21
Kenichi Nakamura, Shiro Nankai, Takashi Iijima: Electrochemical measuring apparatus comprising enzyme electrode. Matsushita Electric Industrial, Wenderoth Lind & Ponack, July 12, 1983: US04392933 (312 worldwide citation)

An immobilized enzyme electrode effective in measurement of the substrate concentration of the enzyme and in conversion from enzyme reaction energies into electric energies. The immobilized enzyme, of an oxidase system, such as glucose oxidase, amino acid oxidase, xanthine oxidase or the like and a ...


22
Pepi Ross, Marc J Madou, Zoila Reyes, Joel F Jensen, Sharon W Wing, Virginia G Rimer: Electrochemical cncentration detector method. Neuman Williams Anderson & Olson, March 20, 1990: US04909908 (311 worldwide citation)

Electrochemical biosensor systems or apparatus, components thereof, and methods for quantitatively measuring or assaying concentrations of selective substrates or metabolites in aqueous media as a function of electrochemical response to hydrogen peroxide concentration, using immobilized enzyme elect ...


23
Shuichi Suzuki, Masuo Aizawa, Masao Koyama, Yuichi Sato, Junji Koezuka: Electrochemical measuring apparatus provided with an enzyme electrode. Tokyo Shibaura Denki Kabushiki Kaisha, Oblon Fisher Spivak McClelland & Maier, June 14, 1983: US04388166 (301 worldwide citation)

An electrochemical measuring apparatus which essemtially comprises an asymmetric semipermeable membrane mounted on an immobilized enzyme membrane of an enzyme electrode, said asymmetric semipermeable membrane being essentially formed of a thin semipermeable layer exposed to the outside for contact w ...


24
Richard Riffer: Enzyme electrode and method for dextran analysis. California and Hawaiian Sugar Company, Robert G Slick, November 12, 1985: US04552840 (300 worldwide citation)

A method for the potentiometric determination of a dextran solution is provided wherein the dextran is enzymatically hydrolyzed to glucose, the glucose is oxidized to form hydrogen peroxide and the hydrogen peroxide is measured utilizing a redox electrode. A novel electrode having a plurality of enz ...


25
Paul A D Orazio, Arthur R Eddy Jr, Eric J Fogt, James E Jones, Bruce J Oberhardt: Enzyme electrode membrane. Miles Laboratories, Roger N Coe, November 15, 1983: US04415666 (300 worldwide citation)

A membrane for electrochemical analysis is described comprising a first, relatively dense and thin layer and a second, relatively porous thick layer, which thick layer has dispersed therethrough the enzyme, glucose oxidase. The process of making the membrane by casting two to three layers of cellulo ...


26
Mariko Kawaguri, Shiro Nankai, Takashi Iijima: Solid state bio-sensor. Matsushita Electric Industrial, Birch Stewart Kolasch & Birch, December 15, 1992: US05171689 (294 worldwide citation)

As the conventional simple bio-sensors for measuring the particular component in living bodies, there are those in which a change in dye caused by enzyme reaction is detected optically, but such bio-sensors had a problem that precision is low owing to disturbance of the color of liquid samples. With ...


27
Koichi Takizawa, Satoshi Nakajima, Masato Arai: Enzyme electrode. Omron Tateisi Electronics Co, Wegner & Bretschneider, January 16, 1990: US04894137 (293 worldwide citation)

An enzyme electrode comprising: an insulative base plate; two or more electrodes formed on the surface of the insulative base plate and each having an exposed portion; an insulative protection film to insulate and protect the electrodes excluding at least those exposed portions; and an immobilized e ...


28
David P Newman: Membrane for enzyme electrodes. The Yellow Springs Instrument Company, Biebel French & Nauman, February 14, 1978: US04073713 (272 worldwide citation)

A laminated membrane for use with an enzyme electrode without the need for use of a compensating electrode. The laminated membrane comprises a layer of essentially homogeneous material such as cellulose acetate or silicone rubber which will prevent passage of even low molecular weight interfering ma ...


29
Pankaj M Vadgama, William H Mullen, Graham W Scott: Enzyme electrode and membrane. Imperial Chemical, Cushman Darby & Cushman, May 23, 1989: US04832797 (263 worldwide citation)

A membrane particularly for use in a sensor of the enzyme-electrode type which comprises one or more layers of material and an enzyme-containing layer and in which one layer is formed from a sulphonated or unsulphonated polyarylsulphone or a sulphonated or unsulphonated polyarylketone. The specifica ...


30
Karube Isao, Clark Susan Anne, Nagata Ryohei: Enzyme-immobilized electrode, composition for preparation of the same and electrically conductive enzyme.. Dainippon Printing, Karube Isao, October 6, 1993: EP0563795-A1 (259 worldwide citation)

An enzyme sensor system capable of quantitatively determining a particular component contained in a biological sample in a rapid and easy manner is disclosed. More particularly, an electrically conductive enzyme, an enzyme-immobilized electrode using the same and a composition for use in the prepara ...