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Davis S Christopher, Grate John H, Gray David R, Gruber John M, Huisman Gjalt W, Ma Steven K, Newman Lisa M, Sheldon Roger, Wang Li A: Enzymatic processes for the production of 4-substituted 3-hydroxybutyric acid derivatives and vicinal cyano, hydroxy substituted carboxylic acid esters. Codexis, Davis S Christopher, Grate John H, Gray David R, Gruber John M, Huisman Gjalt W, Ma Steven K, Newman Lisa M, Sheldon Roger, Wang Li A, FUJITA Sharon M, March 3, 2005: WO/2005/018579 (42 worldwide citation)

The present invention provides methods and composition for preparing 4-substituted 3-hydroxybutyric acid derivatives by halohydrin dehalogenase-catalyzed conversion of 4-halo-3-hydroxybutyric acid derivatives. The present invention further provides methods and compositions for preparing 4-halo-3-hyd ...


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S Christopher Davis, John H Grate, David R Gray, John M Gruber, Gjalt W Huisman, Steven K Ma, Lisa M Newman, Roger Sheldon, Li A Wang: Enzymatic processes for the production of 4-substituted 3-hydroxybutyric acid derivatives. Codexis, Dechert, October 24, 2006: US07125693 (36 worldwide citation)

The present invention provides methods and compositions for preparing 4-substituted 3-hydroxybutyric acid derivatives by halohydrin dehalogenase-catalyzed conversion of 4-halo-3-hydroxybutyric acid derivatives. The present invention further provides methods and compositions for preparing 4-halo-3-hy ...


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S Christopher Davis, John H Grate, David R Gray, John M Gruber, Gjalt W Huisman, Steven K Ma, Lisa M Newman, Roger Sheldon, Li A Wang: Enzymatic processes for the production of 4-substituted 3-hydroxybutyric acid derivatives and vicinal cyano, hydroxy substituted carboxylic acid esters. Codexis, Delchert, November 7, 2006: US07132267 (35 worldwide citation)

The present invention provides methods and compositions for preparing 4-substituted 3-hydroxybutyric acid derivatives by halohydrin dehalogenase-catalyzed conversion of 4-halo-3-hydroxybutyric acid derivatives. The present invention further provides methods and compositions for preparing 4-halo-3-hy ...


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Davis S Christopher, Grate John H, Gray David R, Gruber John M, Huisman Gjalt W, Ma Steven K, Newman Lisa M, Sheldon Roger, Wang Li A: Enzymatic processes for the production of 4-substituted 3-hydroxybutyric acid derivatives. Codexis, Davis S Christopher, Grate John H, Gray David R, Gruber John M, Huisman Gjalt W, Ma Steven K, Newman Lisa M, Sheldon Roger, Wang Li A, KRUSE Norman J, February 19, 2004: WO/2004/015132 (13 worldwide citation)

The present invention provides methods and compositions for preparing 4-substituted 3-hydroxybutyric acid derivatives by halohydrin dehalogenase-catalyzed conversion of 4-halo-3-hydroxybutyric acid derivatives. The present invention further provides methods and compositions for preparing 4-halo-3-hy ...


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S Christopher Davis, John H Grate, David R Gray, John M Gruber, Gjalt W Huisman, Steven K Ma, Lisa M Newman, Roger Sheldon, Li A Wang: Enzymatic processes for the production of 4-substituted 3-hydroxybutyric acid derivatives. Codexis, Dechert, October 5, 2010: US07807423

The present invention provides methods and compositions for preparing 4-substituted 3-hydroxybutyric acid derivatives by halohydrin dehalogenase-catalyzed conversion of 4-halo-3-hydroxybutyric acid derivatives. The present invention further provides methods and compositions for preparing 4-halo-3-hy ...


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Davis S Christopher, Grate John H, Gray David R, Gruber John M, Huisman Gjalt W, Ma Steven K, Newman Lisa M, Sheldon Roger, Wang Li A: Enzymatic processes for the production of 4-substituted 3-hydroxybutyric acid derivatives. Codexis, June 8, 2005: EP1537222-A2

The present invention provides methods and compositions for preparing 4-substituted 3-hydroxybutyric acid derivatives by halohydrin dehalogenase-catalyzed conversion of 4-halo-3-hydroxybutyric acid derivatives. The present invention further provides methods and compositions for preparing 4-halo-3-hy ...


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Davis S Christopher, Grate John H, Gray David R, Gruber John M, Huisman Gjalt W, Ma Steven K, Newman Lisa M, Sheldon Roger, Wang Li A: Enzymatic processes for the production of 4-substituted 3-hydroxybutyric acid derivatives and vicinal cyano, hydroxy substituted carboxylic acid esters. Codexis, May 31, 2006: EP1660669-A2

The present invention provides methods and composition for preparing 4-substituted 3-hydroxybutyric acid derivatives by halohydrin dehalogenase-catalyzed conversion of 4-halo-3-hydroxybutyric acid derivatives. The present invention further provides methods and compositions for preparing 4-halo-3-hyd ...


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S Christopher Davis, John H Grate, David R Gray, John M Gruber, Gjalt W Huisman, Steven K Ma, Lisa M Newman, Roger Sheldon, Li A Wang: Enzymatic processes for the production of 4-substituted 3-hydroxybutyric acid derivatives. Maxygen, July 15, 2004: US20040137585-A1

The present invention provides methods and compositions for preparing 4-substituted 3-hydroxybutyric acid derivatives by halohydrin dehalogenase-catalyzed conversion of 4-halo-3-hydroxybutyric acid derivatives. The present invention further provides methods and compositions for preparing 4-halo-3-hy ...