1

2
Francis G Hutchinson: Continuous release pharmaceutical compositions. Imperial Chemical, Cushman Darby & Cushman, August 30, 1988: US04767628 (247 worldwide citation)

Pharmaceutical compositions, comprising a polylactide and a pharmacologically active, acid stable polypeptide, which when placed in an aqueous physiological environment release the polypeptide at an approximately constant rate in an essentially monophasic manner, with a minimal, or no induction peri ...


3
Camble Roger, Timms David, Wilkinson Anthony James: Continuous release pharmaceutical compositions comprising a polypeptide covalently conjugated to a water soluble polymer.. Ici, March 4, 1992: EP0473268-A2 (67 worldwide citation)

Pharmaceutical compositions for continuous release of a physiologically active substance in which the physiologically active substance comprises a polypeptide covalently conjugated to a water soluble polymer show particularly desirable release characteristics. Polypeptides for use in the pharmaceuti ...


4
Francis G Hutchinson: Continuous release pharmaceutical compositions. Zeneca, Cushman Darby & Cushman, November 22, 1994: US05366734 (56 worldwide citation)

Pharmaceutical compositions, comprising a polylactide and a pharmacologically active, acid stable polypeptide, which when placed in an aqueous physiological environment release the polypeptide at an approximately constant rate in an essentially monophasic manner, with a minimal, or no induction peri ...


5
Francis G Hutchinson: Continuous release pharmaceutical compositions formed by freeze drying acetic acid solutions of polylactide. Imperial Chemical, Cushman Darby & Cushman, April 2, 1991: US05004602 (55 worldwide citation)

Pharmaceutical compositions, comprising a polylactide and a pharmacologically active, acid stable polypeptide, which when placed in an aqueous physiological equipment release the polypeptide at an approximately constant rate in an essentially monophasic manner, with a minimal, or no induction period ...


6
Roger Camble, David Timms, Anthony J Wilkinson: Continuous release pharmaceutical compositions. Imperial Chemical, Cushman Darby & Cushman, June 14, 1994: US05320840 (44 worldwide citation)

Pharmaceutical compositions for continuous release of a physiologically active substance in which the physiologically active substance comprises a polypeptide covalently conjugated to a water soluble polymer show particularly desirable release characteristics. Polypeptides for use in the pharmaceuti ...


7
Hutchinson Francis G: Compose pharmaceutique a liberation continue, Continuous release pharmaceutical compositions. Zeneca, SMART & BIGGAR, June 12, 1984: CA1169090 (8 worldwide citation)

ABSTRACT Pharmaceutical compositions, comprisinga polylactide and a pharmacologically active, acidstable polypeptide, which when placed in an aqueousphysiological environment release the polypeptide atan approximately constant rate in an essentiallymonophasic manner, with a minimal, or no inductionp ...


8
Camble Roger, Timms David, Wilkinson Anthony James: Continuous release pharmaceutical compositions. Ici, January 29, 1992: GB2246295-A (5 worldwide citation)

Pharmaceutical compositions for continuous release of a physiologically active substance in which the physiologically active substance comprises a polypeptide covalently conjugated to a water soluble polymer show particularly desirable release characteristics. Polypeptides for use in the pharmaceuti ...


9

10