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Richard Clark, Fumiyoshi Matsuura, Eita Emori, Masanobu Shinoda, Shunji Kasai, Hideki Yoshitomi, Kazuto Yamazaki, Takashi Inoue, Sadakazu Miyashita, Taro Hihara: Cyclic compound and PPAR agonist. Eisai, Birch Stewart Kolasch & Birch, May 13, 2008: US07371777 (5 worldwide citation)

The present invention provides a novel compound having an excellent PPAR agonist action. More specifically, it provides a compound represented by the following formula, a salt thereof, an ester thereof or a hydrate of them. Wherein a, b and c are the same as or different from one another and each re ...


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Clark Richard, Matsuura Fumiyoshi, Emori Eita, Shinoda Masanobu, Kasai Shunji, Yoshitomi Hideki, Yamazaki Kazuto, Inoue Takashi, Miyashita Sadakazu, Hihara Taro: Cyclic compound and ppar agonist. Eisai, September 1, 2004: EP1452521-A1 (1 worldwide citation)

The present invention provides a novel compound having an excellent PPAR agonist action. More specifically, it provides a compound represented by the following formula, a salt thereof, an ester thereof or a hydrate of them. Wherein a, b and c are the same as or different from one another and each re ...


3
Richard Clark, Fumiyoshi Matsuura, Eita Emori, Masanobu Shinoda, Shunji Kasai, Hideki Yoshitomi, Kazuto Yamazaki, Takashi Inoue, Sadakazu Miyashita, Taro Hihara: Cyclic compound and ppar agonist. Birch Stewart Kolasch & Birch, January 20, 2005: US20050014833-A1

The present invention provides a novel compound having an excellent PPAR agonist action. More specifically, it provides a compound represented by the following formula, a salt thereof, an ester thereof or a hydrate of them. Wherein a, b and c are the same as or different from one another and each re ...


4
Clark Richard, Matsuura Fumiyoshi, Emori Eita, Shinoda Masanobu, Kasai Shunji, Yoshitomi Hideki, Yamazaki Kazuto, Inoue Takashi, Miyashita Sadakazu, Hihara Taro: Cyclic compound and ppar agonist. Eisai, Clark Richard, Matsuura Fumiyoshi, Emori Eita, Shinoda Masanobu, Kasai Shunji, Yoshitomi Hideki, Yamazaki Kazuto, Inoue Takashi, Miyashita Sadakazu, Hihara Taro, FURUYA Kaoru, February 27, 2003: WO/2003/016265

A compound represented by the following formula, which has excellent PPAR agonistic activity: (I) wherein a, b, and c each is 0 to 4; R1 to R6 each represents hydrogen, hydroxy, cyano, halogeno, etc.; A1 and A2 each represents a single bond, oxygen, etc.; L, M, and T each repres ...