51
Rathin Datta: Process for the production of succinic acid by anaerobic fermentation. Quarles & Brady, September 1, 1992: US05143833 (79 worldwide citation)

A method of producing succinic acid comprises growing a succinate producing microorganism in medium containing sodium ions an assimilable carbohydrate, other required nutrients and dissolved carbon dioxide at pH of about 5.8 to about 6.4. The succinic acid can be isolated from the fermentation broth ...


52
Thomas M Brennan: Determining DNA sequences by mass spectrometry. Genomyx, Allegretti & Witcoff, March 26, 1991: US05003059 (78 worldwide citation)

This invention relates to the methods, apparatus, reagents and mixtures of reagents for sequencing natural or recombinant DNA and other polynucleotides. In particular, this invention relates to a method for sequencing polynucleotides based on mass spectrometry to determine which of the four bases (a ...


53
Kenneth S Kang, George T Veeder: Polysaccharide S-60 and bacterial fermentation process for its preparation. Merck & Co, Gabriel Lopez, Hesna J Pfeiffer, April 20, 1982: US04326053 (78 worldwide citation)

A novel polysaccharide S-60 is disclosed composed of principally carbohydrate, 10-15% protein, and 3-4.5% acetyl groups as the O-glycosidically linked ester. The carbohydrate portion contains about 11% glucuronic acid (based on wt. gum) and the neutral sugars rhamnose and glucose, the latter having ...


54
Wood Irwin Bovden, Pankavich John Anthony, Carter Guy Thomas, Torrey Margaret Jennings, Greenstein Michael: Method and compositions for helmintic, arthropod ectoparasitic and acaridal infections with novel agents.. American Cyanamid Co, February 5, 1986: EP0170006-A2 (78 worldwide citation)

The present invention relates to novel agents, to their production by fermentation, to methods for their recovery and concentration from crude solutions, to processes for their purification and to pharmaceutically and pharmacologically-acceptable salts thereof. Also, this invention relates to method ...


55
Beppu Teruhiko, Uozumi Takeshi, Nishimori Katsuhiko, Shimizu Norio, Kawaguchi Yoshiyuki, Hidaka Makoto: Novel expression plasmids and their use in the method for expressing prochymosin coding gene in e. coli.. Beppu Teruhiko, October 17, 1984: EP0121775-A1 (78 worldwide citation)

Improved methods are provided for replication and expression of prochymosin coding gene in E. coli. Novel expression plasmids having prochymosin coding gene operatively attached to the E. coli trp operon have been developed. These plasmids have been inserted into E. coli host cells by transformation ...


56
David E Hallberg: Integrated process for producing ethanol, methanol and butyl ethers. Revolution Fuels of America, December 3, 1991: US05070016 (77 worldwide citation)

A methanol synthesis and an ethanol synthesis are integrated into a single continuous process with the by-product carbon dioxide generated in the ethanol synthesis being utilized in the methanol synthesis. The methanol synthesis and ethanol synthesis can be further integrated with isobutylene synthe ...


57
David Edward Ramey: Continuous two stage, dual path anaerobic fermentation of butanol and other organic solvents using two different strains of bacteria. Environmental Energy, Frank H Kremblas Foster Millard & Pollick Foster, May 19, 1998: US05753474 (77 worldwide citation)

The instant invention describes a process for the manufacture of butanol and like volatile organic compounds by fermenting carbohydrates, mainly polysaccharide, with micro-organisms which convert carbohydrates into mainly butyric acid and other acids. The acids are subsequently transferred to the so ...


58
Thomas M Brennan: Apparatus for determining DNA sequences by mass spectrometry. Genomyx, Allegretti & Witcoff, December 29, 1992: US05174962 (77 worldwide citation)

This invention relates to the apparatus, for sequencing natural or recombinant DNA and other polynucleotides. In particular, this invention relates to a method for sequencing polynucleotides based on mass spectrometry to determine which of the four bases (adenine, guanine, cytosine or thymine) is a ...


59
Ho Lun Lee: Concentrated xanthan gum solutions. Celanese Corporation, November 10, 1981: US04299825 (77 worldwide citation)

This invention provides a process for clarifying and concentrating Xanthomonas heteropolysaccharide fermentation broth, which process includes filtration and ultrafiltration steps.


60
Rathin Datta, David A Glassner, Mahendra K Jain, John R Vick Roy: Fermentation and purification process for succinic acid. Quarles & Brady, December 1, 1992: US05168055 (76 worldwide citation)

A process for economically producing highly purified succinic acid comprises growing a succinate-producing microorganism on a low cost carbohydrate substrate; simultaneously neutralizing the fermentation broth and precipitating the succinate as calcium succinate by adding a calcium ion source to for ...



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