October 31, 1989: US04877965 (93 worldwide citation)

A fluorometer for measuring a particular fluorescence emanating from a specimen and operating in accordance with the following method. Producing a burst of concentrated light energy and directing the concentrated light energy toward the specimen to produce a fluorescence from the specimen including ...


3
Kenneth F Buechler, Joseph M Anderberg, Paul H McPherson: Media carrier for an assay device. Biosite Diagnostics, Richard Warburg, June 13, 2000: US06074616 (79 worldwide citation)

A fluorometer for sensing the fluorescence of a sample utilizes an optical energy source for exciting a sample to be tested and an optical energy detector for detecting the emitted energy from the excited sample. Drive electronics are used for positioning the sample with respect to the optical compo ...


4
Gunner Bolz, Fred H Deindoerfer, Chun P Hu, Naomi Kameda, Robert Wang: Method for quantitation of antigens or antibodies on a solid surface. International Diagnostic Technology, Flehr Hohbach Test Albritton & Herbert, April 26, 1977: US04020151 (72 worldwide citation)

A method for quantitation of antigens or antibodies from a liquid sample on a solid surface. The sample is first sorbed directly to a nonimmunological surface. Then the surface is exposed to antibody or antigen labelled preferably with a fluorogen, to cause an immunological reaction to occur. After ...


5
Brett A Feddersen, Enrico Gratton, David W Piston: Method and means for parallel frequency acquisition in frequency domain fluorometry. Research Corporation Technologies, Scully Scott Murphy & Presser, October 26, 1993: US05257202 (72 worldwide citation)

A digital frequency domain fluorometer utilizing a computer-controlled digital data acquisition system is use for the study of fluorescence and phosphorescence phenomena in the bio-chemical, biological and bio-physics arts. The computer is used for the direct collection of data, as well as for the f ...


6
G Terrance Walker, James G Nadeau, C Preston Linn: Fluorerscence polarization detection of nucleic acid amplication. Becton Dickinson and Company, Donna R Fugit, January 14, 1997: US05593867 (68 worldwide citation)

Fluorescence polarization methods for detection of nucleic acid amplification. A fluorescently labelled oligodeoxynucleotide probe is converted from single- to double-stranded form in a target dependent manner during amplification of the target sequence. This conformational change is accompanied by ...


7
Nils R D Aslund, Kjell S Carlsson: Apparatus for quantitative imaging of multiple fluorophores. Schneck & McHugh, March 15, 1994: US05294799 (65 worldwide citation)

A quantitative fluorometer for multiple fluorophores having a separate time-modulated beam of excitation light for each fluorescent target. Each beam is synchronized with a separate lock-in amplifier. The fluorophores are simultaneously excited and the combined fluorescent emission is resolved into ...


8
Cass J Grandone: Locking rack and disposable sample cartridge. Abbott Laboratories, Richard D Schmidt, John W Cornell, Donald L Corneglio, September 11, 1990: US04956148 (63 worldwide citation)

A plurality of disposable cartridges, each having a plurality of wells including at least one assay reaction well, are loaded in a plurality of openings arranged radially around a rack of a carousel. Securing of the cartridges in a predetermined orientation and position in said openings is ensured b ...


9
Robert Giebeler, David G Ogle, Roger Kaye, Dean Hafeman: Optical system for a scanning fluorometer. Molecular Devices Corporation, David G Beck, McCutchen Doyle Brown & Enersen, May 22, 2001: US06236456 (63 worldwide citation)

A method and apparatus for determining the fluorescence, luminescence, or absorption of a sample is provided. The sample may either be contained within a cuvette or within one or more sample wells within a multi-assay plate. A combination of a broadband source, a monochromator, and a series of optic ...


10
Chance Britton: Time-sharing fluorometer and reflectometer. Gordon Herman L, May 21, 1974: US3811777 (61 worldwide citation)

A spectrophotometric probe apparatus including a light source, a photomultiplier and a rotary filter wheel, with respective light pipes located to receive excitation light through one filter from the source and to transmit emission or reflectance light through an opposite filter to the photomultipli ...