1
Stéphane De Lombaert
Rajagopal Bakthavatchalam, Charles A Blum, Harry L Brielmann, James William Darrow, Stéphane De Lombaert, Alan Hutchison, Jennifer Tran, Xiaozhang Zheng, Richard Louis Elliott, Marlys Hammond: Spiro[isobenzofuran-1,4′-piperidin]-3-ones and 3H-spiroisobenzofuran-1,4′-piperidines. Pfizer, Neurogen Corporation, Ladas & Parry, May 20, 2003: US06566367 (57 worldwide citation)

Substituted spiro[isobenzofuran-1,4′-piperidin]-3-ones and 3H-spiroisobenzofuran-1,4′-piperidines capable of modulating NPY5 receptor activity are provided. Such compounds may be used to modulate ligand binding to NPY5 receptors in vivo or in vitro, and are particularly useful in the treat ...


2
Tarran Jones
Mary M Bendig, Olivier J Leger, Jose Saldanha, Tarran S Jones, Ted A Yednock: Methods of inhibiting alpha-4-dependent interactions with VCAM-1 with anti-VLA-4 antibodies. Elan Pharmaceuticals, Crowell & Moring, August 21, 2012: US08246958 (31 worldwide citation)

The invention provides methods of treatment using humanized immunoglobulins that specifically bind to alpha-4 integrin. The methods are useful for treatment of asthma, atherosclerosis, AIDS dementia, diabetes, inflammatory bowel disease, rheumatoid arthritis, transplant rejection, graft versus host ...


3
Stéphane De Lombaert
Stéphane De Lombaert, Alan Hutchison, Xiaozhang Zheng: Spiro[isobenzofuran-1,4′-piperidin]-3-ones and 3H-spiroisobenzofuran-1,4′-piperidines. Neurogen Corporation, Lawson & Weitzen, Sonia K Guterman, September 13, 2005: US06943199 (18 worldwide citation)

Substituted spiro[isobenzofuran-1,4′-piperidin]-3-ones and 3H-spiroisobenzofuran-1,4′-piperidines capable of modulating NPY5 receptor activity are provided. Such compounds may be used to modulate ligand binding to NPY5 receptors in vivo or in vitro, and are particularly useful in the treatment of a ...


4
Tarran Jones
Mary M Bendig, Olivier J Leger, Jose Saldanha, Tarran S Jones, Ted A Yednock: Humanized anti-VLA4 immunoglobulins. Elan Pharaceuticals, Crowell & Moring, October 14, 2008: US07435802 (6 worldwide citation)

The invention provides methods of treatment using humanized immunoglobulins that specifically bind to alpha-4 integrin. The methods are useful for treatment of asthma, atherosclerosis, AIDS dementia, diabetes, inflammatory bowel disease, rheumatoid arthritis, transplant rejection, graft versus host ...


5
Lyle M Allen III: Patient-operated glucose monitor and diabetes management system. Healthware Corporation, March 15, 1988: US04731726 (1201 worldwide citation)

A monitor system is provided which includes means for measuring blood glucose values and for generating glucose data signals, monitor means coupled to the measuring means and including means for inputting patient data, means for transmitting and receiving data to and from the monitor means, and comp ...


6
Stephen J Brown: Modular microprocessor-based health monitoring system. Raya Systems, Christensen O Connor Johnson & Kindness, April 26, 1994: US05307263 (973 worldwide citation)

A modular self-care health monitoring system which employs a small handheld microprocessor-based unit (12) such as a compact video game system of the type that includes a display screen (28), switches for controlling device operation (30,32,34,36,38) and a program cartridge (41,42,43) that is insert ...


7
David R L Worthington, Stephen J Brown: Diabetes management system and method for controlling blood glucose. Health Hero Network, Lumen Intellectual Property Services, October 13, 1998: US05822715 (963 worldwide citation)

A diabetes management system for predicting a future blood glucose value of a patient and for recommending a corrective action to the patient when the future blood glucose value lies outside of a target range. The system includes a patient-operated apparatus for measuring blood glucose values and fo ...


8
David R L Worthington, Stephen J Brown: Diabetes management system and method for controlling blood glucose. Health Hero Network, Black Lowe & Graham PLLC, April 30, 2002: US06379301 (843 worldwide citation)

A diabetes management system for predicting a future blood glucose value of a patient and for recommending a corrective action to the patient when the future blood glucose value lies outside of a target range. The system includes a patient-operated apparatus for measuring blood glucose values and fo ...


9
Andreas G F Beckers: Diabetes management system and apparatus. Diva Medical Systems, Richard P Crowley, May 28, 1991: US05019974 (752 worldwide citation)

A system and apparatus for efficient medical control of a medical condition such as diabetes comprises a recorder, an interface and a master computer. The master computer develops a program of therapy which is downloaded into the recorder which then reminds the patient of any therapy due and records ...


10
Douglas J Allen, Kirk W Johnson, Robert S Nevin: Hydrophilic polyurethane membranes for electrochemical glucose sensors. Eli Lilly and Company, Woodward Emhardt Naughton Moriarty & McNett, June 21, 1994: US05322063 (749 worldwide citation)

Homogeneous membranes permeable to oxygen and glucose composed of hydrophilic polyurethanes that are capable of absorbing from 10 to 50% of their dry weight of water. Variations in the composition of the hydrophilic polyurethanes make possible the fabrication of membranes in which the ratios of the ...



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