41
William F Crismore, Nigel A Surridge, Daniel R McMinn, Richard J Bodensteiner, Eric R Diebold, R Dale Delk, David W Burke, Jiaxiong Jason Ho, Robert Kitchel Earl, Brian A Heald: Electrochemical biosensor test strip. Roche Diagnostics Corporation, Brinks Hofer Gilson & Lione, August 7, 2001: US06270637 (314 worldwide citation)

An electrochemical biosensor test strip with four new features. The test strip includes an indentation for tactile feel as to the location of the strips sample application port. The sample application port leads to a capillary test chamber, which includes a test reagent. The wet reagent includes fro ...


42
Martin Gerber, Matthias Essenpreis, Wolfgang Petrich: Subcutaneous analyte sensor. Roche Diagnostics Operations, Sujatha Subramaniam, Roche Diagnostics Operations, October 4, 2005: US06952603 (310 worldwide citation)

Assembly and method for measuring the concentration of an analyte in a biological matrix. The assembly includes an implantable optical-sensing element that comprises a body, and a membrane mounted on the body in a manner such that the membrane and the body define a cavity. The membrane is permeable ...


43
Stanley T Crooke: Oligoribonucleotides and ribonucleases for cleaving RNA. Isis Pharmaceuticals, Woodcock Washburn Kurtz Mackiewicz & Norris, August 22, 2000: US06107094 (308 worldwide citation)

Oligomeric compounds including oligoribonucleotides and oligoribonucleosides are provided that have subsequences of 2'-pentoribofuranosyl nucleosides that activate dsRNase. The oligoribonucleotides and oligoribonucleosides can include substituent groups for increasing binding affinity to complementa ...


44
Curtis A Birnbach: Device for modulating and reflecting electromagnetic radiation employing electro-optic layer having a variable index of refraction. Quantum Diagnostics, Ostrolenk Faber Gerb & Soffen, November 22, 1988: US04786128 (301 worldwide citation)

A multi-layer device for modulating and reflecting light. The device is formed of an electro-optic layer with a variable index of refraction sandwiched between two other layers having a pre-determined index of refraction. An electric field applied across the electro-optic layer controls the index of ...


45
Joel R Mitchen: Blood collection and testing method. Safety Diagnostics, Quarles & Brady, May 14, 1991: US05014718 (299 worldwide citation)

A relatively painless method of safely collecting and testing blood comprises piercing a patient's skin, bathing the pierced area with a vehicle liquid and collecting a sample of the vehicle liquid and any blood on a test disk in the apparatus. A novel disposable apparatus for practicing the method ...


46
Joel S Douglas, Jeffrey N Roe, Henry M Grage: Methods and apparatus for expressing body fluid from an incision. Mercury Diagnostics, Burns Doane Swecker & Mathis L, September 14, 1999: US05951493 (295 worldwide citation)

A sample of a body fluid such as blood or interstitial fluid is obtained from a body by lancing a portion of a user's skin, preferably in an area other than a finger tip, to form an incision. After the needle has been removed from the incision, a force is applied to depress the skin in a manner form ...


47
David S Breed: System and method for vehicle diagnostics. Automotive Technologies International, Brian Roffe, September 5, 2006: US07103460 (290 worldwide citation)

Method and system for diagnosing whether vehicular components are operating abnormally based on data obtained from sensors arranged on a vehicle. In a training stage, output from the sensors during normal operation of the components is obtained, each component is adjusted to induce abnormal operatio ...


48
Piet H C Moerman, Jerome F McAleer, Matthias Stiene: Combined lancet and electrochemical analyte-testing apparatus. Diabetes Diagnostics, March 16, 2004: US06706159 (289 worldwide citation)

An apparatus for detection and quantitation of an electrochemically-detectable analyte, such as glucose, in blood or interstitial fluid includes a meter unit, a lancet and an electrochemical sensor. Of these components, the meter is preferably reusable, while the lancet and the electrochemical senso ...


49
Kurt R Linberg, Randy L Merry, Chester G Nelson, William J Plombon: Virtual remote monitor, alert, diagnostics and programming for implantable medical device systems. Medtronic, Girma Wolde Michael, December 24, 2002: US06497655 (289 worldwide citation)

A plurality of co-operative and complementary software programs are implemented in a web-enabled high speed computer system to remotely monitor, manage and modify the operational and functional parameters of a plurality of implanted medical devices (IMDs). The system utilizes virtual electrophysiolo ...


50
Dario Cabib, Robert A Buckwald, Zvi Malik, Yuval Garini, Nir Katzir, Dirk G Soeknsen: Spectral bio-imaging methods for biological research, medical diagnostics and therapy. Applied Spectral Imaging, Mark M Friedman, July 21, 1998: US05784162 (288 worldwide citation)

According to the present invention there are provided spectral imaging methods for biological research, medical diagnostics and therapy comprising the steps of (a) preparing a sample to be spectrally imaged; (b) viewing the sample through an optical device, the optical device being optically connect ...