61
John William d Eveleigh, Robert K Kobos: Enzyme immobilization and bioaffinity separations with perfluorocarbon polymer-based supports. E I Du Pont De Nemours and Company, George A Frank, December 5, 1989: US04885250 (25 worldwide citation)

A bioaffinity separation method is provided along with a solid affinity support utilized in that method. Additionally, immobilized enzyme systems are provided for use as enzyme electrode systems. The support is based on an inert perfluorocarbon polymer carrier with ligands or binders attached to its ...


62
David Avnir, Michael Ottolenghi, Sergei Braun, Rivka Zusman: Doped sol-gel glasses for obtaining chemical interactions. YISSUM Research Development Company of the Hebrew University of Jerusalem, Lowe Price LeBlanc & Becker, April 5, 1994: US05300564 (25 worldwide citation)

A method is proposed of obtaining a chemical interaction between at least one reagent trapped in sol-gel glass by doping it with the reagent, and diffusible solutes or components in an adjacent liquid or gas phase. The reagents, the solutes or the components can be any organic or inorganic compounds ...


63
Tatsuhiko Osaka, Hiroshi Terawaki, Mitsunari Okamoto: Diffusion-limiting membrane holding means for sensor. Daikin, Beveridge DeGrandi & Weilacher, May 29, 1990: US04929330 (21 worldwide citation)

A diffusion-limiting membrane holding means for a sensor comprising: a slender resilient thin plate, of which one shorter side serves as an engagement side, and of which one longer side is provided at its predetermined position with an engagement portion, an opening being formed in the thin plate be ...


64
Eveleigh John William Delouche, Kobos Robert Kenneth: Enzyme immobilization and bioaffinity separations with perfluorocarbon polymer-based supports.. Du Pont, September 7, 1988: EP0281368-A2 (21 worldwide citation)

A bioaffinity separation method is provided along with a solid affinity support utilized in that method. Additionally, immobilized enzyme systems are provided for use as enzyme electrode systems. The support is based on an inert carrier with ligands or binders attached to its surface. Methods for pr ...


65
J Stuart Parsons, Jon Booher: Method for monitoring glucose level. Health Craft International, Christie Parker & Hale, October 15, 1991: US05056521 (20 worldwide citation)

A sample of oral fluid is collected by an absorbent nonreactive collecting swab brought into contact with a favorable surface in the oral cavity. The fluid is interstitial transudate selectively collected from the vestibule region of the oral cavity at the junction of the superior labial mucous memb ...


66
Deng Yingping, Chu Amy H: Method of detecting bias in enzyme electrode measurements. Bayer Healthcare, August 18, 2004: EP1447452-A1 (20 worldwide citation)

A method of determining the concentration of an analyte in a fluid test sample that includes providing an electrochemical sensor adapted to measure the analyte in the test sample. The test sample sufficiently covers a counter and working electrode of the electrochemical sensor. A first potential is ...


67
David Avnir, Michael Ottolenghi, Sergei Braun, Rivka Zusman: Doped sol-gel glasses for obtaining chemical interactions. Yissum Research Development Company of the Hebrew University of Jerusalem Israel, Lowe Price LeBlanc & Becker, July 22, 1997: US05650311 (18 worldwide citation)

A metod is proposed of obtaining a chemical interaction between at least one reagent trapped in sol-gel glass by doping it with the reagent(s), and diffusible solutes or components in an adjacent liquid or gas phase. The reagents, the solutes or the components can be any organic or inorganic compoun ...


68
Philippe Racine, Jean Claude Higelin, Roland Engelhardt, Wolfgang Mindt: Method for measuring substrate concentrations. Hoffmann La Roche, Jon S Saxe, George M Gould, December 12, 1978: US04129478 (17 worldwide citation)

The concentration of substrates of enzyme reactions is measured by determining the current produced at an platinum or gold electrode by oxidizing an acceptor utilizing a measuring device comprising a measuring cell, an enzyme electrode in contact with the fluid sample and containing an platinum or g ...


69
Pankaj Madganlal Vadgama, Paul William Crump: Monitoring systems. The Victoria University of Manchester, Pillsbury Madison & Sutro, May 16, 2000: US06064900 (15 worldwide citation)

Method and electrode assemblies for using or installing an electrode (especially enzyme electrode) in vivo, in which a protecting medium is introduced at the installation site to suppress adverse effects on the electrode's output. The medium is preferably an isotonic solution (e.g. saline) and/or a ...


70
Atsushi Saito: Enzyme electrode and a method of determining concentration of an analyte in a sample solution. NEC Corporation, Laff Whitesel Conte & Saret, June 2, 1992: US05118404 (15 worldwide citation)

An enzyme electrode usable for determining high concentration of analyte in a sample solution is provided, by providing an enzyme-immobilized membrane in the electrode with pH buffer capacity. Durability of the electrode can be improved by using albumin crosslinked by glutaraldehyde as a permeation- ...