1
Gordon Elger, Stewart T Leslie, Sandra T A Malkowska, Ronald B Miller, Philip J Neale: Controlled release pharmaceutical composition. Euroceltique, Steinberg & Raskin, May 30, 1989: US04834985 (219 worldwide citation)

A solid, controlled release, pharmaceutical composition comprising an active ingredient incorporated in a matrix comprising a first substance selected from a water soluble polydextrose and a water soluble cyclodextrin and a second substance selected from a C.sub.12 -C.sub.36 fatty alcohol and a poly ...


2
Gordon A Elger, Stewart T Leslie, Sandra T A Malkowska, Ronald B Miller, Philip J Neale: Controlled release pharmaceutical composition. Euroceltique, Steinberg & Raskin, May 9, 1989: US04828836 (198 worldwide citation)

A solid, controlled release, pharmaceutical composition comprising an active ingredient incorporated in a controlled release matrix comprising a water soluble polydextrose.


3
Thinnayam N Krishnamurthy: Controlled release matrix for pharmaceuticals. Euro Celtique, Clifford M Davidson, September 22, 1998: US05811126 (126 worldwide citation)

A controlled release pharmaceutical composition for oral administration in humans or animals, comprising a controlled release matrix comprising a pharmaceutically acceptable sodium alginate, a pharmaceutically acceptable water swellable polymer, a pharmaceutically acceptable C.sub.2 -C.sub.50 edible ...


4
Ian Keith Smith, Grant Wayne Heinicke: Analgesic immediate and controlled release pharmaceutical composition. F H Faulding & Co, Cohen Pontani Lieberman & Pavane, February 27, 2001: US06194000 (108 worldwide citation)

Disclosed is a method for the therapeutic treatment of pain related to wind up in a human or animal. The method of the invention is practiced by administering to the subject an effective amount of an analgesic pharmaceutical composition which includes a NMDA receptor antagonist in an immediate relea ...


5
Daniel J Doyon, Madurai G Ganesan, Wendy A Preston, Nitin V Sheth: Controlled release pharmaceutical compositions from spherical granules in tabletted oral dosage unit form. American Cyanamid Company, H G Jackson, James V Costigan, February 1, 1994: US05283065 (102 worldwide citation)

A controlled release pharmaceutical composition in oral dosage unit form comprising a tablet comprising a therapeutically effective number of active spherical granules comprising an effective amount of active medicament, a pharmaceutically acceptable normally solid diluent adapted to form a diffusab ...


6
Rosa Martani, Elisabeth Le Huede, Jeanne Dumas: Controlled release pharmaceutical composition. Euroceltique, Steinberg & Raskin, May 30, 1989: US04834965 (98 worldwide citation)

A solid, controlled release pharmaceutical composition is provided with enhanced levels of control over drug release. The composition comprises an acid addition salt or a quarternary ammonium salt of an organic base drug complexed with an anionic surfactant and distributed in a matrix of a hydrophil ...


7
Joanne Heafield, Stewart T Leslie, Sandra T A Malkowska, Philip J Neale: Spheroids. Euroceltique, Nixon & Vanderhye, September 19, 1989: US04867985 (95 worldwide citation)

A controlled release pharmaceutical composition contains a number of spheroids, the spheroids containing a water-insoluble drug dispersed in a controlled release matrix. The matrix contains between 70% and 99.5% (by weight) of microcrystalline cellulose, between 0.5% and 4% (by weight) of a cellulos ...


8
Andreas Supersaxo, Jim H Kou: Controlled delivery of pharmaceuticals from preformed porous polymeric microparticles. Syntex, William Schmonsees, Theodore J Leitereg, Alan M Krubiner, November 28, 1995: US05470582 (79 worldwide citation)

A controlled release pharmaceutical composition comprising a physiologically active agent dispersed in preformed porous polymeric microparticles is provided. The active agent concentration may be up to about 10% by weight to achieve controlled release. Each of the porous microparticles has a plurali ...


9
Stewart T Leslie, Sandra T A Malkowska, Joanne Marchant, Philip J Neale: Spheroids. Euroceltique, Steinberg & Raskin, July 4, 1989: US04844910 (67 worldwide citation)

A controlled release pharmaceutical composition comprising a plurality of film coated spheroids, the film coated spheroids comprising a 3-alkylxanthine, a non-water soluble spheronising agent and between 4% and 9% (by weight) water, wherein the in-vitro dissolution rate of the 3-alkylxanthine from t ...


10
Vaghefi Farid, Liversidge Gary G, Ruddy Stephen B, Cooper Eugene R: Abuse-resistant pharmaceutical compositions. Verion, Elan Corporation, Vaghefi Farid, Liversidge Gary G, Ruddy Stephen B, Cooper Eugene R, SAVITZKY Martin F, April 1, 2004: WO/2004/026262 (58 worldwide citation)

An abuse-resistant controlled release pharmaceutical composition comprising a pharmaceutically effective amount of discrete particles of an active capable of abuse, wherein surfaces of said particles are wetted with a water insoluble coating material, and preferably wherein said composition comprise ...



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